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Isaac Ciechanover, Partner at Polaris Partners

Isaac Ciechanover

Partner @ Polaris Partners

San Francisco, United States

Isaac Ciechanover is a physician, investor and entrepreneur driven by a passion to improve the practice of medicine. Motivated by the belief that the majority of medical discoveries still lie ahead, he has dedicated the past 20 years to working with entrepreneurs and life sciences organizations to advance medicine through innovation and technology.He founded Atara Biotherapeutics in October 2012. Previously, he was a partner in the life sciences practice at Kleiner Perkins Caufield & Byers. Earlier as Celgene’s Executive Director in Business Development, he spearheaded the company’s venture capital efforts and led licensing and M&A activities with an aggregate value of more than $6.7 billion. Also at Celgene, he was Global Project Leader for the company’s first clinical-stage biologic therapy. Isaac has also held business development and venture capital roles at Amylin Pharmaceuticals, Pequot Ventures’ healthcare practice and Pfizer. Intellectually curious (and undeterred by student debt), Isaac holds a B.A. in Psychology from Stanford University, an M.Phil. in Epidemiology from Cambridge University, an M.D. from Weill Cornell Medical College and an MBA from Harvard Business School. For fun, he enjoys cycling, scuba diving and building Lego with his two children. His all-time favorite albums are Pink Floyd’s “The Dark Side of the Moon,” Radiohead’s “OK Computer” and Ruggero Leoncavallo’s Italian opera, Pagliacci, with Herbet Von Karajan conducting.

Total investments:
2
Last investment:
Lead investor:
50%

Last updated:

Industries Isaac Ciechanover invests in

BiotechnologyMedicalGeneticsBiopharmaHealth Care

Stages Isaac Ciechanover invests in

SeedSeries C

Countries Isaac Ciechanover invests in

United States

Investment Focus

Industry

  • Biotechnology 2 (100%)
  • Medical 1 (50%)
  • Genetics 1 (50%)
  • Biopharma 1 (50%)
  • Health Care 1 (50%)
See all 7 industries →

Stage

  • Seed 1 (50%)
  • Series C 1 (50%)

Investments

CompanyDescriptionRoundLinks
EGenesis EGenesis
EGenesis operates as a biotechnology company. The Company focuses on leveraging genome editing technology to deliver safe and effective human transplantable cells, tissues, and organs. eGenesis serves patients worldwide. $125M / Series C / Mar 02, 2021
Auron Therapeutics Auron Therapeutics
Auron Therapeutics is to develop therapies to cure cancer by radically changing the paradigm of cancer therapeutics from cell killing, to transformation of malignant cells into normal cells. This transformation, called differentiation therapy, reactivates endogenous cellular programs to elicit tumor cell maturation and the transition from cancerto normal tissue. Its unique platforms allow for integration of large-omic datasets and miniaturized high throughput flow cytometry to rapidly identify and validate multiple targets and drugs in primary human patient samples. $12.8M / Seed / Jan 28, 2021

Co-Investors

Polaris Partners

About Polaris Partners

VC Fund · Boston, United States

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

Polaris Partners Contacts

NameEmailPhoneSocials
Sharif Vakili
Sharif Vakili Associate
Alan Crane
Alan Crane Partner and Entrepreneur
Amir Nashat
Amir Nashat Managing Partner

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FAQ

What does Isaac Ciechanover invest in?

Isaac Ciechanover invests primarily in Biotechnology, Medical and Genetics startups, most often at Seed and Series C stage. Most of the 2 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

When did Isaac Ciechanover last invest?

The most recent investment recorded for Isaac Ciechanover closed in Mar 2021. Shizune tracks 2 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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