Flagship Pioneering
VC Fund
Cambridge, United States
Flagship Pioneering is a VC fund in Cambridge focused on Biotechnology and Health Care. Flagship Pioneering conceives, creates, resources, and grows first-in-category ventures to transform human health and sustainability. The company accelerates Flagship Pioneering’s advances in biology, engineering, medicine, energy, and beyond. The firm harnesses science and entrepreneurialism to envision alternative futures, beginning with seemingly unreasonable propositions and navigating to transformational outcomes through an evolutionary methodology. Flagship Pioneering combines innovative capacity, entrepreneurial leadership, and professional capital management in a single enterprise that systematically produces first-in-category companies.
- Total investments:
- 257
- Last investment:
- Lead investor:
- 47%
- Fund size:
- $2.6B
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Flagship Pioneering invests in
Stages Flagship Pioneering invests in
Countries Flagship Pioneering invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 24 contacts → | |||
Round size
- Series A
- $6.6M–$75M
- Series B
- $11M–$230M
- Series C
- $12M–$123M
Investment Focus
Industry
- Biotechnology 67 (26%)
- Health Care 36 (14%)
- Medical 28 (11%)
- Therapeutics 24 (9%)
- Pharmaceutical 14 (5%)
Stage
- Series B 50 (19%)
- Series C 40 (16%)
- Series A 39 (15%)
- Venture - Series Unknown 15 (6%)
- Series D 14 (5%)
Country
- United States 97 (38%)
- Canada 1 (0%)
- United Kingdom 1 (0%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Geoffrey von Maltzahn
General Partner
|
General Partner | Total investments: 1 | Find email | |
Hari Pujar
Operating Partner
|
Operating Partner | Total investments: 1 | Find email | |
Paul Biondi
Executive Partner & President
|
Executive Partner & President | Total investments: 1 | Find email | |
Thomas de Vlaam
Co-Founder FL86
|
Co-Founder FL86 | Total investments: 3 | Find email | |
Avak Kahvejian
General Partner
|
General Partner | Total investments: 7 | Find email | |
| See all 24 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Iris Labs is an AI company focused on improving human wellbeing through personalized AI experiences for self-awareness, and personal growth. | $20M / Venture - Series Unknown / Oct 06, 2026 | ||
| Serif Biomedicines is pioneering Modified DNA as a new type of biotechnology. Serif combines nucleic acid chemistry, synthetic biology, delivery technology, and artificial intelligence to develop programmable, scalable, long-lasting, and redosable DNA therapies. | $50M / Venture - Series Unknown / Apr 21, 2026 | ||
| Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express, and when, where, and in what order.By manipulating this system with our unique Gene Traffic ControlTM platform, Foghorn will change how genes turn “on” and “off.” Unlike approaches that edit genes, this novel way of thinking will alter whatour DNA has in store for us—and rewrite destiny for millions of people living with disease.With Gene Traffic ControlTM Foghorn is pioneering a new, major class of drug targets to develop unprecedented therapies for cancer and other serious diseases. We have already validated multiple targets, are in the process of developing drug candidates in multiple types of cancer and are beginning to explore other diseases. | $50M / Post-IPO Equity / Jan 09, 2026 | ||
| Expedition Medicine's industry-leading chemoproteomics data generating engine learns the rules of molecular reactivity, enabling programmable small molecule medication design. | $50M / Series A / Oct 22, 2025 | ||
| Lila Sciences is a platform that uses artificial intelligence to support research in life sciences, chemical sciences, and materials sciences. It develops AI-driven tools and autonomous labs to improve research efficiency and facilitate scientific discoveries. The platform is designed to enhance various aspects of the scientific method andcontribute to advancements in technology and innovation. | $115M / Series A / Oct 14, 2025 | ||
| Extuitive AI agents develop multiple product and ad versions and select the most effective concepts based on market trends. | $20M / Seed / Sep 18, 2025 | ||
| Lila Sciences is a platform that uses artificial intelligence to support research in life sciences, chemical sciences, and materials sciences. It develops AI-driven tools and autonomous labs to improve research efficiency and facilitate scientific discoveries. The platform is designed to enhance various aspects of the scientific method andcontribute to advancements in technology and innovation. | $235M / Series A / Sep 14, 2025 | ||
| Terrana's innovative technological platform enables resilient agriculture in a fast changing world by providing RNA-based plant health solutions. | Jul 01, 2025 | ||
| Terrana's innovative technological platform enables resilient agriculture in a fast changing world by providing RNA-based plant health solutions. | $50M / Series B / Jul 01, 2025 | ||
| Etiome is disrupting the progression of disease before it becomes debilitating and irreversible by developing and deploying Biostaged Medicines. | $50M / Series A / Apr 24, 2025 | ||
| See all 257 investments → | |||
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FAQ
What does Flagship Pioneering invest in?
Flagship Pioneering invests primarily in Biotechnology, Health Care and Medical startups, most often at Series B and Series C stage. Most of the 257 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What round sizes does Flagship Pioneering invest in?
Flagship Pioneering typically joins rounds of $6.6M–$75M at Series A, $11M–$230M at Series B and $12M–$123M at Series C. These are whole funding-round sizes, not Flagship Pioneering's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Flagship Pioneering took part in.
How do I contact Flagship Pioneering?
Public channels for Flagship Pioneering include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Flagship Pioneering?
The team at Flagship Pioneering includes Geoffrey von Maltzahn (General Partner), Hari Pujar (Operating Partner) and Paul Biondi (Executive Partner & President), among 24 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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