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Avichay Nissenbaum, Investor at Medisafe

Avichay Nissenbaum

Investor @ Medisafe

Avichay Nissenbaum is a seed investor at Medisafe focused on Software and SaaS. Avichay Nissenbaum has over 25 years of experience in the software industry and is Co-founder and General Partner at lool ventures, an early stage venture fund focused on Internet/Mobile/Media in Israel.Prior to lool ventures Avichay served as the Chief Executive Officer and co-founder of Yedda.com, (Acquired by AOL), and a vicepresident at AOL and AOL Israel Country manager. Prior to Yedda.com, Mr. Nissenbaum co-founded SmarTeam, a market leader in the PLM (Product Lifecycle Management) domain. SmarTeam was subsequently acquired by Dassault Systems (NASDAQ: DASTY). Avichay serves on several boards including Perion (NASDAQ:PERI), Tipa Corp., Mabaya, Zooz, Medisafe, MyPermissions, EasySocialShop, Mabaya, Sensibo and several additional startup companies and advises various startups and entrepreneurs.

Total investments:
25
Last investment:
Lead investor:
40%

Last updated:

Industries Avichay Nissenbaum invests in

SoftwareSaaSAgTechE-CommerceAgriculture

Stages Avichay Nissenbaum invests in

SeedSeries ASeries BSeries CSeries D

Countries Avichay Nissenbaum invests in

IsraelUnited States

Investment Focus

Industry

  • Software 3 (12%)
  • SaaS 2 (8%)
  • AgTech 2 (8%)
  • E-Commerce 2 (8%)
  • Agriculture 2 (8%)
See all 39 industries →

Stage

  • Seed 9 (36%)
  • Series A 3 (12%)
  • Series B 3 (12%)
  • Series C 3 (12%)
  • Series D 1 (4%)
See all 6 stages →

Country

  • Israel 8 (32%)
  • United States 3 (12%)

Investments

CompanyDescriptionRoundLinks
Beewise Beewise
Beewise offers robotic beehives that operate with minimal human intervention, by utilizing AI-powered precision robotics. The company's solution automates all beekeeping activities in order to increase yield, reduce colony loss, and eliminate the use of chemical pesticides. We are the first comprehensive solution that keeps bees alive, inspite of all the stressors and challenges they face, allowing them to thrive, pollinate, and produce honey. $50M / Series D / Jun 09, 2025
Beewise Beewise
Beewise offers robotic beehives that operate with minimal human intervention, by utilizing AI-powered precision robotics. The company's solution automates all beekeeping activities in order to increase yield, reduce colony loss, and eliminate the use of chemical pesticides. We are the first comprehensive solution that keeps bees alive, inspite of all the stressors and challenges they face, allowing them to thrive, pollinate, and produce honey. $80M / Series C / Mar 30, 2022
Inner Cosmos Inner Cosmos
The Evolution of Medicine $10M / Seed / Mar 30, 2022
Lightico Lightico
Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. $15M / Series B / Jul 19, 2021
Medisafe Medisafe
Medisafe is a digital patient engagement platform, empowering patients to stay on top of all their medications. Its approach leverages the billions of data points collected to personalize patient engagement and improve adherence and persistence to medications.By addressing the major challenges of medication management utilizing a datascience-driven approach, Medisafe improves patient adherence and quality of care. The company provides its pharma and payer partners the opportunity to engage each patient on an individual level, supporting them throughout the entire patient journey, and provides unique insights on behavior patterns critical for improving the patient experience. Medisafe had shown over numerous studies, both retrospective with tens of thousands of patients as well as RCTs, that its solutions improve adherence by up to 20%.Founded following an accidental insulin overdose of the founder's father, the Medisafe solution currently has nearly 5 million registered users across iOS and Android smartphones, tablets, wearables, and Web solutions, who have recorded over 2 billion medication doses. Nearly 200,000 users have rated the app an average of 4.7 out of 5 stars in the App Store and Google Play store, making it the Top Rated solution in the category. Their accolades include Gartner Cool Vendors, Traction winner (Health 2.0 startup competition), Fast Company Most Innovative in Healthcare, Google and Apple Editors' Choice and Top Developer, etc. $30M / Series C / Feb 25, 2021
Lightico Lightico
Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. $11.2M / Series B / Nov 10, 2020
Lawgeex Lawgeex
LawGeex is transforming legal. For companies who want to spend less time on contracts and focus on high-impact work, LawGeex automates the review and approval of everyday contracts with unparalleled accuracy, consistency, and scalability through our advanced AI platform.LawGeex is recognized by Gartner, Wired magazine, and CB Insights as aleading force in bringing innovation and technology to the legal world – and is trusted by global firms such as eBay, Bain & Company, and White & Case. $20M / Series C / May 12, 2020
Lightico Lightico
Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. $14.5M / Jul 09, 2019
Lawgeex Lawgeex
LawGeex is transforming legal. For companies who want to spend less time on contracts and focus on high-impact work, LawGeex automates the review and approval of everyday contracts with unparalleled accuracy, consistency, and scalability through our advanced AI platform.LawGeex is recognized by Gartner, Wired magazine, and CB Insights as aleading force in bringing innovation and technology to the legal world – and is trusted by global firms such as eBay, Bain & Company, and White & Case. $12M / Series B / Apr 17, 2018
Lightico Lightico
Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. Jan 31, 2018
See all 25 investments →

Co-Investors

Medisafe

About Medisafe

VC Fund · Boston, United States

Medisafe is a digital patient engagement platform, empowering patients to stay on top of all their medications. Its approach leverages the billions of data points collected to personalize patient engagement and improve adherence and persistence to medications.By addressing the major challenges of medication management utilizing a datascience-driven approach, Medisafe improves patient adherence and quality of care. The company provides its pharma and payer partners the opportunity to engage each patient on an individual level, supporting them throughout the entire patient journey, and provides unique insights on behavior patterns critical for improving the patient experience. Medisafe had shown over numerous studies, both retrospective with tens of thousands of patients as well as RCTs, that its solutions improve adherence by up to 20%.Founded following an accidental insulin overdose of the founder's father, the Medisafe solution currently has nearly 5 million registered users across iOS and Android smartphones, tablets, wearables, and Web solutions, who have recorded over 2 billion medication doses. Nearly 200,000 users have rated the app an average of 4.7 out of 5 stars in the App Store and Google Play store, making it the Top Rated solution in the category. Their accolades include Gartner Cool Vendors, Traction winner (Health 2.0 startup competition), Fast Company Most Innovative in Healthcare, Google and Apple Editors' Choice and Top Developer, etc.

Medisafe Contacts

NameEmailPhoneSocials
Jon Michaeli
Jon Michaeli EVP Marketing & Business Development
Julie Fishman
Julie Fishman Strategic Partnerships, Specialty Pharmacy and Hub Services
Karen Baker
Karen Baker CFO
Karen Gardner
Karen Gardner Vice President of Customer Success

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FAQ

What does Avichay Nissenbaum invest in?

Avichay Nissenbaum invests primarily in Software, SaaS and AgTech startups, most often at Seed and Series A stage. Most of the 25 investments tracked by Shizune back companies in Israel. The Investment Focus section breaks down every industry, stage and country in the portfolio.

When did Avichay Nissenbaum last invest?

The most recent investment recorded for Avichay Nissenbaum closed in Jun 2025. Shizune tracks 25 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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