# Avichay Nissenbaum

> Avichay Nissenbaum is a seed investor at Medisafe backing Software, SaaS and AgTech. See 25 investments, check sizes, portfolio. Updated Aug 2026.

- Type: Angel Investor
- Fund: [Medisafe](https://shizune.co/investors/profile/medisafe-project)
- Total investments: 25
- Last investment: Jun 2025
- Lead investor: 40%
- Last updated: Aug 2026
- LinkedIn: http://il.linkedin.com/in/avichayn
- X (Twitter): https://twitter.com/avichayn
- Website: http://lool.vc

Avichay Nissenbaum is a seed investor at Medisafe focused on Software and SaaS. Avichay Nissenbaum has over 25 years of experience in the software industry and is Co-founder and General Partner at lool ventures, an early stage venture fund focused on Internet/Mobile/Media in Israel.Prior to lool ventures Avichay served as the Chief Executive Officer and co-founder of Yedda.com, (Acquired by AOL), and a vicepresident at AOL and AOL Israel Country manager. Prior to Yedda.com, Mr. Nissenbaum co-founded SmarTeam, a market leader in the PLM (Product Lifecycle Management) domain. SmarTeam was subsequently acquired by Dassault Systems (NASDAQ: DASTY). Avichay serves on several boards including Perion (NASDAQ:PERI), Tipa Corp., Mabaya, Zooz, Medisafe, MyPermissions, EasySocialShop, Mabaya, Sensibo and several additional startup companies and advises various startups and entrepreneurs.

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Software | 3 | 12% |
| SaaS | 2 | 8% |
| AgTech | 2 | 8% |
| E-Commerce | 2 | 8% |
| Agriculture | 2 | 8% |

39 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 9 | 36% |
| Series A | 3 | 12% |
| Series B | 3 | 12% |
| Series C | 3 | 12% |
| Series D | 1 | 4% |

6 stages tracked in total.

### Country

| Country | Investments | Share |
| --- | --- | --- |
| Israel | 8 | 32% |
| United States | 3 | 12% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Beewise | Beewise offers robotic beehives that operate with minimal human intervention, by utilizing AI-powered precision robotics. The company's solution automates all beekeeping activities in order to increase yield, reduce colony loss, and eliminate the use of chemical pesticides. We are the first comprehensive solution that keeps bees alive, inspite of all the stressors and challenges they face, allowing them to thrive, pollinate, and produce honey. | $50M | Series D | Jun 09, 2025 |  |
| Beewise | Beewise offers robotic beehives that operate with minimal human intervention, by utilizing AI-powered precision robotics. The company's solution automates all beekeeping activities in order to increase yield, reduce colony loss, and eliminate the use of chemical pesticides. We are the first comprehensive solution that keeps bees alive, inspite of all the stressors and challenges they face, allowing them to thrive, pollinate, and produce honey. | $80M | Series C | Mar 30, 2022 |  |
| Inner Cosmos | The Evolution of Medicine | $10M | Seed | Mar 30, 2022 |  |
| Lightico | Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. | $15M | Series B | Jul 19, 2021 |  |
| Medisafe | Medisafe is a digital patient engagement platform, empowering patients to stay on top of all their medications. Its approach leverages the billions of data points collected to personalize patient engagement and improve adherence and persistence to medications.By addressing the major challenges of medication management utilizing a datascience-driven approach, Medisafe improves patient adherence and quality of care. The company provides its pharma and payer partners the opportunity to engage each patient on an individual level, supporting them throughout the entire patient journey, and provides unique insights on behavior patterns critical for improving the patient experience. Medisafe had shown over numerous studies, both retrospective with tens of thousands of patients as well as RCTs, that its solutions improve adherence by up to 20%.Founded following an accidental insulin overdose of the founder's father, the Medisafe solution currently has nearly 5 million registered users across iOS and Android smartphones, tablets, wearables, and Web solutions, who have recorded over 2 billion medication doses. Nearly 200,000 users have rated the app an average of 4.7 out of 5 stars in the App Store and Google Play store, making it the Top Rated solution in the category. Their accolades include Gartner Cool Vendors, Traction winner (Health 2.0 startup competition), Fast Company Most Innovative in Healthcare, Google and Apple Editors' Choice and Top Developer, etc. | $30M | Series C | Feb 25, 2021 |  |
| Lightico | Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. | $11.2M | Series B | Nov 10, 2020 |  |
| Lawgeex | LawGeex is transforming legal. For companies who want to spend less time on contracts and focus on high-impact work, LawGeex automates the review and approval of everyday contracts with unparalleled accuracy, consistency, and scalability through our advanced AI platform.LawGeex is recognized by Gartner, Wired magazine, and CB Insights as aleading force in bringing innovation and technology to the legal world – and is trusted by global firms such as eBay, Bain & Company, and White & Case. | $20M | Series C | May 12, 2020 |  |
| Lightico | Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. | $14.5M |  | Jul 09, 2019 |  |
| Lawgeex | LawGeex is transforming legal. For companies who want to spend less time on contracts and focus on high-impact work, LawGeex automates the review and approval of everyday contracts with unparalleled accuracy, consistency, and scalability through our advanced AI platform.LawGeex is recognized by Gartner, Wired magazine, and CB Insights as aleading force in bringing innovation and technology to the legal world – and is trusted by global firms such as eBay, Bain & Company, and White & Case. | $12M | Series B | Apr 17, 2018 |  |
| Lightico | Lightico streamlines sales & service processes and improves customer experience in the critical last mile of customer journeys. While on a call with a contact center agent, customers can digitally sign documents, complete forms, share documents/ID, see images and videos and process payments securely all from their mobile device. |  |  | Jan 31, 2018 |  |

10 of 25 investments shown.

## Co-investors
- [Mangrove Capital Partners](https://shizune.co/investors/profile/mangrove-capital-partners) — VC Fund, 4 deals together
- [Triventures](https://shizune.co/investors/profile/triventures) — VC Fund, 4 deals together
- [7wire Ventures](https://shizune.co/investors/profile/7wire-ventures) — VC Fund, 3 deals together
- [Capital One Ventures](https://shizune.co/investors/profile/capital-one-ventures) — VC Fund, 3 deals together
- [Crescendo Venture Partners](https://shizune.co/investors/profile/crecendo-venture-partners) — VC Fund, 3 deals together
- [LionBird](https://shizune.co/investors/profile/lionbird) — VC Fund, 3 deals together

## About Medisafe

VC Fund · Boston, United States

Medisafe is a digital patient engagement platform, empowering patients to stay on top of all their medications. Its approach leverages the billions of data points collected to personalize patient engagement and improve adherence and persistence to medications.By addressing the major challenges of medication management utilizing a datascience-driven approach, Medisafe improves patient adherence and quality of care. The company provides its pharma and payer partners the opportunity to engage each patient on an individual level, supporting them throughout the entire patient journey, and provides unique insights on behavior patterns critical for improving the patient experience. Medisafe had shown over numerous studies, both retrospective with tens of thousands of patients as well as RCTs, that its solutions improve adherence by up to 20%.Founded following an accidental insulin overdose of the founder's father, the Medisafe solution currently has nearly 5 million registered users across iOS and Android smartphones, tablets, wearables, and Web solutions, who have recorded over 2 billion medication doses. Nearly 200,000 users have rated the app an average of 4.7 out of 5 stars in the App Store and Google Play store, making it the Top Rated solution in the category. Their accolades include Gartner Cool Vendors, Traction winner (Health 2.0 startup competition), Fast Company Most Innovative in Healthcare, Google and Apple Editors' Choice and Top Developer, etc.

5 contacts available at Medisafe.

| Name | Title | Profile |
| --- | --- | --- |
| Avichay Nissenbaum | Investor | https://shizune.co/investors/profile/avichay-nissenbaum |
| Jon Michaeli | EVP Marketing & Business Development | https://shizune.co/investors/profile/jon-michaeli |
| Julie Fishman | Strategic Partnerships, Specialty Pharmacy and Hub Services | https://shizune.co/investors/profile/julie-fishman-618a |
| Karen Baker | CFO | https://shizune.co/investors/profile/karen-baker-3 |
| Karen Gardner | Vice President of Customer Success | https://shizune.co/investors/profile/karen-gardner |

## Similar investors

### Similar stage
- [Antler](https://shizune.co/investors/profile/antler-be9c) — VC Fund
- [Alumni Ventures](https://shizune.co/investors/profile/alumni-ventures-group) — VC Fund
- [Right Side Capital Management](https://shizune.co/investors/profile/right-side-capital-management) — VC Fund

## FAQ

### What does Avichay Nissenbaum invest in?

Avichay Nissenbaum invests primarily in Software, SaaS and AgTech startups, most often at Seed and Series A stage. Most of the 25 investments tracked by Shizune back companies in Israel. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### When did Avichay Nissenbaum last invest?

The most recent investment recorded for Avichay Nissenbaum closed in Jun 2025. Shizune tracks 25 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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