Trish Costello
Founder & CEO @ Portfolia
San Francisco, United States
Trish Costello is a seed investor at Portfolia in San Francisco focused on Health Care and Internet. The Portfolia team is led by Trish Costello, CEO Emeritus and co-founder of the prestigious Kauffman Fellows Program at the Center for Venture Education, whose Fellows operate at over 300 venture firms in 42 countries and collectively deploy $188B in venture capital.Costello served as the first President of CVE Capital Corp, a holding companyaffiliated with a $700 million Fund of Funds. Costello was on the startup team of the Kauffman Foundation, where she directed its efforts to enhance and expand equity investment in start-up companies and to build entrepreneurial ecosystems to support the development of fast-growth ventures. She created the Foundation’s Women’s Initiatives to develop high potential women entrepreneurs and to obtain greater equity investments in women’s businesses.Costello has held advisory or board positions with Springboard Enterprises, National Venture Capital Association, the Helzberg Entrepreneurial Mentoring Program, the National Science Foundation, the Global Entrepreneurship Monitor and various start-ups, universities, incubators and non-profit organizations. She currently serves on the Board of Directors of OsteoGenix and OsteoFi
- Total investments:
- 83
- Last investment:
- Lead investor:
- 4%
Last updated:
For AI agents: llms.txt
Industries Trish Costello invests in
Stages Trish Costello invests in
Countries Trish Costello invests in
Investment Focus
Industry
- Health Care 18 (22%)
- Internet 7 (8%)
- Software 7 (8%)
- Medical Device 7 (8%)
- Medical 6 (7%)
Stage
- Seed 24 (29%)
- Series A 15 (18%)
- Series B 5 (6%)
- Pre-Seed 2 (2%)
- Series C 2 (2%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Osteoboost
|
Bone Health Technologies specializes in developing medical devices designed for low bone mass. Its solution is a gentle mechanical stimulation that mimics weight-bearing exercise, providing an effective non-drug intervention. It offers the OsteoBoost device that relies on safe, natural, and effective whole-body vibration technology usingvibrational energy to turn stem cells into the bone using the same mechanisms as physical exercise. The company was founded in 2018 and is headquartered in San Francisco, California. | $8M / Series A / Apr 09, 2026 | |
GrubMarket
|
GrubMarket develops a website where sellers can offer foods and other items at wholesale prices to customers. It offers products such as organic foods, vegetables, gluten-free foods, snacks, drinks, pantries, home goods, health and beauty products, baby and kids' products, pets, non-GMO foods, paleo foods, cholesterol-free, and no trans-fatfoods.GrubMarket also offers foods from local farms, fisheries, commercial kitchens, certified home kitchens, and restaurants. Mike Xu founded GrubMarket in 2014, with its headquarters in Newark in California with an additional office in San Francisco in California. | $50M / Series H / Feb 02, 2026 | |
Innovare
|
Innovare is the edtech and data strategy app helping education leaders visualize, analyze, and use data to positively impact the communities they serve. | $2M / Seed / Apr 06, 2023 | |
Kanarys
|
Kanarys, Inc. is a technology company focused solely on providing the tools organizations need to create long-term, systemic change around Diversity, Equity, and Inclusion (DEI) challenges. Our platform provides the framework, benchmarking and data companies need to incorporate best-in-class DEI into every area of the organization, so they cantrack and measure impact on business outcomes. We are transforming DEI work with data | $5M / Series A / Feb 15, 2023 | |
Aria CV
|
Aria CV was founded in 2010 by Drs. John Scandurra and Karl Vollmers, formerly Fellows at the University of Minnesota’s Medical Devices Center. Aria has an exclusive license to certain patents from the University of Minnesota. Aria CV’s device has the potential to improve outcomes by reducing the workload on the right side of the heart. | Series B / Jul 14, 2022 | |
AEENA Dx
|
AEENA Dx is developing a saliva-based platform for the detection of cancer and disease. | Series A / Jun 01, 2022 | |
xCures
|
The convergence of genomics, precision medicine, and AI have created an unprecedented moment in the world of oncology. But the drug-centric way in which treatments are developed and the haphazard way in which knowledge about those treatments is captured and delivered to the point of care does not serve patients well. xCures is changing that, withan AI-based precision oncology platform that tightly integrates cancer research and care.The xCures platform runs a perpetual trial that captures Real World Evidence (RWE) to continuously learn from all patients, on all treatments, all the time. It coordinates treatment recommendations across all patients and institutions to match patients with the treatments that work. And it packages RWE for use by stakeholders across oncology, slashing the time and cost of drug development and saving lives. | Series A / Apr 11, 2022 | |
ShearShare
|
ShearShare is a verticalized SaaS that aggregates labor in a specialized market and provides affordable B2B tools to the self-employed stylist, starting with space to work and usage-based liability insurance. The company currently has the largest database of on-demand salon and barbershop space rentals and the most affordable leases in the market. | $2.3M / Seed / Mar 25, 2022 | |
Apollo Neuroscience
|
Apollo is a wellness product, the first clinically validated wearable that actively helps the body recover from stress. Apollo Neuroscience is a wellness product not intended to treat psychiatric disorders such as generalized anxiety disorder, social anxiety disorder, and panic disorder. Apollo is not a substitute for professional medical care. | $15M / Series A / Mar 17, 2022 | |
Nest Collaborative
|
Nest Collaborative is a provider of on-demand lactation counseling services intended to offer a collection of international board certified lactation consultants who conduct online, video appointments to help guide moms through the breastfeeding process. The company's services are offered via an online platform that offers reimbursed maternal,neonatal and lactation counseling services, enabling women to avail safe, convenient and affordable access to quality pediatric care, at home. | $4.3M / Seed / Mar 15, 2022 | |
| See all 83 investments → | |||
Co-Investors
About Portfolia
Portfolia connects sophisticated investors and leaders with entrepreneurial companies. Their platform enables users to collaborate with other members and lead investors to evaluate innovative products and teams, join diligence teams, and immerse themselves in the investment process. It is an investment fund designed for women while backinginnovative companies for returns and impact.
Portfolia Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Amber Caska
Investment Committee Member
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Trish Costello
Founder & CEO
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Valentina Vitols
Limited Partner
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Abbe Kligerman
Limited Partner
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Bethann Kassman
Deal Lead
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FAQ
What does Trish Costello invest in?
Trish Costello invests primarily in Health Care, Internet and Software startups, most often at Seed and Series A stage. Most of the 83 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
When did Trish Costello last invest?
The most recent investment recorded for Trish Costello closed in Apr 2026. Shizune tracks 83 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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