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Sofinnova Investments, VC Fund

Sofinnova Investments

VC Fund

Menlo Park, United States

Sofinnova Investments is a VC fund in Menlo Park focused on Biotechnology and Health Care. Sofinnova Ventures has partnered with entrepreneurs to secure initial funding, build successful teams, win key customers, and navigate acquisitions and IPOs. Sofinnova Ventures invests in Life Science and Technology start-ups. Their professionals are seasoned business operators, possessing deep domain and investment expertise. They know how to help entrepreneurs build successful, global businesses.

Total investments:
227
Last investment:
Lead investor:
30%
Fund size:
$500M
Last fund:

Last updated:

Industries Sofinnova Investments invests in

BiotechnologyHealth CareTherapeuticsPharmaceuticalMedical

Stages Sofinnova Investments invests in

Series BSeries ASeries CSeries DFunding Round

Countries Sofinnova Investments invests in

United StatesFranceSwitzerlandUnited KingdomThe Netherlands

Round sizes

Series A $7.3M–$100MSeries B $15M–$150MSeries C $15M–$94M

Contacts

NameEmailPhoneSocials
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Round size

Series A
$7.3M–$100M
Series B
$15M–$150M
Series C
$15M–$94M

Investment Focus

Industry

  • Biotechnology 108 (48%)
  • Health Care 69 (30%)
  • Therapeutics 50 (22%)
  • Pharmaceutical 49 (22%)
  • Medical 44 (19%)
See all 66 industries →

Stage

  • Series B 58 (26%)
  • Series A 47 (21%)
  • Series C 34 (15%)
  • Series D 19 (8%)
  • Funding Round 18 (8%)
See all 12 stages →

Country

  • United States 107 (47%)
  • France 9 (4%)
  • Switzerland 4 (2%)
  • United Kingdom 4 (2%)
  • The Netherlands 3 (1%)
See all 13 countries →

Team

NameTitleInvestmentsLinksEmail
Jakob Dupont
Jakob Dupont Executive Partner
Executive Partner Total investments: 3
Find email
James Healy
James Healy General Partner & President
General Partner & President Total investments: 25
Find email
Jonathan Leff
Jonathan Leff Executive Partner, Private Equity
Executive Partner, Private Equity Total investments: 3
Find email
Lesley Weber
Lesley Weber San Diego Office Manager & EA
San Diego Office Manager & EA Total investments: 0 Find email
Maha Radhakrishnan
Maha Radhakrishnan Executive Partner
Executive Partner Total investments: 2
Find email
See all 14 team members →

Investments

CompanyDescriptionRoundLinks
Lisata Therapeutics is a clinical-stage pharmaceutical company developing therapies based on clear differentiation and rigorous data applied in areas of high unmet medical need. They focus on the discovery, development, and commercialization of therapies for the treatment of solid tumors and other major diseases. $225M / Post-IPO Equity / Sep 17, 2026
Expedition Therapeutics operates as an unincorporated association. $115M / Series B / Aug 05, 2026
Claris Biotherapeutics develops a topical formulation intended to cure corneal wounds, ulcers, and scars. The formulation creates a recombinant hepatocyte growth factor which accelerates the healing process, providing healthcare providers noninvasive therapeutic treatment. $118M / Series B / Jul 28, 2026
City Therapeutics is a biopharmaceutical company focusing on engineering next-generation small-interfering RNAs (siRNAs) to enhance RNAi-based therapies. The company develops a pipeline of innovative RNAi therapeutics aimed at addressing various disease indications. City Therapeutics prioritizes improving and expanding RNAi technology to achievebetter patient outcomes. The leadership team includes experienced scientists and industry professionals dedicated to advancing the field of RNA interference. $99.5M / Series B / Jun 08, 2026
Coultreon Biopharma is developing best-in-class therapeutics that target clinically validated pathways in immunology and metabolic illnesses.Coultreon Biopharma employs extensive experience in disease biology, drug development, and translational science to identify the optimum treatment approach for addressing underlying illness biology withbest-in-class therapeutics. $125M / Series A / Apr 28, 2026
Aeovian Pharmaceuticals develops and investigates targeted small molecule therapeutics aimed at restoring cellular metabolic quality control to address dysregulated growth and signaling linked to certain rare genetic and age-related conditions. The company’s pipeline centers on compounds that selectively modulate specific biological pathways,including inhibitors designed to influence disease processes associated with neurological dysfunction. Its lead development candidate is a central nervous system-penetrant selective inhibitor being evaluated in clinical trials for refractory seizures related to a genetic disorder, and additional compounds are in earlier stages of investigation for other disease areas. Aeovian Pharmaceuticals also maintains a portfolio of proprietary molecules that engage defined molecular targets to explore potential treatments beyond its program. $55M / Series B / Dec 16, 2025
Expedition Therapeutics operates as an unincorporated association. $165M / Series A / Oct 09, 2025
Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients. $125M / Series D / Sep 30, 2025
Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment. $60M / Series B / Sep 04, 2025
ARTBIO is a clinical-stage radiopharmaceutical biotechnology business that is working to create a new class of alpha radioligand medicines. ARTBIO is changing cancer care by creating a new class of alpha radioligand therapeutics (ART) and the ecosystem that supports. $132M / Series B / Jul 29, 2025
See all 227 investments →

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FAQ

What does Sofinnova Investments invest in?

Sofinnova Investments invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series B and Series A stage. Most of the 227 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Sofinnova Investments invest in?

Sofinnova Investments typically joins rounds of $7.3M–$100M at Series A, $15M–$150M at Series B and $15M–$94M at Series C. These are whole funding-round sizes, not Sofinnova Investments's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Sofinnova Investments took part in.

How do I contact Sofinnova Investments?

Public channels for Sofinnova Investments include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Sofinnova Investments?

The team at Sofinnova Investments includes Jakob Dupont (Executive Partner), James Healy (General Partner & President) and Jonathan Leff (Executive Partner, Private Equity), among 14 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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