Mark Goldstein
Partner @ Builders VC
San Francisco, United States
Mark Goldstein is a seed investor at Builders VC in San Francisco focused on Health Care and Medical. Mark got his start as a full-time operator – co-founding a dozen fintech, SaaS, e-commerce, retail, green tech, online gaming, and music ventures over the past 30 years. Now, Mark's passion is as 'player/coach'. His mission is two-fold: helping America reduce the cost and increase the efficacy of health care via technology, andenabling founders (with deep domain experience in their respective industry) to take on the legacy providers that directly or indirectly are holding back change.Mark is the Founder and Chairman of the Digital Health Hub Foundation, a 501c3 that manages and runs the world's leading health awards show, now held annually at the HLTH Conference in Las Vegas. Each year thousands of companies apply and thousands of judges vote for the best of the best in health and wellness.Mark also previously was an Entrepreneur-in-Residence at Softbank and then at NEA and has made over 150 investments in tech either as an angel or institutional investor.Mark is a graduate of the University of Pennsylvania and has served on its Board of Overseers.
- Total investments:
- 14
- Last investment:
- Lead investor:
- 36%
Last updated:
For AI agents: llms.txt
Industries Mark Goldstein invests in
Stages Mark Goldstein invests in
Countries Mark Goldstein invests in
Contacts
| Type | Contact | Validation |
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| Work email | ||
| Personal email | ||
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Investment Focus
Industry
- Health Care 6 (43%)
- Medical 3 (21%)
- Wellness 3 (21%)
- SaaS 2 (14%)
- mHealth 2 (14%)
Stage
- Seed 6 (43%)
- Series A 4 (29%)
- Convertible Note 2 (14%)
- Series B 1 (7%)
Country
- United States 10 (71%)
- Mexico 1 (7%)
- Argentina 1 (7%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Puna Bio develops biological inputs for agriculture that increase yields, reduce carbon emissions, and restore degraded soil. | $20.3M / Series A / Apr 22, 2025 | ||
| Diagnostikare is a pioneering digital health company in Mexico, dedicated to providing high-quality, accessible care to underserved populations, where over 50 million people lack adequate healthcare. Known for its innovation and trusted by hundreds of thousands of patients, Diagnostikare holds top industry certifications. Through a hybrid modelthat integrates virtual and in-person services, Diagnostikare delivers comprehensive primary care and is strategically positioned to scale impact across Latin America’s growing healthcare market. | Seed / Nov 01, 2022 | ||
| Puna Bio develops biological inputs for agriculture that increase yields, reduce carbon emissions, and restore degraded soil. | $3.7M / Seed / Sep 01, 2022 | ||
| Circle is an AI data management and customer relationship SaaS platform that makes it easier for our customers, health plans, value-based care providers, and brokers to get rewarded for better serving their members. | $6M / Convertible Note / Jun 13, 2022 | ||
| Mendel is a clinical AI platform for life sciences and healthcare organizations that deciphers health data with clinician-like logic. It indexes structured and unstructured data and replaces the complexity of querying with the simplicity of chatting. | $18M / Series A / Jun 07, 2021 | ||
| Conversa enables health systems to virtually engage, monitor and manage patients for chronic care, acute discharge, perioperative, oncology, OBGYN, prevention and wellness, and more. The automated care platform engages patients at high frequency and scale, while triaging to care venues when necessary, optimizing and improving the use of telehealthe-visits, phone calls and in-person consults. Conversa’s suite of COVID-19 Virtual Care Programs is being used by innovative organizations like UCSF Health, Northwell, UNC Health, Prisma Health and University Hospitals to provide symptom checking and triage, provide check-ins with quarantined patients, deliver lab results and screen employees, patients and visitors. | $8M / Series B / Jan 19, 2021 | ||
| Conversa enables health systems to virtually engage, monitor and manage patients for chronic care, acute discharge, perioperative, oncology, OBGYN, prevention and wellness, and more. The automated care platform engages patients at high frequency and scale, while triaging to care venues when necessary, optimizing and improving the use of telehealthe-visits, phone calls and in-person consults. Conversa’s suite of COVID-19 Virtual Care Programs is being used by innovative organizations like UCSF Health, Northwell, UNC Health, Prisma Health and University Hospitals to provide symptom checking and triage, provide check-ins with quarantined patients, deliver lab results and screen employees, patients and visitors. | $12M / Series B / Jun 11, 2020 | ||
| Chi Botanic creates plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesizethe desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural productsWe make plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural products | $950K / Convertible Note / Mar 06, 2020 | ||
| NeuroFlow is a platform to be a resource and asset to the health care provider in their pursuit to get patients better and improve lives. NeuroFlow is a HIPAA-compliant cloud-based platform that empowers health care providers to track, assess, and engage patients using evidence-based practices to support their mental health. The suite of toolssupports remote monitoring and behavioral health integration across the continuum of care, including psychology, primary care, and pain management settings, with the goal of increasing patient engagement and improving compliance. | $7.5M / Series A / Dec 16, 2019 | ||
| Bloomlife is an award winning women’s health company solving the most significant yet underserved global challenges today in maternal health. We are redefining the way maternal care is delivered by combining connected devices with cloud based data analytics to improve access to care, empower women, and provide clinicians with information to moreeffectively screen and manage pregnancy complications. Our goal is to become the leading provider of remote care for expectant women globally. Bloomlife’s approach to managing high risk pregnancies allows obstetricians to more easily screen maternal and fetal risk, educate the patient, and quickly access high risk specialists regardless of a patient’s geography. Our solution represents a marked shift from the way high risk pregnancies have been historically assessed using frequent in person appointments, paper logs, and long referral times. | $5.5M / Seed / Aug 15, 2016 | ||
| See all 14 investments → | |||
Co-Investors
About Builders VC
Builders VC is an early-stage venture capital firm focused on investing where technology meets new business models to modernize antiquated industries including healthcare, agriculture, industrials and real-estate.
Builders VC Contacts
| Name | Phone | Socials | |
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Amit Mehta
General Partner
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Jim Kim
Founder & General Partner
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Mark Goldstein
Partner
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Alex Kinnier
Partner
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Jocelyn Doe
General Partner
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FAQ
What does Mark Goldstein invest in?
Mark Goldstein invests primarily in Health Care, Medical and Wellness startups, most often at Seed and Series A stage. Most of the 14 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
How do I contact Mark Goldstein?
Public channels for Mark Goldstein include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
When did Mark Goldstein last invest?
The most recent investment recorded for Mark Goldstein closed in Apr 2025. Shizune tracks 14 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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