Mark Goldstein
Partner @ Builders VC
San Francisco, United States
Mark Goldstein is a seed investor at Builders VC in San Francisco focused on Health Care and Medical. Mark got his start as a full-time operator – co-founding a dozen fintech, SaaS, e-commerce, retail, green tech, online gaming, and music ventures over the past 30 years. Now, Mark's passion is as 'player/coach'. His mission is two-fold: helping America reduce the cost and increase the efficacy of health care via technology, andenabling founders (with deep domain experience in their respective industry) to take on the legacy providers that directly or indirectly are holding back change.Mark is the Founder and Chairman of the Digital Health Hub Foundation, a 501c3 that manages and runs the world's leading health awards show, now held annually at the HLTH Conference in Las Vegas. Each year thousands of companies apply and thousands of judges vote for the best of the best in health and wellness.Mark also previously was an Entrepreneur-in-Residence at Softbank and then at NEA and has made over 150 investments in tech either as an angel or institutional investor.Mark is a graduate of the University of Pennsylvania and has served on its Board of Overseers.
- Total investments:
- 13
- Last investment:
- Lead investor:
- 31%
Last updated:
For AI agents: llms.txt
Industries Mark Goldstein invests in
Stages Mark Goldstein invests in
Countries Mark Goldstein invests in
Investment Focus
Industry
- Health Care 5 (38%)
- Medical 3 (23%)
- mHealth 3 (23%)
- Wellness 3 (23%)
- SaaS 2 (15%)
Stage
- Seed 6 (46%)
- Series A 3 (23%)
- Convertible Note 2 (15%)
- Series B 1 (8%)
Country
- United States 9 (69%)
- Mexico 1 (8%)
- Argentina 1 (8%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Puna Bio
|
Puna Bio develops biological inputs for agriculture that increase yields, reduce carbon emissions, and restore degraded soil. | $20.3M / Series A / Apr 22, 2025 | |
Diagnostikare
|
Diagnostikare is a pioneering digital health company in Mexico, dedicated to providing high-quality, accessible care to underserved populations, where over 50 million people lack adequate healthcare. Known for its innovation and trusted by hundreds of thousands of patients, Diagnostikare holds top industry certifications. Through a hybrid modelthat integrates virtual and in-person services, Diagnostikare delivers comprehensive primary care and is strategically positioned to scale impact across Latin America’s growing healthcare market. | Seed / Nov 01, 2022 | |
|
Puna Bio
|
Puna Bio develops biological inputs for agriculture that increase yields, reduce carbon emissions, and restore degraded soil. | $3.7M / Seed / Sep 01, 2022 | |
Circle
|
Circle is an AI data management and customer relationship SaaS platform that makes it easier for our customers, health plans, value-based care providers, and brokers to get rewarded for better serving their members. | $6M / Convertible Note / Jun 13, 2022 | |
Mendel.ai
|
Mendel is a clinical AI platform for life sciences and healthcare organizations that deciphers health data with clinician-like logic. It indexes structured and unstructured data and replaces the complexity of querying with the simplicity of chatting. | $18M / Series A / Jun 07, 2021 | |
Conversa Health
|
Conversa enables health systems to virtually engage, monitor and manage patients for chronic care, acute discharge, perioperative, oncology, OBGYN, prevention and wellness, and more. The automated care platform engages patients at high frequency and scale, while triaging to care venues when necessary, optimizing and improving the use of telehealthe-visits, phone calls and in-person consults. Conversa’s suite of COVID-19 Virtual Care Programs is being used by innovative organizations like UCSF Health, Northwell, UNC Health, Prisma Health and University Hospitals to provide symptom checking and triage, provide check-ins with quarantined patients, deliver lab results and screen employees, patients and visitors. | $8M / Series B / Jan 19, 2021 | |
|
Conversa Health
|
Conversa enables health systems to virtually engage, monitor and manage patients for chronic care, acute discharge, perioperative, oncology, OBGYN, prevention and wellness, and more. The automated care platform engages patients at high frequency and scale, while triaging to care venues when necessary, optimizing and improving the use of telehealthe-visits, phone calls and in-person consults. Conversa’s suite of COVID-19 Virtual Care Programs is being used by innovative organizations like UCSF Health, Northwell, UNC Health, Prisma Health and University Hospitals to provide symptom checking and triage, provide check-ins with quarantined patients, deliver lab results and screen employees, patients and visitors. | $12M / Series B / Jun 11, 2020 | |
Chi Botanic
|
Chi Botanic creates plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesizethe desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural productsWe make plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural products | $950K / Convertible Note / Mar 06, 2020 | |
Bloomlife
|
Bloomlife is a women’s health company solving the most significant yet underserved global challenges today in maternal health. We combine connected devices with data analytics to increase access to care, provide personalized feedback to moms, and help doctors earlier predict and manage pregnancy complications. At the center of our solution is aprenatal wearable that tracks critical health parameters of maternal and fetal health. By addressing modifiable risk factors, detecting abnormalities, and predicting adverse events Bloomlife aims to ensure every family gets a healthy start. | $4M / Seed / Aug 15, 2016 | |
FairClaims
|
FairClaims is the most efficient, cost-effective online dispute resolution platform for enterprise. | $285K / Seed / Jul 31, 2016 | |
| See all 13 investments → | |||
Co-Investors
SOSV
6 deals together
Northwell Ventures
4 deals together
Alumni Ventures
2 deals together
At One Ventures
2 deals together
BootstrapLabs
2 deals together
Genesis Merchant Capital
2 deals together
About Builders VC
Builders VC is an early-stage venture capital firm focused on investing where technology meets new business models to modernize antiquated industries including healthcare, agriculture, industrials and real-estate.
Builders VC Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Amit Mehta
General Partner
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Jim Kim
Founder & General Partner
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Mark Goldstein
Partner
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Alex Kinnier
Partner
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Jocelyn Doe
General Partner
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FAQ
What does Mark Goldstein invest in?
Mark Goldstein invests primarily in Health Care, Medical and mHealth startups, most often at Seed and Series A stage. Most of the 13 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
When did Mark Goldstein last invest?
The most recent investment recorded for Mark Goldstein closed in Apr 2025. Shizune tracks 13 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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