Main Street Advisors
VC Fund
Chicago, United States
Main Street Advisors is a VC fund in Chicago focused on Internet and Health Care. Main Street Advisors, Inc., an investment and financial advisory company.
- Total investments:
- 9
- Last investment:
- Lead investor:
- 11%
Last updated:
For AI agents: llms.txt
Industries Main Street Advisors invests in
Stages Main Street Advisors invests in
Countries Main Street Advisors invests in
Round sizes
Round size
- Series A
- $9M–$48M
- Series B
- $8.2M–$61M
Investment Focus
Industry
- Internet 4 (44%)
- Health Care 3 (33%)
- Software 2 (22%)
- Information Technology 2 (22%)
- iOS 1 (11%)
Stage
- Series B 3 (33%)
- Seed 2 (22%)
- Series A 2 (22%)
- Series C 1 (11%)
- Series D 1 (11%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Kate Farms
|
Kate Farms offers nutritionally advanced, plant-based tube feeding, and enteral formulas that are well-tolerated by patients. Free of common allergens, including soy, dairy, and corn, clinicians report patients have experienced decreased symptoms of GI intolerance, improved weight or linear growth, and overall improved nutritional status. KateFarms is now the #1 plant-based enteral formula on the market. They’re gaining a better understanding of the role nutrition has on health, both in the management of care and direct therapeutic impact. Ingredients matter and our formulas are designed to deliver outcomes that matter. They pair leading-edge science and technologies with ingredients from nature in unique formulations that work with the bodies. This combination offers the potential for significant improvements to health and to the practice of healthcare. Today doctors, dietitians, parents, caregivers, and those with medical and dietary needs are empowered with the choice of a new formula. It’s the nourishment that makes them feel good because everyone deserves nothing less. | $75M / Series C / Sep 19, 2022 | |
Mahana Therapeutics
|
Mahana Therapeutics develops digital treatments for people living with chronic health conditions that are designed to provide physical and psychological support that will be clinically proven to help patients feel better. | $61M / Series B / Aug 11, 2021 | |
|
Kate Farms
|
Kate Farms offers nutritionally advanced, plant-based tube feeding, and enteral formulas that are well-tolerated by patients. Free of common allergens, including soy, dairy, and corn, clinicians report patients have experienced decreased symptoms of GI intolerance, improved weight or linear growth, and overall improved nutritional status. KateFarms is now the #1 plant-based enteral formula on the market. They’re gaining a better understanding of the role nutrition has on health, both in the management of care and direct therapeutic impact. Ingredients matter and our formulas are designed to deliver outcomes that matter. They pair leading-edge science and technologies with ingredients from nature in unique formulations that work with the bodies. This combination offers the potential for significant improvements to health and to the practice of healthcare. Today doctors, dietitians, parents, caregivers, and those with medical and dietary needs are empowered with the choice of a new formula. It’s the nourishment that makes them feel good because everyone deserves nothing less. | $9M / Seed / Jan 01, 2021 | |
Hyperice
|
HyperIce is a recovery and movement enhancement technology company specializing in vibration, percussion, and thermal technology. Its technology is used by the athletes in professional and collegiate training rooms and fitness facilities globally.The company is driven by a mission to provide everyone with the innovative technology in acceleratingrecovery time, preventing injury, and enhancing the body’s ability to move efficiently. HyperIce was founded in 2010 by Anthony Katz. | $47.8M / Series A / Oct 08, 2020 | |
NTWRK
|
NTWRK is the definitive Video Commerce platform developed specifically for Gen Z and Millennials. NTWRK's innovative model of daily exclusive product drops, live videos, celebrity talent, native purchases and social distribution creates a high energy and wide-reaching experience for brands and users. NTWRK was launched in October 2018. Sincelaunch, the platform has experienced meteoric growth and has received investments from some of the most successful entrepreneurs, brands and influential entertainers in the world including Live Nation, Foot Locker and Main Street Advisors, whose investors include Jimmy Iovine and LeBron James. | Seed / May 01, 2018 | |
EVERFI
|
EVERFI operates a network for online education in off-curriculum, but highly valuable content areas such as financial literacy, student loan management, digital literacy, substance abuse prevention, and other key life skills for the 21st-century student. The company's software-as-a-service platform is designed to provide a highly engagingexperience for students and features the latest technology and instructional design, including rich media, high-definition video, 3D simulations, and social networking. EVERFI partners with more than 7,000 schools, colleges, and universities in all 50 states. | $190M / Series D / Apr 26, 2017 | |
BeautyCon
|
Beautycon Media is THE global community for content creators, celebrities, fans, and brands for fashion, beauty and lifestyle. Their mission is to challenge traditional beauty standards and redefine what beauty means. They embrace "imperfections" and the nontraditional—both inside and out, with a focus on featuring innovators of allages, races, and identities. They’re a diverse global community of content creators, celebrities, fans, and brands that come together to celebrate using make-up as a tool for self-expression and sharing your enthusiasm with the world. They create meaningful connections for these communities through our Beautycon Festivals, Beautycon Box, and Beautycon Digital platforms. | $9M / Series A / Mar 20, 2017 | |
ATTN:
|
ATTN: is a content network that helps young people understand and impact the world around them. It was launched in June 2014. | $18M / Series B / Feb 19, 2016 | |
Reliacast
|
Reliacast alone offers the best solution for Webcasting to deliver on its full potential. Their audience measurement, management and control technologies are enabling a whole new breed of compelling Webcasting services. | $8.2M / Series B / Mar 28, 2000 |
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FAQ
What does Main Street Advisors invest in?
Main Street Advisors invests primarily in Internet, Health Care and Software startups, most often at Series B and Seed stage. Most of the 9 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Main Street Advisors's check size?
Main Street Advisors typically joins rounds of $9M–$48M at Series A and $8.2M–$61M at Series B. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Main Street Advisors participates in.
When did Main Street Advisors last invest?
The most recent investment recorded for Main Street Advisors closed in Sep 2022. Shizune tracks 9 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Sep 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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