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Joe McCann, Founder, CEO, and CIO at Asymmetric

Joe McCann

Founder, CEO, and CIO @ Asymmetric

San Francisco, United States

Joe McCann is a seed investor at Asymmetric in San Francisco focused on Blockchain and Cryptocurrency. Joe McCann is the Founder, CEO, and CIO of Asymmetric, a contemporary digital assets investment firm. With over 24 years of experience working on Wall Street to Silicon Valley and with skills ranging from systematic and quantitative trading to fundraising and running a venture-backed, open-source enterprise software company, McCann's perspective on technology and finance is rather unique. McCann is a frequent speaker on the global conference circuit, actively promoting emerging technologies and relevant business use cases to bring pragmatism to futurism. Most recently, McCann was a Senior Director at Microsoft in the Cloud and AI organization, focusing on incubations, M&A, and startups. McCann also ran Quantitative and Systematic Trading for Cryptocurrencies at Passport Capital, a San Francisco-based hedge fund. Before that, McCann was the Founder and CEO of NodeSource, The Node.js Company, the most popular and widely adopted open source project of the last decade. McCann is also an advisor to a handful of companies like Dharma (a decentralized finance app on Ethereum, acquired by OpenSea), Voltage (Bitcoin lightning nodes-as-a-service), and Zebec (a money-streaming protocol on Solana) and is frequently mentioned in publications ranging from TechCrunch to Forbes and the Wall Street Journal.

Total investments:
18
Last investment:
Lead investor:
11%

Last updated:

Industries Joe McCann invests in

BlockchainCryptocurrencyGamingSoftwareArtificial Intelligence

Stages Joe McCann invests in

SeedAngelPre-SeedSeries A

Countries Joe McCann invests in

United StatesSingaporeCanadaIsraelSwitzerland

Round sizes

Seed $1.9M–$14M

Contacts

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Round size

Seed
$1.9M–$14M

Investment Focus

Industry

  • Blockchain 9 (50%)
  • Cryptocurrency 7 (39%)
  • Gaming 3 (17%)
  • Software 3 (17%)
  • Artificial Intelligence 3 (17%)
See all 27 industries →

Stage

  • Seed 15 (83%)
  • Angel 1 (6%)
  • Pre-Seed 1 (6%)
  • Series A 1 (6%)

Country

  • United States 11 (61%)
  • Singapore 2 (11%)
  • Canada 1 (6%)
  • Israel 1 (6%)
  • Switzerland 1 (6%)

Investments

CompanyDescriptionRoundLinks
Rebel Audio is an agentic podcast platform driven by AI that aims to modernize the production, distribution, and monetization of audio. Rebel Audio is a comprehensive system that simplifies production, publication, analytics, and revenue generation for creators, networks, and media organizations. Series A / Oct 08, 2026
Ryder develops the Ryder One hardware wallet to provide an easy and secure way for users to control their cryptocurrency holdings offline. The wallet uses simple tap-to-pay technology for fast setup and transaction authorization, combined with an EAL6+ Secure Element for protection against digital and physical attacks. $3.2M / Seed / Oct 17, 2025
Arcium is a parallelized confidential computing network that provides trustless, verifiable and efficient encrypted computation. Arcium implements Multiparty Computation Execution Environments (MXEs) that combine MPC, homomorphic encryption, zero-knowledge proofs, and more to enable computation on encrypted data. $2M / Angel / Mar 27, 2025
Ranger Finance is perpetual DEX aggregator that offers deep aggregated liquidity, smart order routing, and comprehensive data insight. $1.9M / Seed / Jan 24, 2025
GolfN is a cutting-edge platform that rewards real-world golf play with digital benefits. Players gain points for their on-course achievements and involvement. Additionally, GolfN introduces digital trade cards, which provide a collectible and interactive element. $1.3M / Pre-Seed / Jun 25, 2024
Saturn is a decentralized Bitcoin exchange that enhances peer-to-peer non-custodial orderbooks and provides a secure trading experience. $800K / Seed / Feb 26, 2024
Cube Group is a hybrid CEX-DEX digital asset marketplace that addresses the challenges of traditional centralized exchanges and decentralized finance platforms. The company provides a user-centric design, radical transparency, safety, and liquidity, with features like multi-party compute, on-chain settlement, proof-of-reserves, and multi-chainsupport. Its vaults represent users' balances on their respective layer-one blockchains, offering transparent liquidation standards and criteria for derivatives and margin trading. The platform also standardizes market data and order sessions, allowing seamless onboarding for market participants through web interfaces for trading. $9M / Seed / Oct 24, 2023
Random Games is a development studio spearheading concept in videogames with a community empowerment, blockchain technology. $7.6M / Seed / Sep 20, 2022
Spice AI is creating technology to make artificial intelligence and machine learning more accessible to developers. Building intelligent apps that leverage AI is still way too hard, even for advanced developers. Spice AI's mission is to make this as easy as creating a modern web page. This mission is in service of our vision to makequality-of-life improving AI accessible to all.Founded in June 2021, Spice AI, Inc. is a Seattle, Washington headquartered technology startup building developer-focused AI. Spice AI was founded by ex-Microsoft and GitHub engineers, with over 20 years of combined experience in distributed and cloud computing. $13.5M / Seed / Sep 07, 2022
Clockwork schedules tasks and automates on-chain workflows directly with the Solana validator network. $4M / Seed / Aug 30, 2022
See all 18 investments →

Co-Investors

Asymmetric

About Asymmetric

VC Fund

Asymmetric is a technology company with a fund mandate, founded by solo GP and Investment Manager, Joe McCann

Asymmetric Contacts

NameEmailPhoneSocials
Dan Held
Dan Held General Partner
Joe McCann
Joe McCann Founder, CEO, and CIO
Joe McCann
Joe McCann Founder, CEO, and CIO

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FAQ

What does Joe McCann invest in?

Joe McCann invests primarily in Blockchain, Cryptocurrency and Gaming startups, most often at Seed and Angel stage. Most of the 18 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Joe McCann invest in?

Joe McCann typically joins rounds of $1.9M–$14M at Seed. These are whole funding-round sizes, not Joe McCann's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Joe McCann took part in.

How do I contact Joe McCann?

Public channels for Joe McCann include LinkedIn, X (Twitter) and Facebook. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Joe McCann last invest?

The most recent investment recorded for Joe McCann closed in Oct 2026. Shizune tracks 18 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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