Jacob Vogelstein
Co-Founder and Managing Partner @ Catalio Capital Management
Bethesda, United States
Jacob Vogelstein is a Co-Founder and Managing Partner at Catalio Capital Management, LP. He attended The Johns Hopkins University School of Medicine.
- Total investments:
- 12
- Last investment:
- Lead investor:
- 58%
Last updated:
For AI agents: llms.txt
Industries Jacob Vogelstein invests in
Stages Jacob Vogelstein invests in
Countries Jacob Vogelstein invests in
Contacts
| Type | Contact | Validation |
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| Work email | ||
| Personal email | ||
| Work phone | ||
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Investment Focus
Industry
- Biotechnology 7 (58%)
- Health Care 5 (42%)
- Therapeutics 5 (42%)
- Artificial Intelligence 3 (25%)
- Medical 2 (17%)
Stage
- Series A 5 (42%)
- Series B 3 (25%)
- Venture - Series Unknown 2 (17%)
- Series D 1 (8%)
- Funding Round 1 (8%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Evvy is a developer of at-home vaginal microbiome tests to close the gender health gap and improve female health. It uses metagenomic sequencing to understand symptoms and risks for critical health challenges, and get personalized reports. | $40M / Series B / Sep 15, 2026 | ||
| Flourish Labs is a research and development company that combines certified humans, technology, and AI to provide every employee with a dedicated coach. The company builds AI-powered platforms for peer mental health support, focused on making mental health care accessible. | $500M / Series A / Jun 04, 2026 | ||
| The Iambic AI-driven platform was created to address the most challenging design problems in drug discovery, leveraging technology innovations such as Enchant, a multi-modal transformer model that predicts clinical outcomes from the earliest stages of discovery, and NeuralPLexer, the best-in-class predictor of protein and protein-ligand structures.The integration of physics principles into the platform’s AI architectures improves data efficiency and allows molecular models to venture widely across the space of possible chemical structures. The platform enables identification of novel chemical modalities for engaging difficult-to-address biological targets, discovery of defined product profiles that optimize therapeutic window, and multi-parameter optimization for highly differentiated development candidates. Through close integration of AI-generated molecular designs with automated experimental execution, Iambic completes design-make-test cycles on a weekly cadence. | $127.8M / Nov 10, 2025 | ||
| Syndeio Biosciences is a clinical-stage biotechnology company focused on developing therapies to restore and enhance synaptic health in central nervous system (CNS) disorders. | $90M / Venture - Series Unknown / May 27, 2025 | ||
| Clasp Therapeutics offers to reach of immuno-oncology with novel precision medicines that enable the immune system to identify and specifically destroy hard-to-treat tumors bearing common driver mutations, regardless of tumor type. | $150M / Series A / Mar 20, 2024 | ||
| NextPoint Therapeutics develops medications to expand the benefit of immunotherapies to cancer patients. The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems to find and destroy cancer cells. | $42.5M / Series B / Feb 14, 2024 | ||
| The Iambic AI-driven platform was created to address the most challenging design problems in drug discovery, leveraging technology innovations such as Enchant, a multi-modal transformer model that predicts clinical outcomes from the earliest stages of discovery, and NeuralPLexer, the best-in-class predictor of protein and protein-ligand structures.The integration of physics principles into the platform’s AI architectures improves data efficiency and allows molecular models to venture widely across the space of possible chemical structures. The platform enables identification of novel chemical modalities for engaging difficult-to-address biological targets, discovery of defined product profiles that optimize therapeutic window, and multi-parameter optimization for highly differentiated development candidates. Through close integration of AI-generated molecular designs with automated experimental execution, Iambic completes design-make-test cycles on a weekly cadence. | $100M / Series B / Oct 03, 2023 | ||
| Haystack Oncology, an oncology company, uses the most recent circulating tumor DNA detection technology to enhance the diagnosis of minimum residual disease and provide superior therapy decision-making information. | $56M / Series A / Nov 16, 2022 | ||
| Pheast Therapeutics is a cancer immunotherapy company focused on developing novel checkpoint therapies to harness the innate immune system in the fight against cancer. It was founded in 2020 and headquartered in Palo Alto, California. | $76M / Series A / Apr 26, 2022 | ||
| The Iambic AI-driven platform was created to address the most challenging design problems in drug discovery, leveraging technology innovations such as Enchant, a multi-modal transformer model that predicts clinical outcomes from the earliest stages of discovery, and NeuralPLexer, the best-in-class predictor of protein and protein-ligand structures.The integration of physics principles into the platform’s AI architectures improves data efficiency and allows molecular models to venture widely across the space of possible chemical structures. The platform enables identification of novel chemical modalities for engaging difficult-to-address biological targets, discovery of defined product profiles that optimize therapeutic window, and multi-parameter optimization for highly differentiated development candidates. Through close integration of AI-generated molecular designs with automated experimental execution, Iambic completes design-make-test cycles on a weekly cadence. | $53M / Series A / Jul 14, 2021 | ||
| See all 12 investments → | |||
Co-Investors
Catalio Capital Management is a venture capital firm that invests in breakthrough biomedical technology companies. It was created by George Petrocheilos and Dr. Jacob Vogelstein in 2020.
Catalio Capital Management Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Ben Snedeker
Partner and Co-Head Public Equities
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George Petrocheilos
Co-Founder & Managing Partner
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Isaac Ro
Partner
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Jacob Vogelstein
Co-Founder and Managing Partner
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Kenan Turnacioglu
General Partner
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FAQ
What does Jacob Vogelstein invest in?
Jacob Vogelstein invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 12 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
How do I contact Jacob Vogelstein?
Public channels for Jacob Vogelstein include LinkedIn. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
When did Jacob Vogelstein last invest?
The most recent investment recorded for Jacob Vogelstein closed in Sep 2026. Shizune tracks 12 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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