Hank Plain
Partner @ Morgenthaler Ventures
Menlo Park, United States
Hank Plain is a Series C investor at Morgenthaler Ventures in Menlo Park focused on Medical and Health Care. Hank Plain is the Partner of Morgenthaler Ventures.
- Total investments:
- 20
- Last investment:
- Lead investor:
- 5%
Last updated:
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Industries Hank Plain invests in
Stages Hank Plain invests in
Countries Hank Plain invests in
Investment Focus
Industry
- Medical 8 (40%)
- Health Care 8 (40%)
- Medical Device 8 (40%)
- Therapeutics 3 (15%)
- Biopharma 2 (10%)
Stage
- Series C 5 (25%)
- Series B 4 (20%)
- Series D 4 (20%)
- Series E 1 (5%)
- Funding Round 1 (5%)
Country
- United States 8 (40%)
- France 1 (5%)
Investments
| Company | Description | Round | Links |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $115M / Series D / Aug 11, 2025 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $80M / Jan 19, 2023 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $80M / Series C / Jan 19, 2023 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $64M / Jan 27, 2021 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $64M / Series B / Jan 27, 2021 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $15.7M / Sep 18, 2019 | |
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Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases. Nuvaira is currently working on a novel catheter-based system that has the potential to improve lung function, exercise capacity, and quality of life for patients with chronic obstructive pulmonary disease.It was founded in 2008and headquartered in Minneapolis, Minnesota. | $79M / Series E / Feb 11, 2019 | |
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Earlens is a privately held medical technology company committed to transforming the hearing experience for millions of people who suffer from hearing loss.The company has developed the Earlens Contact Hearing Solution, which directly activates natural hearing, delivering the broadest bandwidth available today and superior sound quality. Thisrevolutionary, non-surgical hearing solution uses a small lens to vibrate the eardrum, replicating the natural hearing process. The Earlens Contact Hearing Solution received FDA clearance in 2019 for a second generation of the Earlens technology. Unlike traditional hearing aids, which are in effect tiny speakers that simply turn up the volume on air conducted sound, the Earlens Contact Hearing Solution™ is the world’s first to deliver sound directly to the eardrum. | $87M / Series D / Oct 22, 2018 | |
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Claret Medical, Inc. develops a series of cerebral vascular protection systems for transcatheter aortic valve implantation, surgical, and other interventional procedures. The company’s products include Claret Medical Montage, a dual filter system and percutaneously delivered embolic protection device to capture and remove debris disloged duringvascular procedures; and small (6F) catheters that are inserted into the patient's right arm to protect the patient’s brain during interventional procedures where embolic debris might be released. It offers its products for use as an embolic protection system to capture and remove embolic material (thrombus/debris) that may enter the cerebral vascular system during endovascular procedures. The company was incorporated in 2009 and is based in Santa Rosa, California. | $14.5M / Series C / Oct 23, 2017 | |
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SetPoint Medical is a company that developed a device-based therapeutic approach for treating rheumatoid arthritis. The company's product, the SetPoint System, is a small, wireless implantable device that stimulates the vagus nerve to reduce inflammation. The therapy is an approach for adults with active rheumatoid arthritis who have notresponded to other treatments. | $30M / Series D / Aug 28, 2017 | |
| See all 20 investments → | |||
Co-Investors
About Morgenthaler Ventures
Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.
Morgenthaler Ventures Contacts
| Name | Phone | Socials | |
|---|---|---|---|
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Bob Pavey
Partner
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Hank Plain
Partner
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Bridget Odorcic
Operations & Fund Compliance Manager
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Ching Wu
VP of Investor Relations & Marketing
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Gary Little
Partner
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FAQ
What does Hank Plain invest in?
Hank Plain invests primarily in Medical, Health Care and Medical Device startups, most often at Series C and Series B stage. Most of the 20 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
When did Hank Plain last invest?
The most recent investment recorded for Hank Plain closed in Aug 2025. Shizune tracks 20 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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