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Francesco De Rubertis, Partner at Index Ventures

Francesco De Rubertis

Partner @ Index Ventures

Geneva, Switzerland

Francesco De Rubertis is a Series A investor at Index Ventures in Geneva focused on Biotechnology and Pharmaceutical. Francesco De Rubertis is based out of Geneva, Geneve and is the Co Founder & Partner of Medicxi. Francesco previously worked at Index Ventures as a partner. Francesco De Rubertis attended the University of Geneva.

Total investments:
21
Last investment:
Lead investor:
38%

Last updated:

Industries Francesco De Rubertis invests in

BiotechnologyPharmaceuticalHealth CareMedicalTherapeutics

Stages Francesco De Rubertis invests in

Series ASeries BSeedSeries CPre-Seed

Countries Francesco De Rubertis invests in

United StatesChinaSpainIrelandSwitzerland

Round sizes

Seed $1.2M–$100MSeries A $11M–$140MSeries B $13M–$132M

Contacts

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Round size

Seed
$1.2M–$100M
Series A
$11M–$140M
Series B
$13M–$132M

Investment Focus

Industry

  • Biotechnology 9 (43%)
  • Pharmaceutical 5 (24%)
  • Health Care 4 (19%)
  • Medical 3 (14%)
  • Therapeutics 3 (14%)
See all 13 industries →

Stage

  • Series A 6 (29%)
  • Series B 5 (24%)
  • Seed 4 (19%)
  • Series C 2 (10%)
  • Pre-Seed 1 (5%)
See all 7 stages →

Country

  • United States 5 (24%)
  • China 1 (5%)
  • Spain 1 (5%)
  • Ireland 1 (5%)
  • Switzerland 1 (5%)

Investments

CompanyDescriptionRoundLinks
D3 Bio is a globally focused biotechnology company focusing on developing and registration of innovative medicines in oncology and immunology. At D3 Bio, our new medicine development approach is fundamentally differentiated. We do not just only start with science in the lab. First, we pinpoint the greatest unmet patient and market needs – whereexisting standard-of-care approaches yield unsatisfactory clinical outcomes. Then we take those insights into the lab to guide the identification of fit for purpose science and technology and define our drug development path. $108M / Series B / Dec 09, 2025
Ottimo Pharma is a private biotechnology company dedicated to enhancing cancer treatment outcomes and minimizing the overall healthcare burden. $140M / Series A / Dec 19, 2024
Ottimo Pharma is a private biotechnology company dedicated to enhancing cancer treatment outcomes and minimizing the overall healthcare burden. Seed / Oct 28, 2024
D3 Bio is a globally focused biotechnology company focusing on developing and registration of innovative medicines in oncology and immunology. At D3 Bio, our new medicine development approach is fundamentally differentiated. We do not just only start with science in the lab. First, we pinpoint the greatest unmet patient and market needs – whereexisting standard-of-care approaches yield unsatisfactory clinical outcomes. Then we take those insights into the lab to guide the identification of fit for purpose science and technology and define our drug development path. $62M / Series A / Apr 08, 2024
Alys Pharmaceuticals engages in immuno-dermatology services. The company is reshaping the treatment landscape through advanced scientific innovations and a strong research and development-focused multi-platform pipeline. Alys emerged as a result of the strategic aggregation of 6 asset-centric companies backed by Medicxi. $100M / Seed / Feb 12, 2024
Aldena Therapeutics Aldena Therapeutics
Aldena Therapeutics is a private biotech startup that invented siRNA-based treatments for dermatological conditions. $30M / Series A / Mar 16, 2023
Velada is an app that helps users find the ideal restaurant for any occasion by utilizing data to provide personalized recommendations. Tjey also have a proprietary algorithm that uses data from its users' preferences and app behavior to make personalized recommendations, making Velada the first smart restaurant guide. However, without an appor resource that provides a dedicated local guide, travelers frequently find themselves in tourist traps when it comes to their culinary experience. $1.2M / Seed / Oct 05, 2022
Velada is an app that helps users find the ideal restaurant for any occasion by utilizing data to provide personalized recommendations. Tjey also have a proprietary algorithm that uses data from its users' preferences and app behavior to make personalized recommendations, making Velada the first smart restaurant guide. However, without an appor resource that provides a dedicated local guide, travelers frequently find themselves in tourist traps when it comes to their culinary experience. $1.1M / Pre-Seed / Oct 05, 2022
Rivus Pharmaceuticals operates as a biopharmaceutical company dedicated to improving cardio-metabolic health. Rivus Pharmaceuticals is dedicated to improving cardio-metabolic health by developing controlled metabolic accelerators (CMAs) that address the underlying metabolic risk factors for cardiovascular mortality and morbidity. $132M / Series B / Sep 22, 2022
Rivus Pharmaceuticals operates as a biopharmaceutical company dedicated to improving cardio-metabolic health. Rivus Pharmaceuticals is dedicated to improving cardio-metabolic health by developing controlled metabolic accelerators (CMAs) that address the underlying metabolic risk factors for cardiovascular mortality and morbidity. $35M / Series A / Jul 20, 2021
See all 21 investments →

Co-Investors

Index Ventures

About Index Ventures

VC Fund · San Francisco, United States

Index Ventures is a venture capital company that provides investment capital and strategic support to early-stage and growth-stage technology enterprises across sectors such as software, fintech, healthcare, and consumer services. It engages with entrepreneurial teams to assess business models, support scaling efforts, and provide guidance through successive development phases. The company’s services include sourcing investment opportunities, conducting due diligence, structuring financing deals, and offering ongoing advisory interactions with portfolio founders. Index Ventures also maintains a network of industry relationships and resources aimed at facilitating connections between founders, investors, and market opportunities. Its focus spans from initial seed rounds through later financing stages to help portfolio companies pursue expansion and market entry efforts.

Index Ventures Contacts

NameEmailPhoneSocials
Gerald Rimer
Gerald Rimer Team Member
Hannah Seal
Hannah Seal Principal/Partner
Jan Hammer
Jan Hammer Investor & Partner
Julia Andre
Julia Andre Principal/Partner

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FAQ

What does Francesco De Rubertis invest in?

Francesco De Rubertis invests primarily in Biotechnology, Pharmaceutical and Health Care startups, most often at Series A and Series B stage. Most of the 21 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Francesco De Rubertis invest in?

Francesco De Rubertis typically joins rounds of $1.2M–$100M at Seed, $11M–$140M at Series A and $13M–$132M at Series B. These are whole funding-round sizes, not Francesco De Rubertis's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Francesco De Rubertis took part in.

How do I contact Francesco De Rubertis?

Public channels for Francesco De Rubertis include LinkedIn and X (Twitter). For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Francesco De Rubertis last invest?

The most recent investment recorded for Francesco De Rubertis closed in Dec 2025. Shizune tracks 21 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Nov 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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