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Longitude Capital, VC Fund

Longitude Capital

VC Fund

Menlo Park, United States

Longitude Capital is a VC fund in Menlo Park focused on Health Care and Biotechnology. Longitude Capital specializes in making venture growth investments in biotechnology and medical technology companies that seek to improve clinical outcomes, enhance the quality of life, and/or reduce system costs. They invest in both privately held and publicly traded life science companies through a variety of investment approaches. Since2006, Longitude Capital has raised over $1.2 billion across three funds and demonstrated an ability to source, manage and exit attractive investments across multiple market cycles.Their venture growth strategy is rooted in building a balanced portfolio of clinical-stage and commercial-stage companies with clinically de-risked assets, favorable valuations relative to risk profile, and attractive expected returns within three to five years from the initial investment.Longitude Capital seeks to identify new investment opportunities by tapping into their broad network of industry relationships or through the execution of intensive thematic research into emerging therapeutic areas or industry sub-sectors. They utilize a variety of investment structures, including traditional venture capital, asset spin-outs, recapitalizations, PIPEs, open market purchases, royalties, and other equity and equity-linked instruments.

Total investments:
149
Last investment:
Lead investor:
35%
Fund size:
$50M
Last fund:

Last updated:

Industries Longitude Capital invests in

Health CareBiotechnologyMedicalTherapeuticsPharmaceutical

Stages Longitude Capital invests in

Series BSeries ASeries CSeries DFunding Round

Countries Longitude Capital invests in

United StatesIrelandCanadaSwitzerlandFrance

Round sizes

Series A $17M–$85MSeries B $15M–$117MSeries C $30M–$175M

Contacts

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Round size

Series A
$17M–$85M
Series B
$15M–$117M
Series C
$30M–$175M

Investment Focus

Industry

  • Health Care 67 (45%)
  • Biotechnology 59 (40%)
  • Medical 31 (21%)
  • Therapeutics 31 (21%)
  • Pharmaceutical 27 (18%)
See all 36 industries →

Stage

  • Series B 31 (21%)
  • Series A 28 (19%)
  • Series C 24 (16%)
  • Series D 12 (8%)
  • Funding Round 7 (5%)
See all 13 stages →

Country

  • United States 80 (54%)
  • Ireland 4 (3%)
  • Canada 2 (1%)
  • Switzerland 2 (1%)
  • France 1 (1%)
See all 7 countries →

Team

NameTitleInvestmentsLinksEmail
Amar Patel
Amar Patel Associate
Associate Total investments: 0
Find email
Brian Liu
Brian Liu Principal; Vice President
Principal; Vice President Total investments: 3
Find email
David Hirsch
David Hirsch Managing Director
Managing Director Total investments: 13
Find email
Juliet Tammenoms Bakker
Juliet Tammenoms Bakker Co-Founder and Managing Director
Co-Founder and Managing Director Total investments: 13
Find email
Karthik Bolisetty
Karthik Bolisetty Associate
Associate Total investments: 0
Find email
See all 12 team members →

Investments

CompanyDescriptionRoundLinks
Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience. $275M / Post-IPO Equity / Jul 27, 2026
cAMPfield Therapeutics is a biotechnology company that specializes on exploration and development activities of therapeutic solutions. $180M / Series A / May 20, 2026
AirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions. $200M / Series A / Jan 09, 2026
Ventaris Surgical is a medical equipment company that provides surgical instruments to specialists. $30.7M / Series A / Jan 09, 2026
Veradermics is a dermatology-focused biopharmaceutical company that develops treatments for common skin and hair conditions. Its lead drug candidate, VDPHL01, is an extended-release oral minoxidil being tested in Phase 3 clinical trials for pattern hair loss in both women and men. The company also has pipeline programs targeting conditions such ascommon warts, molluscum contagiosum, and atopic dermatitis. $150M / Series C / Oct 16, 2025
Cohere Health is a healthcare technology company, focused on improving the efficiency and effectiveness of healthcare delivery. Cohere Health aims to simplify the complexities of the healthcare system by leveraging technology to streamline processes, enhance communication, and ultimately improve patient outcomes. The company may provide solutionsto various stakeholders in the healthcare ecosystem, including patients, providers, and payers. $90M / Series C / May 14, 2025
CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases. $100M / Post-IPO Equity / May 12, 2025
MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas. $65M / Series F / Mar 12, 2025
Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders. $65M / Series A / Jan 28, 2025
FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices. Jan 07, 2025
See all 149 investments →

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FAQ

What does Longitude Capital invest in?

Longitude Capital invests primarily in Health Care, Biotechnology and Medical startups, most often at Series B and Series A stage. Most of the 149 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Longitude Capital's check size?

Longitude Capital typically joins rounds of $17M–$85M at Series A, $15M–$117M at Series B and $30M–$175M at Series C. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Longitude Capital participates in.

How do I contact Longitude Capital?

Public channels for Longitude Capital include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Longitude Capital?

The team at Longitude Capital includes Amar Patel (Associate), Brian Liu (Principal; Vice President) and David Hirsch (Managing Director), among 12 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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