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Eric Lefkofsky, Co-founder & Managing Partner at Lightbank

Eric Lefkofsky

Co-founder & Managing Partner @ Lightbank

Chicago, United States

Eric Lefkofsky is a seed investor at Lightbank in Chicago focused on E-Commerce and Mobile. Eric Lefkofsky is the Founder and CEO of Tempus. He previously worked at Echo Global Logistics as a Founder. Eric Lefkofsky attended the University of Michigan Law School.

Total investments:
88
Last investment:
Lead investor:
30%

Last updated:

Industries Eric Lefkofsky invests in

E-CommerceMobileSoftwareInternetApps

Stages Eric Lefkofsky invests in

SeedSeries AFunding RoundSeries BSeries C

Countries Eric Lefkofsky invests in

United StatesUnited KingdomCanadaFranceIsrael

Contacts

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Investment Focus

Industry

  • E-Commerce 20 (23%)
  • Mobile 17 (19%)
  • Software 13 (15%)
  • Internet 8 (9%)
  • Apps 7 (8%)
See all 133 industries →

Stage

  • Seed 32 (36%)
  • Series A 19 (22%)
  • Funding Round 13 (15%)
  • Series B 7 (8%)
  • Series C 5 (6%)
See all 10 stages →

Country

  • United States 64 (73%)
  • United Kingdom 3 (3%)
  • Canada 2 (2%)
  • France 1 (1%)
  • Israel 1 (1%)

Investments

CompanyDescriptionRoundLinks
Inflow delivers payment solutions that integrate affordability, efficiency, innovation, and tailored service. $1.1M / Pre-Seed / Apr 21, 2025
Ohana is a company that allows users to find short-term housing and roommates. $3M / Seed / Jun 17, 2024
Basket is an AI-powered shopping companion transforming online retail into an agentic, ambient experience. By capturing SKU-level purchase intent across 300k+ users, Basket delivers personalised discovery, instant cashback, and automated savings through its universal shopping assistant. Acting as the consumer’s shopping OS, Basket unifieswishlisting, price comparison, gifting, and checkout into one seamless journey, redefining how people shop and how retailers connect with intent-driven audiences. $2.8M / Seed / Oct 26, 2021
Leap enables brands to deploy modern, immersive retail stores that drive growth and acquire customers. By leveraging millions of data points and a platform strategy, Leap makes physical retail more productive and less risky for brands. Its platform also follows a technology-enabled approach and includes all aspects of store development andoperations, including physical space, staffing, and managing all technology infrastructure that helps consumer brands to grow and deepen their customer brand experience.The company was founded in 2018 and is headquartered in New York City. $11M / Series A / Aug 26, 2021
Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of clinical and molecular data, and an operating system to make that data accessible and useful, Tempus enables physicians to make real-time, data-driven decisions todeliver personalized patient care and in parallel facilitates discovery, development and delivery of optimal therapeutics. The goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as the company gathers more data. $200M / Series G / Dec 10, 2020
Blueprint is an AI-powered assistant for therapists. Blueprint automates progress notes, drafts smart treatment plans, and surfaces actionable insights before, during, and after every client session. The company's mission is to build AI-assisted products to enable therapist-powered care. $3.4M / Seed / Dec 09, 2020
Imagine a world where Fee-For-Service has been deprecated in favor of direct contracts between employers and providers. A world where physicians' main job is not to document encounters just to optimize for billing. In such a world, the Electronic Medical Record as we know it will cease to exist and fixed prices for global case rates willoptimize the system for outcomes as opposed to number of encounters. $2.5M / Series A / Nov 01, 2019
Nubundle provides access to a concierge network of experienced family planning and fertility experts, preferred pricing at clinics and pharmacies, and just in time financing - all as a pass through employee benefit. $1.5M / Seed / Nov 26, 2018
SpotHero is the leading & only independent consumer marketplace for parking in North America. $10.1M / Series C / Sep 06, 2018
Exicure is Formerly Known as AuraSense Therapeuticsis. Exicure is developing a new class of immunomodulatory and gene silencing drugs against validated targets. Our 3-dimensional, spherical nucleic acid (SNA™) architecture unlocks the potential of nucleic acid therapeutics in multiple organs. Our lead programs address diseases from inflammatorydisorders to oncology.SNA constructs overcome one of the most difficult obstacles to nucleic acid therapeutics: safe and effective delivery into cells and tissues. SNA constructs exhibit unparalleled transfection efficiency into numerous cell and tissue types including the skin without carriers or transfection agents. Moreover, SNAs can be used as potent immunotherapeutic agents for the treatment of cancer or infectious disease. $20M / Venture - Series Unknown / Sep 27, 2017
See all 88 investments →

Co-Investors

Lightbank

About Lightbank

VC Fund · Chicago, United States

Lightbank VC is a $700M AUM venture fund that invests in early-stage vertically focused AI, consumer, enterprise, healthcare, crypto, fintech and climate companies. It focuses on pre-seed, seed and Series A opportunities where they write initial checks between $250k - $5m. They have invested in over 150 companies such as Tempus, Udemy, Fiverr(NYSE: FVRR), Sprout Social (NYSE: SPRT), Boom Supersonic, Tastytrade (acq. $1B+), Extend, Attain, Paytient and Expel.

Lightbank Contacts

NameEmailPhoneSocials
Bill Pescatello
Bill Pescatello Advisor or General Partner
Bradley Keywell
Bradley Keywell Co-Founder & Managing Partner
Eric Lefkofsky
Eric Lefkofsky Co-founder & Managing Partner
Eric Ong
Eric Ong Partner

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FAQ

What does Eric Lefkofsky invest in?

Eric Lefkofsky invests primarily in E-Commerce, Mobile and Software startups, most often at Seed and Series A stage. Most of the 88 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Eric Lefkofsky?

Public channels for Eric Lefkofsky include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Eric Lefkofsky last invest?

The most recent investment recorded for Eric Lefkofsky closed in Apr 2025. Shizune tracks 88 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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