Dental Innovation Alliance
VC Fund
Raleigh, United States
Dental Innovation Alliance (DIA) is a venture capital company that invests in, advises on, and accelerates the growth of early-stage companies that are transforming dentistry through technology.
- Total investments:
- 11
- Last investment:
- Lead investor:
- 73%
Last updated:
For AI agents: llms.txt
Industries Dental Innovation Alliance invests in
Stages Dental Innovation Alliance invests in
Countries Dental Innovation Alliance invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Round size
- Seed
- $1.8M–$2.1M
- Series A
- $4.5M–$5.5M
Investment Focus
Industry
- Dental 5 (45%)
- Health Care 5 (45%)
- Software 3 (27%)
- Medical 2 (18%)
- Wellness 2 (18%)
Stage
- Seed 2 (18%)
- Series A 2 (18%)
- Funding Round 2 (18%)
- Venture - Series Unknown 2 (18%)
- Series B 1 (9%)
Country
- United States 5 (45%)
- Belgium 1 (9%)
- Germany 1 (9%)
- Switzerland 1 (9%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Mark Friedman
EVP, Operations and Investments
|
EVP, Operations and Investments | Total investments: 0 | Find email |
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Relu is a young and driven company that works closely with dental and maxillofacial experts to develop advanced imaging software. It developed a web application that automatically segments 3D medical images using artificial intelligence called the "Virtual Patient Creator." | $1.8M / Seed / Aug 04, 2026 | ||
| Alta Smiles provides patent-pending orthodontic clinical support solutions. It is driven by a mission to make orthodontic and oral care solutions more accessible and convenient through innovation and technology. | Seed / Jul 23, 2026 | ||
| Pearl is the global leader in dental AI, reshaping oral healthcare with tools that raise the standard for diagnostic accuracy, trust, and innovation. Founded in 2019, Pearl helps clinicians, practice owners, universities and public health systems deliver consistent, high-quality care and stronger practice performance.With the broadest AIfootprint in dentistry, Pearl powers everything from chairside diagnosis to enterprise intelligence—elevating care and driving growth across diverse clinical environments. Our solutions are built in close partnership with those who use them—providers, practice managers, and educators at leading dental colleges worldwide. That’s why Pearl’s products reflect real-world workflows and integrate with the widest array of imaging and practice management systems, enabling teams to streamline operations and enhance care.Pearl’s diagnostic AI assistant, Second Opinion®, is FDA-cleared to detect disease in dental x-rays for patients 4+ and holds more regulatory clearances—including in over 120 countries—than any other solution. Pearl’s Practice Intelligence® and Precheck® further boost efficiency by surfacing revenue opportunities, automating insurance verification, and giving practices the data they need to grow with confidence. This year, Second Opinion 3D® became the first FDA-cleared AI capable of identifying disease in CBCT scans.As dentistry’s AI leader, Pearl is committed to advancing robust, accessible tools that elevate care for billions worldwide by improving health outcomes and building greater trust in dental medicine. | Venture - Series Unknown / May 07, 2024 | ||
| Lumendo is a medtech startup that develops light-active medical fillers for elegant and time saving surgeries. The fillers allow time-saving surgery for the best patient outcome. These can be used to form implants in any cavity inside the body. Lumendo was founded on 2018 and is headquartered in Renens, Switzerland. | $5.5M / Series A / Mar 13, 2024 | ||
| Lumendo is a medtech startup that develops light-active medical fillers for elegant and time saving surgeries. The fillers allow time-saving surgery for the best patient outcome. These can be used to form implants in any cavity inside the body. Lumendo was founded on 2018 and is headquartered in Renens, Switzerland. | Venture - Series Unknown / Jan 15, 2024 | ||
| Cloud Dentistry is an online interactive platform for dental offices to connect with dental staff in real-time. The platform's messenger allows users to communicate directly. The company was founded in 2014 and is based in Houston, Texas, United States. | Series B / Oct 25, 2023 | ||
| Dentognostics is a reasearch based firm that offers medicine and dentistry innovative and powerful systems for diagnostics, and therapy. | Aug 09, 2023 | ||
| Relu is a young and driven company that works closely with dental and maxillofacial experts to develop advanced imaging software. It developed a web application that automatically segments 3D medical images using artificial intelligence called the "Virtual Patient Creator." | $2.1M / Seed / Mar 09, 2023 | ||
| UptimeHealth, headquartered in Boston, MA, is a software startup that simplifies medical device service events, purchases, and compliance practices through automation and predictive analytics.The company focuses on providing administrators and operators with simple-to-use software to manage compliance tasks, gain access to actionable data toincrease operational efficiencies, and tap into the largest network of qualified biomed technicians to support their medical devices. | $4.5M / Series A / Jan 26, 2023 | ||
| Developer of an image-guided robotic restorative dentistry platform for crowns and fillings. CYBERDONTICS enables dentists to identify, remove and restore tooth decay with higher precision than is currently possible using human senses and human hands. CYBERDONTICS adds capacity to dental clinics. For patients, CYBERDONTICS aims to provide superiorrestorations at a lower cost and in less time. | |||
| See all 11 investments → | |||
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FAQ
What does Dental Innovation Alliance invest in?
Dental Innovation Alliance invests primarily in Dental, Health Care and Software startups, most often at Seed and Series A stage. Most of the 11 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What round sizes does Dental Innovation Alliance invest in?
Dental Innovation Alliance typically joins rounds of $1.8M–$2.1M at Seed and $4.5M–$5.5M at Series A. These are whole funding-round sizes, not Dental Innovation Alliance's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Dental Innovation Alliance took part in.
How do I contact Dental Innovation Alliance?
Public channels for Dental Innovation Alliance include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Dental Innovation Alliance?
The team at Dental Innovation Alliance includes Mark Friedman (EVP, Operations and Investments). The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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