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Sean O'Sullivan, Managing General Partner and Founder at SOSV

Sean O'Sullivan

Managing General Partner and Founder @ SOSV

Princeton, United States

Sean O'Sullivan is a convertible note investor at SOSV in Princeton focused on Biotechnology and Health Care. Sean O’Sullivan is the Founder and Managing General Partner of SOSV. He previously worked at Mapflow as a Chairman. Sean O’Sullivan attended Rensselaer Polytechnic Institute.

Total investments:
74
Last investment:
Lead investor:
16%

Last updated:

Industries Sean O'Sullivan invests in

BiotechnologyHealth CareHealth DiagnosticsCar SharingTransportation

Stages Sean O'Sullivan invests in

Convertible NoteSeedPre-SeedFunding RoundSeries A

Countries Sean O'Sullivan invests in

United StatesIrelandIndiaSpainFrance

Round sizes

Seed $31k–$3.3MPre-Seed $250k–$1.5M

Round size

Seed
$31k–$3.3M
Pre-Seed
$250k–$1.5M

Investment Focus

Industry

  • Biotechnology 13 (18%)
  • Health Care 7 (9%)
  • Health Diagnostics 4 (5%)
  • Car Sharing 3 (4%)
  • Transportation 3 (4%)
See all 62 industries →

Stage

  • Convertible Note 10 (14%)
  • Seed 9 (12%)
  • Pre-Seed 3 (4%)
  • Funding Round 3 (4%)
  • Series A 2 (3%)
See all 10 stages →

Country

  • United States 18 (24%)
  • Ireland 2 (3%)
  • India 1 (1%)
  • Spain 1 (1%)
  • France 1 (1%)
See all 10 countries →

Investments

CompanyDescriptionRoundLinks
VALANX Biotech VALANX Biotech
VALANX Biotech is a site-specific protein conjugation platform to enable fast and cost efficient protein-drug-conjugates development. $3.5M / Venture - Series Unknown / Mar 12, 2026
Prellis Biologics Prellis Biologics
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics'​ technology leverages massive gains in print speed and resolution to break the microvasculature barrier.The companywas founded in 2016 and is based in San Francisco, California. Series C / Nov 07, 2025
Flore by Sun Genomics Flore by Sun Genomics
Sun Genomics is a precision nutrition company focused on curing dysbiosis through the gut microflora and personalized solutions. Its flagship product Floré, is a microbiome test and custom synbiotics solution that utilizes whole-genome sequencing to evaluate different digestive system data points and ensure that customers receive a completelypersonalized product based on their unique gut profiles. The company also offers: Floré Tots, Kids, and Baby, available for kids up to age 0-12, and comes in an easy digestive powder to mix with their favorite drink. Floré Clinical, which is specifically for professional practitioners and their patients. Floré Defense, Balance, and Performance for sports teams and athletes. Convertible Note / Aug 15, 2025
Prellis Biologics Prellis Biologics
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics'​ technology leverages massive gains in print speed and resolution to break the microvasculature barrier.The companywas founded in 2016 and is based in San Francisco, California. Series C / Mar 10, 2025
Flore by Sun Genomics Flore by Sun Genomics
Sun Genomics is a precision nutrition company focused on curing dysbiosis through the gut microflora and personalized solutions. Its flagship product Floré, is a microbiome test and custom synbiotics solution that utilizes whole-genome sequencing to evaluate different digestive system data points and ensure that customers receive a completelypersonalized product based on their unique gut profiles. The company also offers: Floré Tots, Kids, and Baby, available for kids up to age 0-12, and comes in an easy digestive powder to mix with their favorite drink. Floré Clinical, which is specifically for professional practitioners and their patients. Floré Defense, Balance, and Performance for sports teams and athletes. Convertible Note / Nov 19, 2024
MixRift MixRift
MixRift is a gaming company that specializes in designing and developing interactive and mixed-reality gaming experiences. $1.5M / Pre-Seed / Aug 07, 2024
VALANX Biotech VALANX Biotech
VALANX Biotech is a site-specific protein conjugation platform to enable fast and cost efficient protein-drug-conjugates development. Seed / Jul 16, 2024
GlowDx GlowDx
GlowDx is decentralising molecular testing through point-of-care testing using a novel molecular technology. This enables local access, reducing both the economic and disease burden of patients. Convertible Note / Jun 18, 2024
MixRift MixRift
MixRift is a gaming company that specializes in designing and developing interactive and mixed-reality gaming experiences. Pre-Seed / May 02, 2024
Cell BioEngines Cell BioEngines
Cell BioEngines, Inc., is a clinical-stage biotech company focused on curing cancer by developing ”off-the-shelf” allogenic cell therapies. The company leverages its proprietary Stem-SPACE platform technology to produce clinical grade cells at scale. $500K / Pre-Seed / Apr 23, 2024
See all 74 investments →

Co-Investors

SOSV

About SOSV

VC Fund · Princeton, United States

SOSV is a global venture capital firm that focuses on deep tech investments through the HAX and IndieBio startup development programs aimed at human and planetary health. The firm invests in startups at their inception, providing support to accelerate their next institutional funding round. HAX offers facilities and engineering resources, whileIndieBio provides services and lab equipment for founders. The firm targets deep technology innovations in the health and environmental sectors.

SOSV Contacts

NameEmailPhoneSocials
Arvind Gupta
Arvind Gupta General Partner
Blaine Doyle
Blaine Doyle Mentor
Cyril Ebersweiler
Cyril Ebersweiler General Partner
Deborah Zajac
Deborah Zajac General Partner
Duncan Turner
Duncan Turner General Partner

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FAQ

What does Sean O'Sullivan invest in?

Sean O'Sullivan invests primarily in Biotechnology, Health Care and Health Diagnostics startups, most often at Convertible Note and Seed stage. Most of the 74 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Sean O'Sullivan's check size?

Sean O'Sullivan typically joins rounds of $31k–$3.3M at Seed and $250k–$1.5M at Pre-Seed. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Sean O'Sullivan participates in.

When did Sean O'Sullivan last invest?

The most recent investment recorded for Sean O'Sullivan closed in Mar 2026. Shizune tracks 74 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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