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Rishi Gupta, Private Equity Partner at OrbiMed

Rishi Gupta

Private Equity Partner @ OrbiMed

Rishi Gupta is a Series A investor at OrbiMed focused on Biotechnology and Health Care. Rishi Gupta, J.D., is a Private Equity Partner. Previously, he was a healthcare investment banker at Raymond James & Associates, served as Manager of Corporate Development at Veritas Medicine, and was a summer associate at Wachtell, Lipton, Rosen & Katz. Mr. Gupta has published scientific articles on the mechanisms of HIV entry intohost cells and legal articles on intellectual property laws in the developing world. He received his A.B. degree magna cum laude in Biochemical Sciences from Harvard College and holds a J.D. from the Yale Law School.

Total investments:
12
Last investment:
Lead investor:
42%

Last updated:

Industries Rishi Gupta invests in

BiotechnologyHealth CareTherapeuticsMedicalRetail

Stages Rishi Gupta invests in

Series ASeries BSeedAngel

Countries Rishi Gupta invests in

United StatesIndiaUnited Kingdom

Contacts

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Investment Focus

Industry

  • Biotechnology 7 (58%)
  • Health Care 4 (33%)
  • Therapeutics 4 (33%)
  • Medical 2 (17%)
  • Retail 1 (8%)
See all 15 industries →

Stage

  • Series A 7 (58%)
  • Series B 3 (25%)
  • Seed 1 (8%)
  • Angel 1 (8%)

Country

  • United States 7 (58%)
  • India 1 (8%)
  • United Kingdom 1 (8%)

Investments

CompanyDescriptionRoundLinks
CHARM Therapeutics CHARM Therapeutics
CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins. $80M / Series B / Sep 02, 2025
Helicore Biopharma Helicore Biopharma
Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders. $65M / Series A / Jan 28, 2025
Aer Therapeutics Aer Therapeutics
Aer Therapeutics is a clinical-stage biopharmaceutical company that develops an approach to treat lung disease with excess mucus and mucus plugs. The company focuses on treating respiratory diseases with significant unmet needs, such as COPD, cystic fibrosis, and asthma. $36M / Series A / Apr 13, 2023
Delfi Diagnostics Delfi Diagnostics
Delfi Diagnostics detect cancer early, when it is most curable, using high precision non-invasive blood tests. It uses artificial intelligence and genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients. $225M / Series B / Jul 18, 2022
CHARM Therapeutics CHARM Therapeutics
CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins. $50M / Series A / Jun 09, 2022
Delfi Diagnostics Delfi Diagnostics
Delfi Diagnostics detect cancer early, when it is most curable, using high precision non-invasive blood tests. It uses artificial intelligence and genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients. $101.1M / Series A / Jan 12, 2021
Enliven Therapeutics Enliven Therapeutics
Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.The company's discovery process combines clinically validated biological targets and industry-leading chemistry to address the limitations of existing therapies. This approach allows us to efficiently and effectivelydevelop precision oncology therapeutics that enhance overall patient well-being.Founded in July 2019 by Sam Kintz, MBA, Joe Lyssikatos, PhD, and Anish Patel, PharmD, Enliven Therapeutics is based in Boulder, Colorado. $55M / Series A / Dec 07, 2020
Enliven Therapeutics Enliven Therapeutics
Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.The company's discovery process combines clinically validated biological targets and industry-leading chemistry to address the limitations of existing therapies. This approach allows us to efficiently and effectivelydevelop precision oncology therapeutics that enhance overall patient well-being.Founded in July 2019 by Sam Kintz, MBA, Joe Lyssikatos, PhD, and Anish Patel, PharmD, Enliven Therapeutics is based in Boulder, Colorado. Seed / Jan 01, 2019
Modis Therapeutics Modis Therapeutics
Modis Therapeutics is bringing disease-modifying therapies to patients with rare genetic diseases. $30M / Series A / Oct 01, 2018
Attenua Attenua
Attenua, Inc. is a virtual biotech company formed to develop therapies for debilitating conditions neglected by Big Pharma's shift to specialty Pharma and biologics. They believe small molecule Blockbuster drugs that would benefit millions are still to be discovered.They have assembled a team of leading scientists and ex-Big Pharma advisorswith many years of drug development expertise. Their team has previous work experience at Merck, GSK, AstraZeneca, and Genentech. $35M / Series A / May 01, 2018
See all 12 investments →

Co-Investors

OrbiMed

About OrbiMed

VC Fund · New York, United States

OrbiMed is a healthcare-dedicated investment firm, with approximately $5 billion in assets under management. OrbiMed's investment advisory business was founded in 1989 with a vision to invest across the spectrum of healthcare companies: from private start-ups to large multinational companies. OrbiMed manages the Caduceus Private Investmentsseries of venture capital funds and a family of public equity investment funds.

OrbiMed Contacts

NameEmailPhoneSocials
Dina Chaya
Dina Chaya Partner
Kevin Koch
Kevin Koch Venture Partner
Rishi Gupta
Rishi Gupta Private Equity Partner
Sunny Sharma
Sunny Sharma Senior Managing Director
Tadd S. Wessel
Tadd S. Wessel Managing Director

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FAQ

What does Rishi Gupta invest in?

Rishi Gupta invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 12 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Rishi Gupta?

Public channels for Rishi Gupta include LinkedIn. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Rishi Gupta last invest?

The most recent investment recorded for Rishi Gupta closed in Sep 2025. Shizune tracks 12 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Sep 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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