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Prefix Capital, VC Fund

Prefix Capital

VC Fund

San Francisco, United States

Prefix Capital is an early-stage, deep-tech VC that invests in foundational technologies. It was founded in 2019 and is based in San Francisco, California.

Total investments:
13
Last investment:
Lead investor:
31%

Last updated:

Industries Prefix Capital invests in

Information TechnologyArtificial IntelligenceMachine LearningSaaSVideo

Stages Prefix Capital invests in

SeedSeries ASeries BSeries CFunding Round

Countries Prefix Capital invests in

United StatesIreland

Contacts

NameEmailPhoneSocials
Byron Alsberg Byron Alsberg

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Investment Focus

Industry

  • Information Technology 4 (31%)
  • Artificial Intelligence 4 (31%)
  • Machine Learning 3 (23%)
  • SaaS 2 (15%)
  • Video 2 (15%)
See all 30 industries →

Stage

  • Seed 8 (62%)
  • Series A 2 (15%)
  • Series B 1 (8%)
  • Series C 1 (8%)
  • Funding Round 1 (8%)

Country

  • United States 9 (69%)
  • Ireland 1 (8%)

Team

NameTitleInvestmentsLinksEmail
Byron Alsberg
Byron Alsberg Founder and General Partner
Founder and General Partner Total investments: 4
Find email
Owen Van Natta
Owen Van Natta Founder and Managing Partner
Founder and Managing Partner Total investments: 36
Find email

Investments

CompanyDescriptionRoundLinks
Symmetry Systems Symmetry Systems
Symmetry Systems operates as a data and AI security company delivering a security-first platform called DataGuard, designed for visibility and governance of sensitive data across hybrid environments. It employs AI-driven scanning to discover, classify, and map structured and unstructured data across cloud and on-prem systems, then continuouslymonitors access patterns, detects anomalies, and enforces data governance policies without compromising custody of the data. The platform can be deployed in high-assurance and air-gapped environments, handles sensitive data even in restricted settings, and integrates with existing security stacks to support compliance and security teams in implementing data-centric zero-trust models. $17.7M / Series B / Aug 09, 2023
Base Operations Base Operations
Base Operations is the creator of a threat intelligence platform that aggregates, visualizes, and interprets threat data to assist organizations minimize risk and protect people and assets. The platform provides a granular threat database with AI-powered predictive analytics to quickly uncover actionable insights, improving response time andaccuracy for enterprise security tasks, and includes a dashboard for security personnel, allowing clients to connect with their employees in the field, manage their trips, and improve their safety. $3M / Seed / Dec 14, 2021
Vidrovr Vidrovr
Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York. $2.5M / Seed / Aug 18, 2021
Symmetry Systems Symmetry Systems
Symmetry Systems operates as a data and AI security company delivering a security-first platform called DataGuard, designed for visibility and governance of sensitive data across hybrid environments. It employs AI-driven scanning to discover, classify, and map structured and unstructured data across cloud and on-prem systems, then continuouslymonitors access patterns, detects anomalies, and enforces data governance policies without compromising custody of the data. The platform can be deployed in high-assurance and air-gapped environments, handles sensitive data even in restricted settings, and integrates with existing security stacks to support compliance and security teams in implementing data-centric zero-trust models. $15M / Series A / Jun 23, 2021
VIA VIA
VIA helps energy companies across the globe realize the value of their data through AI and blockchain. The company enables an encrypted analysis of confidential and classified data. It solves asset management and operational issues alongside key players in the energy industry and works with governments, regulators, and large global utilities on AIinitiatives like predictive maintenance and contingency planning.Founded in 2016, VIA is headquartered in Somerville, Massachusetts. $10.1M / Series A / May 11, 2021
VidMob VidMob
VidMob is the world's leading platform for Intelligent Creative. We provide an end-to-end technology solution for all of a brand’s creative needs. It is an integrated platform combining AI-powered creative analytics with a production workflow system connected to a global network of expert creators. VidMob’s platform dramatically improves adcampaign ROI through actionable creative insights, faster creative turnaround, better performing ads and streamlined workflow. We are the only company in the world to receive a certified creative marketing partner badge from every major social and digital platform. A portion of every dollar VidMob receives is used to fund pro bono creative services for non-profits through the 501(c)(3) VidMob Gives. $50M / Series C / Feb 23, 2021
Aligned Carbon Aligned Carbon
Aligned Carbon is a supplier of aligned carbon nanotubes, enabling 1000x improvement in computing. It has provided its product of wafer-scale aligned carbon nanotube arrays to more than a dozen university research groups and industrial research labs.Aligned Carbon was formed in early 2018 by three friends and labmates from Stanford University.Collectively Aligned Carbon’s team represents over 35 years of nanotechnology experience with 100+ peer-reviewed publications and inventorship for 15+ patents. $1M / Seed / Sep 18, 2020
Symmetry Systems Symmetry Systems
Symmetry Systems operates as a data and AI security company delivering a security-first platform called DataGuard, designed for visibility and governance of sensitive data across hybrid environments. It employs AI-driven scanning to discover, classify, and map structured and unstructured data across cloud and on-prem systems, then continuouslymonitors access patterns, detects anomalies, and enforces data governance policies without compromising custody of the data. The platform can be deployed in high-assurance and air-gapped environments, handles sensitive data even in restricted settings, and integrates with existing security stacks to support compliance and security teams in implementing data-centric zero-trust models. $3M / Seed / Aug 11, 2020
Neocortix Cloud Services Neocortix Cloud Services
Neocortix Cloud Services provides Distributed Cloud Computing services running on public Android phones. It enables the Last-Mile Load Test, CDN Test, and Network Telemetry at a lower cost and greater accuracy than is possible with conventional data centers. It aims to organize the world's computation and make it universally accessible anduseful. It was founded in 2013 and is located in Santa Clara, California. Seed / Aug 05, 2020
Neutrolis Neutrolis
Neutrolis is a candidate-stage company advancing its first-in-class therapies that target Neutrophil Extracellular Traps (NETs). NETs are a fundamental arm of the immune system and play an important role in chronic and acute diseases. Although NETs represent one of the most important immunology discoveries in the past 20 years, there is no therapyon the market that effectively targets and removes NETs. Neutrolis was founded by two of the earliest and most cited leaders in the NETs field and supported by a seasoned biotech executive with a track record of successful M&A. The company’s pipeline includes NTR-441 and NTR-10, that effectively removes NETs and halt their pathologic effects on end-organs. Neutrolis has a strong patent portfolio for new molecular entity and method of use. The lead molecule, NTR-441, is slated to enter clinical trials in 2021. Oct 01, 2019
See all 13 investments →

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FAQ

What does Prefix Capital invest in?

Prefix Capital invests primarily in Information Technology, Artificial Intelligence and Machine Learning startups, most often at Seed and Series A stage. Most of the 13 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Prefix Capital?

Public channels for Prefix Capital include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Prefix Capital?

The team at Prefix Capital includes Byron Alsberg (Founder and General Partner) and Owen Van Natta (Founder and Managing Partner). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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