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Nathanael Lentz, Managing Partner at Osage Venture Partners

Nathanael Lentz

Managing Partner @ Osage Venture Partners

Bala Cynwyd, United States

Nathanael Lentz is a Series A investor at Osage Venture Partners in Bala Cynwyd focused on Software and Enterprise Software. Nathanael V. Lentz is based out of Philadelphia, Pennsylvania and is the Managing Partner of Osage Venture Partners. Nathanael previously worked at DeepSurface Security as a Board Observer. Nathanael V. Lentz attended the Stanford University Graduate School of Business.

Total investments:
56
Last investment:
Lead investor:
29%

Last updated:

Industries Nathanael Lentz invests in

SoftwareEnterprise SoftwareArtificial IntelligenceMachine LearningInformation Technology

Stages Nathanael Lentz invests in

Series ASeedSeries BVenture - Series UnknownSeries C

Countries Nathanael Lentz invests in

United StatesIsrael

Contacts

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Investment Focus

Industry

  • Software 17 (30%)
  • Enterprise Software 10 (18%)
  • Artificial Intelligence 10 (18%)
  • Machine Learning 7 (13%)
  • Information Technology 7 (13%)
See all 67 industries →

Stage

  • Series A 16 (29%)
  • Seed 9 (16%)
  • Series B 9 (16%)
  • Venture - Series Unknown 4 (7%)
  • Series C 3 (5%)
See all 8 stages →

Country

  • United States 30 (54%)
  • Israel 1 (2%)

Investments

CompanyDescriptionRoundLinks
Iridius is the compliance-by-design AI platform that enables regulated enterprises to design, build, and operate AI systems that are continuously compliant. In regulated industries, AI isn’t failing because of model capability — it’s failing because it can’t operate within real-world constraints: fragmented systems, complex workflows, and strictregulatory compliance requirements. Instead of treating compliance as a manual process that happens after systems are built, Iridius makes compliance part of how systems run. $8.6M / Seed / Apr 23, 2026
Dig Dig
GlossAI bridges the gap between the content created by organisations and how people consume it .Today's audiences do not have the attention span to listen to anything for an extended period of time. Even those attending events, podcasts, training sessions, and zoom calls can't keep up. At GlossAI we get smart AI video generator that canturn any single piece of content into many short videos, blog posts and more various channels and use cases. $14M / Series A / Feb 23, 2025
Clinical Maestro™ by Strategikon Pharma is the only commercially available software platform for the end- to- end management of “clinical business operations”, which is the pharmaceutical industry vertical for planning, outsourcing and budgeting clinical trials. Biopharmaceutical companies outsource 90% of their clinical development pipelinespending billions of dollars engaging in highly complex outsourced relationships with thousands of global service providers, each using their own processes, systems and reporting structures. These sophisticated relationships require complex outsourcing strategies, demanding clinical financial planning, extensive sourcing due diligence and rigorous performance management. Currently the industry manages these activities in Excel, using labor intensive, inefficient processes, costing billions of dollars in infrastructure costs, regulatory non-compliance fines and delays to market. Clinical Maestro takes a radically different approach to the management of clinical portfolio through a transformative redesign of Excel-driven processes into end-to-end integrated workflows, breaking the communication and data integration siloes between pharma companies and their outsourcing partners. Clinical Maestro™ cases studies with leading pharmaceutical companies and CROs demonstrate savings of >80% vs. manual processes, >95% prediction accuracy for clinical study budgets and high user satisfaction and engagement. $7M / Series A / Feb 06, 2024
Arcanna.ai develops an AI-powered cybersecurity platform with the goal of increasing security operations efficiency by augmenting and scaling SOC analyst capacity. Arcanna.ai enables experts to train context-aware AI models that incorporate their cybersecurity and organizational distinctiveness knowledge and experience. For addressing today'sand tomorrow's attack volumes, Arcanna.ai employs an innovative and proprietary method for expert knowledge integration into a neural net that combines a continuous human feedback-loop, natural language processing, and deep learning. $3.5M / Seed / Dec 19, 2023
DeepHow develops an AI-powered learning platform for manufacturing, service, and repair. Wei-Liang Kao, Patrik Matos da Silva, and Samuel Zheng founded it in 2018, with its headquarters in New York City. $14M / Series A / Dec 28, 2022
Curavit is a “virtual CRO”, purpose-built to design and execute decentralized clinical trials. The company works with our clients to design their trials from first principles, based on the team’s decades of experience in research and digital health technologies. For each trial, they assign an experienced principal investigator, who is an expert inthe specific disease area, to develop the protocol and drive the regulatory submission process. Curavit manages participant recruitment, enrollment, and consent. Under the direction of the PI, their clinical study team executes the entire decentralized clinical trial. $5M / Series A / Nov 14, 2022
DeepSurface Security (www.deepsurface.com) is the first automated Predictive Vulnerability Management suite of tools that helps cybersecurity teams automate the process of analyzing and prioritizing vulnerabilities by risk contribution on enterprise networks. Created by a veteran cybersecurity team, DeepSurface Security is trusted by enterprisecompanies to identify, prioritize, and research vulnerabilities in their networks. Headquartered in Portland, Oregon, DeepSurface is a privately held company funded by Cascade Seed Fund, SeaChange Fund, and Voyager Capital. To learn more visit www.deepsurface.com. $4.5M / Seed / Feb 08, 2022
Malbek is an AI-fueled platform that provides enterprise contract lifecycle management that help organizations streamline contracting processes including request, redline review, approvals, signature, renewals, and and obligation tracking. The most modern and cutting-edge contract lifecycle management solution that is laser-focused on acceleratingcontract cycle time, improving efficiency, and increasing contract visibility. With a consumer-grade simplified user experience, it is a no-code and highly configurable solution for small, medium and large global businesses. $15.3M / Series A / Sep 28, 2021
DeepHow develops an AI-powered learning platform for manufacturing, service, and repair. Wei-Liang Kao, Patrik Matos da Silva, and Samuel Zheng founded it in 2018, with its headquarters in New York City. $9M / Seed / Sep 15, 2021
Mona provides intelligent and flexible AI monitoring for AI-first companies and teams who need to continuously adapt and optimize their production environments for fast business growth. Our platform enables machine learning teams to track data and model performance metrics in production, and get alerted on potential drifts. biases and integrityissues, to business risk and enable fast and reliable improvements. Customers across verticals use the platform for a variety of use cases such as fraud detection, data-driven healthcare, e-commerce marketing optimization, and revenue intelligence. Founded in late 2018 by product leaders and operators from Google and McKinsey & Co. $7M / Seed / Aug 01, 2021
See all 56 investments →

Co-Investors

Osage Venture Partners

About Osage Venture Partners

VC Fund · Bala Cynwyd, United States

Osage Venture Partners (OVP) invests in early stage, business-to-business (B2B) software companies headquartered on the East Coast from its offices just outside of Philadelphia, PA. With over $175M under management, OVP seeks to invest in determined and creative entrepreneurs and provide them with the assistance required to build high growthbusinesses.

Osage Venture Partners Contacts

NameEmailPhoneSocials
Claudia Dunnous
Claudia Dunnous Chief Financial Officer
Emily Foote
Emily Foote Principal
James Quigley
James Quigley Entrepreneur In Residence
Jon Gulardo
Jon Gulardo Associate
Nathanael Lentz
Nathanael Lentz Managing Partner

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FAQ

What does Nathanael Lentz invest in?

Nathanael Lentz invests primarily in Software, Enterprise Software and Artificial Intelligence startups, most often at Series A and Seed stage. Most of the 56 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Nathanael Lentz?

Public channels for Nathanael Lentz include LinkedIn, X (Twitter) and Facebook. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Nathanael Lentz last invest?

The most recent investment recorded for Nathanael Lentz closed in Apr 2026. Shizune tracks 56 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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