Main Sequence Ventures
VC Fund
Sydney, Australia
Main Sequence Ventures is a VC fund in Sydney focused on Artificial Intelligence and Software. Main Sequence Ventures invests in ambitious founders creating the next set of global industries leveraging deep tech or frontier technologies. The firm is backed by the Australian National Science Agency, CSIRO, the Australian Federal Government, and private investors. All Main Sequence investments leverage world-leading research from Australian public research organizations such as CSIRO, any of Australia's 41 universities or its multitude of other industry research agencies.
- Total investments:
- 137
- Last investment:
- Lead investor:
- 42%
- Fund size:
- $305M
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Main Sequence Ventures invests in
Stages Main Sequence Ventures invests in
Countries Main Sequence Ventures invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 7 contacts → | |||
Round size
- Seed
- $1M–$7M
- Series A
- $4.8M–$30M
- Series B
- $14M–$72M
Investment Focus
Industry
- Artificial Intelligence 14 (10%)
- Software 13 (9%)
- Information Technology 11 (8%)
- Manufacturing 8 (6%)
- Biotechnology 7 (5%)
Stage
- Seed 35 (26%)
- Series A 31 (23%)
- Series B 17 (12%)
- Venture - Series Unknown 10 (7%)
- Funding Round 7 (5%)
Country
- Australia 58 (42%)
- United States 5 (4%)
- Philippines 3 (2%)
- United Kingdom 1 (1%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Michael Zimmerman
Partner
|
Partner | Total investments: 18 | Find email | |
Phil Morle
Partner
|
Partner | Total investments: 21 | Find email | |
Alezeia Brown
Investment Manager
|
Investment Manager | Total investments: 5 | Find email | |
Bill Bartee
Partner
|
Partner | Total investments: 28 | Find email | |
Jun Qu
Deep tech VC
|
Deep tech VC | Total investments: 2 | Find email | |
| See all 7 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Universal Quantum is building quantum computers to tackle real-world problems that would take today’s fastest supercomputers billions of years to solve. | $100M / Series A / Oct 08, 2026 | ||
| Kinoxis Therapeutics is an early stage biotechnology company based in Australia that is working to progress the development of a range of novel therapeutic compounds for the treatment of substance use disorders and other CNS conditions. The company has licensed these compounds from the University of Sydney, with the lead candidate demonstratingpotent anti-addictive and prosocial effects in a number of different animal models and is progressing through pre-clinical testing. | $4.8M / Venture - Series Unknown / Sep 22, 2026 | ||
| Metacognition is an artificial intelligence company dedicated to building the next generation of intelligent AI agents and robotic software platforms. The company's core mission is to solve the problem of persistent memory and lifelong reasoning in always-on, multi-agent systems. | $7.2M / Pre-Seed / Sep 09, 2026 | ||
| Facet Amtech develops and produces ammonia from water and air. | $2.2M / Seed / Aug 26, 2026 | ||
| Zabidou develops laser-based sensing systems that give machines real-time perception to separate materials and improve sorting efficiency. | $2.5M / Seed / Aug 04, 2026 | ||
| Emesent is a venture-backed technology company that automates the collection and analysis of critical data in challenging underground environments. Our flagship product is the award-winning Hovermap; a LiDAR-mapping and autonomy payload for industrial drones. Hovermap allows drones to fly and map in GPS-denied environments such as undergroundmines.Through Hovermap and other solutions, we deliver revolutionary efficiency, safety and operational insights to underground mines and other GPS-denied environments. Our growing team of experienced roboticists and engineers are dedicated to creating cutting-edge drone autonomy and data analytics for industrial applications. | $10.4M / Convertible Note / Jul 02, 2026 | ||
| Arkeus specializes in the quick design, creation, and production of autonomous optical capabilities for Search, Intelligence, Surveillance, and Reconnaissance (SISR). | $17.9M / Series A / May 15, 2026 | ||
| Semiconductor chip-based quantum magnetic field sensors using diamond - navigation, mining, medical imaging | $3.5M / Seed / Apr 14, 2026 | ||
| Cauldron Ferm is a bio-acceleration process that exponentially scales up any precision fermented prototype to commercial quantities faster and with a lower cost of goods than any traditional production method. | $13.3M / Series A / Mar 24, 2026 | ||
| Arlula provides the infrastructure and single access point that allows users to procure, manage and process satellite imagery at scale. Founded in 2018, Arlula aims to connect the value of Earth observation data from orbit to people and businesses on the ground. Our automation technology, ML tasking scheduler, and partnerships with global satelliteoperators, Government and research institutions, and technology companies to create the infrastructure that fuels the growth of the EO industry. Arlula is changing this by providing the infrastructure which will enable anyone to monitor our planet from space. | $2.4M / Seed / Mar 24, 2026 | ||
| See all 137 investments → | |||
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FAQ
What does Main Sequence Ventures invest in?
Main Sequence Ventures invests primarily in Artificial Intelligence, Software and Information Technology startups, most often at Seed and Series A stage. Most of the 137 investments tracked by Shizune back companies in Australia. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Main Sequence Ventures's check size?
Main Sequence Ventures typically joins rounds of $1M–$7M at Seed, $4.8M–$30M at Series A and $14M–$72M at Series B. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Main Sequence Ventures participates in.
How do I contact Main Sequence Ventures?
Public channels for Main Sequence Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Main Sequence Ventures?
The team at Main Sequence Ventures includes Michael Zimmerman (Partner), Phil Morle (Partner) and Alezeia Brown (Investment Manager), among 7 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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