Main Sequence Ventures
VC Fund
Sydney, Australia
Main Sequence Ventures is a VC fund in Sydney focused on Software and Artificial Intelligence. Main Sequence Ventures invests in ambitious founders creating the next set of global industries leveraging deep tech or frontier technologies. The firm is backed by the Australian National Science Agency, CSIRO, the Australian Federal Government, and private investors. All Main Sequence investments leverage world-leading research from Australianpublic research organizations such as CSIRO, any of Australia's 41 universities or its multitude of other industry research agencies.
- Total investments:
- 130
- Last investment:
- Lead investor:
- 40%
- Fund size:
- $303M
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Main Sequence Ventures invests in
Stages Main Sequence Ventures invests in
Countries Main Sequence Ventures invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Round size
- Seed
- $1M–$7M
- Series A
- $4.5M–$30M
- Series B
- $13M–$72M
Investment Focus
Industry
- Software 13 (10%)
- Artificial Intelligence 10 (8%)
- Manufacturing 7 (5%)
- Information Technology 7 (5%)
- Biotechnology 6 (5%)
Stage
- Seed 32 (25%)
- Series A 27 (21%)
- Series B 17 (13%)
- Funding Round 14 (11%)
- Pre-Seed 4 (3%)
Country
- Australia 53 (41%)
- United States 4 (3%)
- Philippines 3 (2%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Mike Zimmerman
Partner
|
Partner | Total investments: 18 | Find email | |
Phil Morle
Partner
|
Partner | Total investments: 20 | Find email | |
Alezeia Brown
Investment Manager
|
Investment Manager | Total investments: 5 | Find email | |
Bill Bartee
Partner
|
Partner | Total investments: 27 | Find email | |
Jun Qu
Deep tech VC
|
Deep tech VC | Total investments: 2 | Find email | |
| See all 7 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Zabidou
|
Zabidou develops laser-based sensing systems that give machines real-time perception to separate materials and improve sorting efficiency. | $2.5M / Seed / Aug 04, 2026 | |
Emesent
|
Emesent is a venture-backed technology company that automates the collection and analysis of critical data in challenging underground environments. Our flagship product is the award-winning Hovermap; a LiDAR-mapping and autonomy payload for industrial drones. Hovermap allows drones to fly and map in GPS-denied environments such as undergroundmines.Through Hovermap and other solutions, we deliver revolutionary efficiency, safety and operational insights to underground mines and other GPS-denied environments. Our growing team of experienced roboticists and engineers are dedicated to creating cutting-edge drone autonomy and data analytics for industrial applications. | $10.4M / Convertible Note / Jul 02, 2026 | |
Arkeus
|
Arkeus specializes in the quick design, creation, and production of autonomous optical capabilities for Search, Intelligence, Surveillance, and Reconnaissance (SISR). | $17.9M / Series A / May 15, 2026 | |
DeteQt
|
Semiconductor chip-based quantum magnetic field sensors using diamond - navigation, mining, medical imaging | $3.5M / Seed / Apr 14, 2026 | |
Cauldron Ferm
|
Cauldron Ferm is a bio-acceleration process that exponentially scales up any precision fermented prototype to commercial quantities faster and with a lower cost of goods than any traditional production method. | $13.3M / Series A / Mar 24, 2026 | |
|
Arlula
|
Arlula provides a single integration point for a global network of satellite imagery. | $2.4M / Seed / Mar 24, 2026 | |
Advanced Navigation
|
Advanced Navigation is a privately owned Australian company that specializes in the development of navigation technologies and robotics. The company has a focus on generating products of the highest quality standard, both in terms of hardware and software. The company's founders came from a background in mission critical robotics built tomilitary specifications and this can be seen through Advanced Navigation's products. Advanced Navigation's engineers have specialized expertise across a broad range of fields including sensors, GNSS, inertial navigation, RF technologies, acoustics, robotics, AI, and algorithms. | $111.9M / Series C / Mar 17, 2026 | |
MGA Thermal
|
MGA Thermal they are developing novel materials, designing innovative technologies, and delivering thermal energy storage solutions. They are improving the electrical grid’s stability, residential and commercial space heating, industrial process and waste heat, and even electric vehicles. Their focus, is enabling intermittent renewable energysources such as the sun and wind, to provide base load electricity to the grid. | $12M / Venture - Series Unknown / Mar 13, 2026 | |
Breaker
|
Breaker develops cutting-edge software that transforms the interaction between humans and machines. Our platform leverages advanced decision-making, natural language communication, and enhanced perception to enable sophisticated autonomous capabilities in machines previously only achievable with human oversight. Designed for diverse industries,Breakers’ software facilitates a new level of efficiency and versatility in uncrewed systems, promising to revolutionize the way autonomous assets operate and collaborate with humans. Our mission is to make intelligent, autonomous collaboration a reality, bridging the gap between human intuition and machine precision. | $6.4M / Seed / Feb 17, 2026 | |
Kasada
|
Kasada protects online, mobile, and API channels from system takeover, content scraping, DOS, and account takeover. Kasada challenges the economics of leveraging automation when abusing applications and APIs. | $20M / Dec 10, 2025 | |
| See all 130 investments → | |||
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FAQ
What does Main Sequence Ventures invest in?
Main Sequence Ventures invests primarily in Software, Artificial Intelligence and Manufacturing startups, most often at Seed and Series A stage. Most of the 130 investments tracked by Shizune back companies in Australia. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Main Sequence Ventures's check size?
Main Sequence Ventures typically joins rounds of $1M–$7M at Seed, $4.5M–$30M at Series A and $13M–$72M at Series B. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Main Sequence Ventures participates in.
How do I contact Main Sequence Ventures?
Public channels for Main Sequence Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Main Sequence Ventures?
The team at Main Sequence Ventures includes Mike Zimmerman (Partner), Phil Morle (Partner) and Alezeia Brown (Investment Manager), among 7 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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