Lionheart Ventures
VC Fund
San Francisco, United States
Lionheart Ventures is a global, seed-stage venture capital firm focused on mitigating civilizational risk. We do this by supporting the wise development of transformative technologies. Our main areas of investment focus are transformative artificial intelligence and frontier mental health technologies.Leading academics estimate a 1-in-6 chance ofhuman extinction by the year 2100, largely driven by risks from emerging technologies. And now, with the exponential growth of AI, predictions are getting worse. Our startups are part of the solution. We invest in exceptional, ethical founders who are developing transformative technologies that have the potential to impact humanity on a meaningful scale, while generating attractive returns for our LPs.
- Total investments:
- 42
- Last investment:
- Lead investor:
- 5%
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Lionheart Ventures invests in
Stages Lionheart Ventures invests in
Countries Lionheart Ventures invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 9 contacts → | |||
Round size
- Seed
- $2.3M–$11M
- Series A
- $25k–$50M
Investment Focus
Industry
- Health Care 13 (31%)
- Biotechnology 7 (17%)
- Wellness 6 (14%)
- Artificial Intelligence 6 (14%)
- Mental Health 5 (12%)
Stage
- Seed 27 (64%)
- Series A 9 (21%)
- Pre-Seed 1 (2%)
- Funding Round 1 (2%)
- Venture - Series Unknown 1 (2%)
Country
- United States 25 (60%)
- United Kingdom 5 (12%)
- Germany 2 (5%)
- Singapore 2 (5%)
- Canada 1 (2%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Shelby Clark
Partner, Mental Health
|
Partner, Mental Health | Total investments: 1 | Find email | |
Annie Caton-Wong
Executive Assistant
|
Executive Assistant | Total investments: 0 | Find email | |
Brandon Goldman
Partner
|
Partner | Total investments: 2 | Find email | |
Carlos López Enríquez
VP of Finance
|
VP of Finance | Total investments: 0 | Find email | |
David Langer
Founding Partner
|
Founding Partner | Total investments: 17 | Find email | |
| See all 9 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Piramidal offers artificial intelligence software that transforms brain activity into easy-to-understand health data to help diagnose neurological diseases. | $6M / Seed / Aug 21, 2024 | ||
| Xylo Bio is a drug development company that focuses on next-generation psychedelics. With psychedelic molecules as the starting point, our goal is to develop medicines that are widely available as improved treatments to currently available SSRI medications. | $3.2M / Seed / Oct 27, 2022 | ||
| Clerkenwell Health is an innovative mental health company offering clinical research support services and psychedelic-assisted therapies. By providing independent psychedelic-specialist CRO services, Clerkenwell will accelerate the adoption of these treatments across Europe. The team are passionate about putting patients at the centre ofclinical trial design and delivering gold standard therapy protocols. | $2.3M / Seed / Oct 10, 2022 | ||
| Corporate mental health and emotional wellness platform for Latin America | Seed / Sep 21, 2022 | ||
| Trek Health builds foundational software that empowers mental health providers to start working with insurance networks. The company's contact modes are by mail, phone, and physical address. | $2.7M / Seed / Sep 07, 2022 | ||
| Cognigenics transforms mental health in the genetic age through cognitive neuroengineering. The company’s business is cognitive neuroengineering, which is the genetic engineering of desirable cognitive traits, such as mindfulness, relaxation, and mental acuity. These cognitive assets can enhance human performance in normal individuals or offsetcognitive deficits in people suffering from mental health issues such as stress, anxiety, and depression (which are the initial applications). | $1.6M / Seed / Aug 16, 2022 | ||
| Carbon Crusher offers carbon crushing as a service to the public or private road owners or contractors. It helps its clients identify problem areas and giving them long-term road security with end-to-end service and support along the way. | Seed / Jun 09, 2022 | ||
| Homecoming is a provider of patient engagement tools for psychedelic therapy. | $4M / Seed / Apr 07, 2022 | ||
| WellSet is the first platform to find, book and recommend wellness practitioners. | Seed / Apr 07, 2022 | ||
| The Breathwrk app offers easy to follow and highly effective guided breathing exercises that alleviate anxiety, promote sleep, increase energy, improve mood, help with athletic performance, and more! | Seed / Apr 01, 2022 | ||
| See all 42 investments → | |||
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FAQ
What does Lionheart Ventures invest in?
Lionheart Ventures invests primarily in Health Care, Biotechnology and Wellness startups, most often at Seed and Series A stage. Most of the 42 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Lionheart Ventures's check size?
Lionheart Ventures typically joins rounds of $2.3M–$11M at Seed and $25k–$50M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Lionheart Ventures participates in.
How do I contact Lionheart Ventures?
Public channels for Lionheart Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Lionheart Ventures?
The team at Lionheart Ventures includes Shelby Clark (Partner, Mental Health), Annie Caton-Wong (Executive Assistant) and Brandon Goldman (Partner), among 9 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Sep 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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