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Lionheart Ventures, VC Fund

Lionheart Ventures

VC Fund

San Francisco, United States

Lionheart Ventures is a global, seed-stage venture capital firm focused on mitigating civilizational risk. We do this by supporting the wise development of transformative technologies. Our main areas of investment focus are transformative artificial intelligence and frontier mental health technologies.Leading academics estimate a 1-in-6 chance ofhuman extinction by the year 2100, largely driven by risks from emerging technologies. And now, with the exponential growth of AI, predictions are getting worse. Our startups are part of the solution. We invest in exceptional, ethical founders who are developing transformative technologies that have the potential to impact humanity on a meaningful scale, while generating attractive returns for our LPs.

Total investments:
42
Last investment:
Lead investor:
5%
Last fund:

Last updated:

Industries Lionheart Ventures invests in

Health CareBiotechnologyWellnessArtificial IntelligenceMental Health

Stages Lionheart Ventures invests in

SeedSeries APre-SeedFunding RoundVenture - Series Unknown

Countries Lionheart Ventures invests in

United StatesUnited KingdomGermanySingaporeCanada

Round sizes

Seed $2.3M–$11MSeries A $25k–$50M

Contacts

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Round size

Seed
$2.3M–$11M
Series A
$25k–$50M

Investment Focus

Industry

  • Health Care 13 (31%)
  • Biotechnology 7 (17%)
  • Wellness 6 (14%)
  • Artificial Intelligence 6 (14%)
  • Mental Health 5 (12%)
See all 69 industries →

Stage

  • Seed 27 (64%)
  • Series A 9 (21%)
  • Pre-Seed 1 (2%)
  • Funding Round 1 (2%)
  • Venture - Series Unknown 1 (2%)

Country

  • United States 25 (60%)
  • United Kingdom 5 (12%)
  • Germany 2 (5%)
  • Singapore 2 (5%)
  • Canada 1 (2%)
See all 8 countries →

Team

NameTitleInvestmentsLinksEmail
Shelby Clark
Shelby Clark Partner, Mental Health
Partner, Mental Health Total investments: 1
Find email
Annie Caton-Wong
Annie Caton-Wong Executive Assistant
Executive Assistant Total investments: 0
Find email
Brandon Goldman
Brandon Goldman Partner
Partner Total investments: 2
Find email
Carlos López Enríquez
Carlos López Enríquez VP of Finance
VP of Finance Total investments: 0
Find email
David Langer
David Langer Founding Partner
Founding Partner Total investments: 17
Find email
See all 9 team members →

Investments

CompanyDescriptionRoundLinks
Piramidal offers artificial intelligence software that transforms brain activity into easy-to-understand health data to help diagnose neurological diseases. $6M / Seed / Aug 21, 2024
Xylo Bio is a drug development company that focuses on next-generation psychedelics. With psychedelic molecules as the starting point, our goal is to develop medicines that are widely available as improved treatments to currently available SSRI medications. $3.2M / Seed / Oct 27, 2022
Clerkenwell Health is an innovative mental health company offering clinical research support services and psychedelic-assisted therapies. By providing independent psychedelic-specialist CRO services, Clerkenwell will accelerate the adoption of these treatments across Europe. The team are passionate about putting patients at the centre ofclinical trial design and delivering gold standard therapy protocols. $2.3M / Seed / Oct 10, 2022
Corporate mental health and emotional wellness platform for Latin America Seed / Sep 21, 2022
Trek Health builds foundational software that empowers mental health providers to start working with insurance networks. The company's contact modes are by mail, phone, and physical address. $2.7M / Seed / Sep 07, 2022
Cognigenics transforms mental health in the genetic age through cognitive neuroengineering. The company’s business is cognitive neuroengineering, which is the genetic engineering of desirable cognitive traits, such as mindfulness, relaxation, and mental acuity. These cognitive assets can enhance human performance in normal individuals or offsetcognitive deficits in people suffering from mental health issues such as stress, anxiety, and depression (which are the initial applications). $1.6M / Seed / Aug 16, 2022
Carbon Crusher offers carbon crushing as a service to the public or private road owners or contractors. It helps its clients identify problem areas and giving them long-term road security with end-to-end service and support along the way. Seed / Jun 09, 2022
Homecoming is a provider of patient engagement tools for psychedelic therapy. $4M / Seed / Apr 07, 2022
WellSet is the first platform to find, book and recommend wellness practitioners. Seed / Apr 07, 2022
The Breathwrk app offers easy to follow and highly effective guided breathing exercises that alleviate anxiety, promote sleep, increase energy, improve mood, help with athletic performance, and more! Seed / Apr 01, 2022
See all 42 investments →

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FAQ

What does Lionheart Ventures invest in?

Lionheart Ventures invests primarily in Health Care, Biotechnology and Wellness startups, most often at Seed and Series A stage. Most of the 42 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Lionheart Ventures's check size?

Lionheart Ventures typically joins rounds of $2.3M–$11M at Seed and $25k–$50M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Lionheart Ventures participates in.

How do I contact Lionheart Ventures?

Public channels for Lionheart Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Lionheart Ventures?

The team at Lionheart Ventures includes Shelby Clark (Partner, Mental Health), Annie Caton-Wong (Executive Assistant) and Brandon Goldman (Partner), among 9 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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