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Helena, VC Fund

Helena

VC Fund

Los Angeles, United States

Helena is a VC fund in Los Angeles focused on Health Care and Machine Learning. Helena Special Investments is an investment arm of Helena. It operates projects that implement solutions to societal problems through for-profit means.

Total investments:
9
Last investment:
Lead investor:
56%

Last updated:

Industries Helena invests in

Health CareMachine LearningArtificial IntelligenceEmailLegal

Stages Helena invests in

Series ASeries CSeries DFunding Round

Countries Helena invests in

United StatesSwitzerland

Round sizes

Series A $18M–$100MSeries C $100M–$155M

Round size

Series A
$18M–$100M
Series C
$100M–$155M

Investment Focus

Industry

  • Health Care 2 (22%)
  • Machine Learning 2 (22%)
  • Artificial Intelligence 2 (22%)
  • Email 1 (11%)
  • Legal 1 (11%)
See all 20 industries →

Stage

  • Series A 4 (44%)
  • Series C 2 (22%)
  • Series D 1 (11%)
  • Funding Round 1 (11%)

Country

  • United States 5 (56%)
  • Switzerland 1 (11%)

Investments

CompanyDescriptionRoundLinks
Lykos Therapeutics' goal is to revolutionize the way mental health is addressed. By creating innovative medicines and therapeutic techniques to treat mental health disorders, we hope to upend the status quo. With over thirty years of expertise investigating therapies aided by psychedelics, we continue to be committed to adhering to rigorousscience so that we can create and market innovative treatment alternatives. $100M / Series A / Jan 05, 2024
Twin Health is a Metabolic Health platform combining Sensors, AI, and Medical Science to reverse chronic diseases and improve human metabolic health. They are backed by leading VC firms Iconiq Capital, Temasek, Sequoia Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena, and Sofina with $249M in funding through Series D.Twinhas developed unique patent-pending technology (3 patents granted, 7 patents pending) to analyze complex biosignals from wearable sensors, predict metabolic outcomes using ML, and recommend highly-personalized treatments based on the metabolic profile of each patient. $50M / Series D / Dec 13, 2023
Phaidra provides AI and ML solutions to accelerate performance in large-scale industries. $25M / Series A / Jul 15, 2022
Aether Diamonds produces the world's first and only diamonds made 100% from captured carbon. Certified B Corp. 2022 Fast Company Top 10 Most Innovative Consumer Goods Companies. 2022 "Best for the World" B Corp. $18M / Series A / Mar 02, 2022
Aether captures carbon from the air and transforms it into diamonds. The company was founded in 2018 and based in New York. Series A / Mar 02, 2022
Aether Diamonds produces the world's first and only diamonds made 100% from captured carbon. Certified B Corp. 2022 Fast Company Top 10 Most Innovative Consumer Goods Companies. 2022 "Best for the World" B Corp. $18.3M / Series A / Mar 02, 2022
Twin Health is a Metabolic Health platform combining Sensors, AI, and Medical Science to reverse chronic diseases and improve human metabolic health. They are backed by leading VC firms Iconiq Capital, Temasek, Sequoia Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena, and Sofina with $249M in funding through Series D.Twinhas developed unique patent-pending technology (3 patents granted, 7 patents pending) to analyze complex biosignals from wearable sensors, predict metabolic outcomes using ML, and recommend highly-personalized treatments based on the metabolic profile of each patient. $155M / Series C / Oct 07, 2021
Energy Vault SA offers an energy storage technology utilizing fundamental principles of science to deliver a storage solution that's as compassionate to the planet as it is efficient to build and operate. The Energy Vault solution utilizes the same fundamentals of physics and kinetic energy as pumped hydro but replaces the water with custommade cylindrical blocks utilizing an extremely innovative use of low-cost materials.The system is modular and can be designed with a capacity of between 10 and 35MWh and a power output of up to 5MW. The system has been designed for a 30+ year life with no degradation in storage capacity. $100M / Series C / Aug 25, 2021
Energy Vault SA offers an energy storage technology utilizing fundamental principles of science to deliver a storage solution that's as compassionate to the planet as it is efficient to build and operate. The Energy Vault solution utilizes the same fundamentals of physics and kinetic energy as pumped hydro but replaces the water with custommade cylindrical blocks utilizing an extremely innovative use of low-cost materials.The system is modular and can be designed with a capacity of between 10 and 35MWh and a power output of up to 5MW. The system has been designed for a 30+ year life with no degradation in storage capacity. $20M / Venture - Series Unknown / Jul 20, 2021

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FAQ

What does Helena invest in?

Helena invests primarily in Health Care, Machine Learning and Artificial Intelligence startups, most often at Series A and Series C stage. Most of the 9 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Helena invest in?

Helena typically joins rounds of $18M–$100M at Series A and $100M–$155M at Series C. These are whole funding-round sizes, not Helena's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Helena took part in.

When did Helena last invest?

The most recent investment recorded for Helena closed in Jan 2024. Shizune tracks 9 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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