# Helena

> Helena is a VC fund in Los Angeles backing Health Care and Machine Learning. See 9 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Los Angeles, United States
- Total investments: 9
- Last investment: Jan 2024
- Lead investor: 56%
- Last updated: Aug 2026
- Website: http://helena.co

Helena is a VC fund in Los Angeles focused on Health Care and Machine Learning. Helena Special Investments is an investment arm of Helena. It operates projects that implement solutions to societal problems through for-profit means.

## Round sizes

| Stage | Round size |
| --- | --- |
| Series A | $18M–$100M |
| Series C | $100M–$155M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 2 | 22% |
| Machine Learning | 2 | 22% |
| Artificial Intelligence | 2 | 22% |
| Email | 1 | 11% |
| Legal | 1 | 11% |

20 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Series A | 4 | 44% |
| Series C | 2 | 22% |
| Series D | 1 | 11% |
| Funding Round | 1 | 11% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| United States | 5 | 56% |
| Switzerland | 1 | 11% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Lykos Therapeutics | Lykos Therapeutics' goal is to revolutionize the way mental health is addressed. By creating innovative medicines and therapeutic techniques to treat mental health disorders, we hope to upend the status quo. With over thirty years of expertise investigating therapies aided by psychedelics, we continue to be committed to adhering to rigorousscience so that we can create and market innovative treatment alternatives. | $100M | Series A | Jan 05, 2024 |  |
| Twin Health | Twin Health is a Metabolic Health platform combining Sensors, AI, and Medical Science to reverse chronic diseases and improve human metabolic health. They are backed by leading VC firms Iconiq Capital, Temasek, Sequoia Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena, and Sofina with $249M in funding through Series D.Twinhas developed unique patent-pending technology (3 patents granted, 7 patents pending) to analyze complex biosignals from wearable sensors, predict metabolic outcomes using ML, and recommend highly-personalized treatments based on the metabolic profile of each patient. | $50M | Series D | Dec 13, 2023 |  |
| Phaidra | Phaidra provides AI and ML solutions to accelerate performance in large-scale industries. | $25M | Series A | Jul 15, 2022 |  |
| Aether Diamonds | Aether Diamonds produces the world's first and only diamonds made 100% from captured carbon. Certified B Corp. 2022 Fast Company Top 10 Most Innovative Consumer Goods Companies. 2022 "Best for the World" B Corp. | $18M | Series A | Mar 02, 2022 |  |
| Aether | Aether captures carbon from the air and transforms it into diamonds. The company was founded in 2018 and based in New York. |  | Series A | Mar 02, 2022 |  |
| Aether Diamonds | Aether Diamonds produces the world's first and only diamonds made 100% from captured carbon. Certified B Corp. 2022 Fast Company Top 10 Most Innovative Consumer Goods Companies. 2022 "Best for the World" B Corp. | $18.3M | Series A | Mar 02, 2022 |  |
| Twin Health | Twin Health is a Metabolic Health platform combining Sensors, AI, and Medical Science to reverse chronic diseases and improve human metabolic health. They are backed by leading VC firms Iconiq Capital, Temasek, Sequoia Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena, and Sofina with $249M in funding through Series D.Twinhas developed unique patent-pending technology (3 patents granted, 7 patents pending) to analyze complex biosignals from wearable sensors, predict metabolic outcomes using ML, and recommend highly-personalized treatments based on the metabolic profile of each patient. | $155M | Series C | Oct 07, 2021 |  |
| Energy Vault | Energy Vault SA offers an energy storage technology utilizing fundamental principles of science to deliver a storage solution that's as compassionate to the planet as it is efficient to build and operate. The Energy Vault solution utilizes the same fundamentals of physics and kinetic energy as pumped hydro but replaces the water with custommade cylindrical blocks utilizing an extremely innovative use of low-cost materials.The system is modular and can be designed with a capacity of between 10 and 35MWh and a power output of up to 5MW. The system has been designed for a 30+ year life with no degradation in storage capacity. | $100M | Series C | Aug 25, 2021 |  |
| Energy Vault | Energy Vault SA offers an energy storage technology utilizing fundamental principles of science to deliver a storage solution that's as compassionate to the planet as it is efficient to build and operate. The Energy Vault solution utilizes the same fundamentals of physics and kinetic energy as pumped hydro but replaces the water with custommade cylindrical blocks utilizing an extremely innovative use of low-cost materials.The system is modular and can be designed with a capacity of between 10 and 35MWh and a power output of up to 5MW. The system has been designed for a 30+ year life with no degradation in storage capacity. | $20M | Venture - Series Unknown | Jul 20, 2021 |  |

9 of 9 investments shown.

## Co-investors
- [Helena](https://shizune.co/investors/profile/helena) — VC Fund, 8 deals together
- [ICONIQ Growth](https://shizune.co/investors/profile/iconiq-growth) — VC Fund, 2 deals together
- [Ketch Ventures](https://shizune.co/investors/profile/ketch-ventures) — VC Fund, 2 deals together
- [Khosla Ventures](https://shizune.co/investors/profile/khosla-ventures) — VC Fund, 2 deals together
- [Peak XV Partners](https://shizune.co/investors/profile/sequoia-india-2) — VC Fund, 2 deals together
- [Social Impact Capital](https://shizune.co/investors/profile/social-impact-capital) — VC Fund, 2 deals together

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## FAQ

### What does Helena invest in?

Helena invests primarily in Health Care, Machine Learning and Artificial Intelligence startups, most often at Series A and Series C stage. Most of the 9 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Helena's check size?

Helena typically joins rounds of $18M–$100M at Series A and $100M–$155M at Series C. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Helena participates in.

### When did Helena last invest?

The most recent investment recorded for Helena closed in Jan 2024. Shizune tracks 9 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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