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Friále, VC Fund

Friále

VC Fund

San Francisco, United States

Friále is a VC fund in San Francisco focused on Health Care and Software. Friále invest in start-ups all over the world who are doing big things. They act like the investors they would want as founders. They know what this is, because they are founders themselves. They usually invest at the seed stage, with the aim to follow-on as the company grows.

Total investments:
36
Last investment:
Lead investor:
3%

Last updated:

Industries Friále invests in

Health CareSoftwareInformation TechnologyMedicalFinancial Services

Stages Friále invests in

SeedPre-SeedSeries ASeries BFunding Round

Countries Friále invests in

United StatesIndiaCanadaNigeriaUnited Kingdom

Round sizes

Seed $1.2M–$4.2MPre-Seed $450k–$5MSeries A $3M–$20M

Contacts

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Round size

Seed
$1.2M–$4.2M
Pre-Seed
$450k–$5M
Series A
$3M–$20M

Investment Focus

Industry

  • Health Care 8 (22%)
  • Software 7 (19%)
  • Information Technology 6 (17%)
  • Medical 5 (14%)
  • Financial Services 5 (14%)
See all 70 industries →

Stage

  • Seed 24 (67%)
  • Pre-Seed 5 (14%)
  • Series A 4 (11%)
  • Series B 1 (3%)
  • Funding Round 1 (3%)

Country

  • United States 22 (61%)
  • India 2 (6%)
  • Canada 2 (6%)
  • Nigeria 2 (6%)
  • United Kingdom 2 (6%)

Team

NameTitleInvestmentsLinksEmail
Bryan Frist
Bryan Frist Founder & Managing Partner
Founder & Managing Partner Total investments: 16
Find email

Investments

CompanyDescriptionRoundLinks
Blaze is the smarter no-code platform for teams to build internal tools. Create beautiful client portals, admin panels, inventory management systems, and automated workflows without needing to write any code. Trusted by enterprise companies for security and scale. Loved by startup entrepreneurs for being so easy to use and build applications. $5M / Pre-Seed / Aug 03, 2026
Standard Practice is a force multiplier for healthcare providers. Never call insurance again. $8.5M / Seed / Jun 21, 2022
Annually, the wealthiest 300,000 people spend $1.3 million each on their lifestyle, but still struggle to find everything they want. - The most sought-after products, services, and experiences are never listed online. - Private events, private clubs, and numerous other categories are not accessible. - The best people don't need the web tofind clients or jobs. Myria is a private marketplace & community where all participants are fully vetted. Our offers are exclusive and otherwise unavailable online. Myria helps off-market sellers reach the nicest, richest, and most quailed buyers on Earth. In turn, we help the world’s most successful people find the best of everything and get the most out of life. $1.6M / Pre-Seed / Mar 21, 2022
Wallet.ng is a fintech startup that allows people and companies to send, receive, and make payments, using their phone numbers.The company's infrastructure also provides plugins and libraries for merchants to accept payments online with just a URL. Wallet.ng users can pay directly into bank accounts and Pay Utility Bills in Nigeria.Wallet.ng is a mobile payment solution, its core infrastructure is built using technologies which is adaptable for multiple countries across Africa.It was established in Lagos, Lagos by John Oluranti Oke and Joseph Benson-Aruna in 2018.. Jul 02, 2020
Wallets Africa helps Africans and African-owned businesses send money, receive money, make card payments, and access overdrafts. $1.3M / Seed / Jun 24, 2020
Eze Eze
Eze is a B2B Marketplace that connects telecommunication and global electronic wholesalers allowing them to trade devices in wholesale quantities with real-time market data. Our aim is to formalize the fragmented and inefficient second-hand electronics market that had an estimated beachhead of $46 billion.Buyers and sellers use our platform tosubmit buy and sell requests. Eze automatically connects the two parties with compatible bids and executes the trade. The platform gives businesses real-time market prices and eliminates transaction risk by acting as an intermediary with a secure payment system. $450K / Pre-Seed / Mar 16, 2020
BillionToOne is a precision diagnostics company that quantifies biology to create molecular diagnostics accurate, efficient, and accessible for all. The company's patent-pending molecular counter platform is a technology platform that can accurately count the DNA molecules to the single-count level. BillionToOne's mission is to makepre-natal testing safe and affordable for every expecting mother. Its novel technology can detect even single-gene disorders such as thalassemia through a simple blood test. They are replacing amniocentesis, an invasive and risky procedure that has a high miscarriage risk, with a safe and affordable blood test, starting in developing countries.BillionToOne was founded in 2016 and is headquartered in Menlo Park, California. $15M / Series A / Mar 10, 2020
C16 Biosciences is a biotechnology firm that uses microbiology to brew sustainable alternatives to palm oil.Utilizing its exclusive platform, the company is generating innovative ingredients without concessions for top global consumer goods manufacturers. Recently, they introduced the Palmless™ platform for sustainable ingredients, along withtheir inaugural biodesigned ingredient, Torula oil—a premium bioactive oil with clinically proven benefits for enhancing skin and hair health. $20M / Series A / Mar 02, 2020
Elpha is where women in tech to talk candidly online. Join Elpha to find support, connect personally and professionally with other women in the industry, make friends, build your network and search for jobs. Membership is free! $1.1M / Seed / Nov 06, 2019
Lively is a modern Health Savings Account (HSA) platform for employers and individuals. Lively’s user-centric solution creates an intuitive user experience allowing consumers to get the most out of their HSA. $27M / Series B / Oct 16, 2019
See all 36 investments →

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FAQ

What does Friále invest in?

Friále invests primarily in Health Care, Software and Information Technology startups, most often at Seed and Pre-Seed stage. Most of the 36 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Friále's check size?

Friále typically joins rounds of $1.2M–$4.2M at Seed, $450k–$5M at Pre-Seed and $3M–$20M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Friále participates in.

How do I contact Friále?

Public channels for Friále include the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Friále?

The team at Friále includes Bryan Frist (Founder & Managing Partner). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Sep 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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