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Dudi Klein, Co-Founder and Managing Partner at ALIVE Israel HealthTech Fund

Dudi Klein

Co-Founder and Managing Partner @ ALIVE Israel HealthTech Fund

Tel Aviv, Israel

Dudi Klein is a Series A investor at ALIVE Israel HealthTech Fund in Tel Aviv focused on Health Care and Medical. Highly passionate entrepreneurial executive, tenacious, results focused leader with 16+ years of experience - gets things done with limited resources under time constraints.I enjoy taking on new projects and challenges, have ability to successfully execute strategic products by bringing in highly set goals, business development and networkingskills that uplift the company and team, strong technical understanding and a keen eye for detail. I believe one of my major strengths is my ability and passion for motivation and coaching people for personal and corporate success.

Total investments:
3
Last investment:
Lead investor:
100%

Last updated:

Industries Dudi Klein invests in

Health CareMedicalmHealthMedical DeviceMobile Apps

Stages Dudi Klein invests in

Series ASeries BSeries C

Countries Dudi Klein invests in

United StatesIsrael

Contacts

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Investment Focus

Industry

  • Health Care 3 (100%)
  • Medical 2 (67%)
  • mHealth 2 (67%)
  • Medical Device 2 (67%)
  • Mobile Apps 1 (33%)
See all 8 industries →

Stage

  • Series A 1 (33%)
  • Series B 1 (33%)
  • Series C 1 (33%)

Country

  • United States 2 (67%)
  • Israel 1 (33%)

Investments

CompanyDescriptionRoundLinks
Append Medical develops a next-generation transcatheter Left Atrial Appendage (LAA) closure system.The Append Medical solution is in the pre-clinical in-vivo trial phase. It is intended to become a differentiated solution in the LAA closure market, which has been estimated to reach $25B within several years. This is the second-fastest growingsegment of the medical device market, with potential sales of $500M in 2019. Append Medical is a member of MEDX Xelerator, a medtech incubator backed by Boston Scientific, Intellectual Ventures, MEDX Ventures and Sheba Medical Center. $4.4M / Series A / Jul 06, 2023
Cynerio is a cybersecurity company focused on protecting healthcare environments, specifically targeting medical, clinical, IoT, and operational technology (OT) devices. Its unified platform includes three core modules: Network Detection and Response for Healthcare (NDR‑H), which offers deep packet inspection, real-time threat detection, andbehavioral anomaly responses; Medical Device Security, which automatically discovers connected devices, assesses risk, and provides mitigation strategies like micro-segmentation and patching; and Complete Asset Visibility, which delivers a centralized inventory of IT, OT, IoT, and IoMT devices with customizable dashboards and compliance reporting.The company integrates with Microsoft Sentinel and is a member of the Microsoft Intelligent Security Association (MISA), enhancing interoperability with cloud-native security operations platforms. Cynerio has received industry recognition, ranking among the top two vendors in the 2025 Best in KLAS report for Healthcare IoT Security with a score of 94 out of 100. It was also awarded Frost & Sullivan’s 2025 North American Enabling Technology Leadership Award.Cynerio's solutions are used globally, including deployments across major NHS trusts in the UK such as Barts Health and the Cheshire and Merseyside systems. These implementations helped rapidly identify unmonitored devices and apply proactive segmentation, significantly improving cybersecurity readiness in healthcare settings. $30M / Series B / May 19, 2021
Medisafe is a digital patient engagement platform, empowering patients to stay on top of all their medications. Its approach leverages the billions of data points collected to personalize patient engagement and improve adherence and persistence to medications.By addressing the major challenges of medication management utilizing a datascience-driven approach, Medisafe improves patient adherence and quality of care. The company provides its pharma and payer partners the opportunity to engage each patient on an individual level, supporting them throughout the entire patient journey, and provides unique insights on behavior patterns critical for improving the patient experience. Medisafe had shown over numerous studies, both retrospective with tens of thousands of patients as well as RCTs, that its solutions improve adherence by up to 20%.Founded following an accidental insulin overdose of the founder's father, the Medisafe solution currently has nearly 5 million registered users across iOS and Android smartphones, tablets, wearables, and Web solutions, who have recorded over 2 billion medication doses. Nearly 200,000 users have rated the app an average of 4.7 out of 5 stars in the App Store and Google Play store, making it the Top Rated solution in the category. Their accolades include Gartner Cool Vendors, Traction winner (Health 2.0 startup competition), Fast Company Most Innovative in Healthcare, Google and Apple Editors' Choice and Top Developer, etc. $30M / Series C / Feb 25, 2021

Co-Investors

ALIVE Israel HealthTech Fund

About ALIVE Israel HealthTech Fund

VC Fund · Tel Aviv, Israel

ALIVE Israel HealthTech Fund is a pioneer mid-to-late stage HealthTech fund leveraging an exclusive ecosystem.

ALIVE Israel HealthTech Fund Contacts

NameEmailPhoneSocials
Ari Shamiss
Ari Shamiss Co-Founder and Managing General Partner
Dudi Klein
Dudi Klein Co-Founder and Managing Partner
Dudi Klein
Dudi Klein Co-Founder and Managing Partner
Michel Habib
Michel Habib Co-Founder & Managing General Partner
Prof. Rafael Beyar
Prof. Rafael Beyar Co-Founder and Managing General Partner

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FAQ

What does Dudi Klein invest in?

Dudi Klein invests primarily in Health Care, Medical and mHealth startups, most often at Series A and Series B stage. Most of the 3 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Dudi Klein?

Public channels for Dudi Klein include LinkedIn and X (Twitter). For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Dudi Klein last invest?

The most recent investment recorded for Dudi Klein closed in Jul 2023. Shizune tracks 3 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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