Driehaus Capital Management
VC Fund
Chicago, United States
Driehaus Capital Management is a VC fund in Chicago focused on Biotechnology and Health Care. Driehaus is an investment management firm that manages growth equity investment strategies and multi-asset alternative strategies. The firm has a diverse institutional client base comprised of corporate and public pensions, endowments, foundations, sub-advisory, family offices, wealth managers, and financial advisors, globally. Driehaus is aperformance-oriented investment management boutique that emphasizes integrity, transparency, and the alignment of the firm’s interests with its clients.The firm was founded in 1982 and is headquartered in Chicago, Illinois.
- Total investments:
- 48
- Last investment:
- Lead investor:
- 0%
Last updated:
For AI agents: llms.txt
Industries Driehaus Capital Management invests in
Stages Driehaus Capital Management invests in
Countries Driehaus Capital Management invests in
Investment Focus
Industry
- Biotechnology 19 (40%)
- Health Care 16 (33%)
- Therapeutics 7 (15%)
- Pharmaceutical 7 (15%)
- Medical 6 (13%)
Stage
- Post-IPO Equity 11 (23%)
- Series B 5 (10%)
- Series C 3 (6%)
- Series A 2 (4%)
- Funding Round 2 (4%)
Country
- United States 21 (44%)
- Belgium 1 (2%)
- Switzerland 1 (2%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Entera Bio
|
Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience. | $275M / Post-IPO Equity / Jul 27, 2026 | |
Climb Bio
|
Eliem Therapeutics is a clinical-stage biotechnology company developing treatments for nervous system disorders. The company leverages its expertise in neuroscience, translational medicine, and clinical development to meet this unmet medical need with a highly innovative pipeline.Eliem Therapeutics develops and commercializes potentially“best-in-class” drug candidates to treat neuronal excitability disorders. These conditions—such as chronic pain, depression, epilepsy, and anxiety—cause deep suffering for tens of millions of people each day. At its core, the Eliem team is motivated by the promise of helping patients live happier, more fulfilling lives. | $110M / Post-IPO Equity / Apr 28, 2026 | |
Maze Therapeutics
|
Maze Therapeutics is a operator of a biotechnology firm intended to focused on translating genetic insights into new medicines. The company's translating genetic insights into new medicines by utilizing an approach that combines the analysis of large-scale human genetics data, functional genomics and an array of drug discovery approaches.andits also reveals modifier genes that confer protection and provides deeper understanding of the target biology and how these targets can be targeted with drug therapies, enabling patients with protection against diseases. | $150M / Post-IPO Equity / Apr 22, 2026 | |
Congruence Therapeutics
|
Congruence Therapeutics operates as a biotechnology company working at the interface of computational and experimental drug discovery to design novel small molecules for diseases of protein misfolding. | $39.5M / Venture - Series Unknown / Mar 19, 2026 | |
Alto Neuroscience
|
Alto Neuroscience is a clinical-stage biopharmaceutical company that integrates the biology of the patient into drug development to improve the lives of people with mental health conditions. Through its AI-enabled biomarker platform, Alto Neuroscience combines rich sources of information on patients’ brain activity and behavior to rapidly develophighly-effective medicines for targeted populations. Alto Neuroscience aims to replace today's trial-and-error clinical approach by aligning the right Alto drug with the right patient, redefining psychiatry at a time when the world needs it most. | $120M / Post-IPO Equity / Mar 16, 2026 | |
Korro Bio
|
Korro Bio provides an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms.Korro Bio was created to lead the field of RNA editing. The company is advancing a proprietary platform designed to selectively edit messenger RNA and recode specific codons to effect changes in proteinstructure and function across multiple tissues.In 2018, | $85M / Post-IPO Equity / Mar 09, 2026 | |
ALX Oncology
|
ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer. It is an independent, private biotechnology company.The founding of Alexo Therapeutics was based upon technology invented by Aaron Ring, K. Christopher Garcia, Kipp Weiskopf, Aron Levin, and Irving Weissman at Stanford University.This discovery involves soluble versions of signal regulatory protein-α (SIRPα) that have been engineered to bind CD47 with significantly greater affinity than natural SIRPα.1. | $150M / Post-IPO Equity / Jan 30, 2026 | |
Precision BioSciences
|
Precision BioSciences is a biotechnology company dedicated to improving lives through its next-generation gene editing technology, ARCUS.Precision BioSciences’ mission is to translate the world’s most powerful genome editing technology into greatly needed products throughout the life sciences. Precision’s proprietary ARCUS genome editingtechnology enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome. | $75M / Post-IPO Equity / Nov 10, 2025 | |
Relmada Therapeutics
|
Relmada Therapeutics is a late-stage biotechnology company addressing diseases of the central nervous system (CNS), with a focus on major depressive disorder (MDD). Our experienced and dedicated team is committed to making a difference in the lives of patients and their families. Relmada' s lead program, REL-1017, is a novel NMDA receptor(NMDAR) channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission. REL-1017 has entered late-stage development as an adjunctive treatment for MDD in adults.() | $100M / Post-IPO Equity / Nov 04, 2025 | |
|
Maze Therapeutics
|
Maze Therapeutics is a operator of a biotechnology firm intended to focused on translating genetic insights into new medicines. The company's translating genetic insights into new medicines by utilizing an approach that combines the analysis of large-scale human genetics data, functional genomics and an array of drug discovery approaches.andits also reveals modifier genes that confer protection and provides deeper understanding of the target biology and how these targets can be targeted with drug therapies, enabling patients with protection against diseases. | $150M / Post-IPO Equity / Sep 11, 2025 | |
| See all 48 investments → | |||
Co-Investors
Deep Track Capital
12 deals together
Janus Henderson Investors
11 deals together
OrbiMed
11 deals together
Perceptive Advisors
11 deals together
RA Capital Management
11 deals together
Venrock Healthcare Capital Partners
10 deals together
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FAQ
What does Driehaus Capital Management invest in?
Driehaus Capital Management invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Post-IPO Equity and Series B stage. Most of the 48 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
When did Driehaus Capital Management last invest?
The most recent investment recorded for Driehaus Capital Management closed in Jul 2026. Shizune tracks 48 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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