Define Ventures
VC Fund
San Francisco, United States
Define Ventures is an early-stage venture capital firm solely focused on investing in digital health companies. They partner with entrepreneurs with the digital health focus and expertise that they deserve to redefine healthcare.
- Total investments:
- 62
- Last investment:
- Lead investor:
- 31%
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Define Ventures invests in
Stages Define Ventures invests in
Countries Define Ventures invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 10 contacts → | |||
Round size
- Seed
- $3.2M–$8M
- Series A
- $10M–$35M
- Series B
- $15M–$140M
Investment Focus
Industry
- Health Care 27 (44%)
- Medical 12 (19%)
- Wellness 10 (16%)
- Information Technology 9 (15%)
- Software 6 (10%)
Stage
- Series A 18 (29%)
- Series B 17 (27%)
- Seed 13 (21%)
- Series C 4 (6%)
- Funding Round 2 (3%)
Country
- United States 29 (47%)
- United Kingdom 1 (2%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Chirag Shah
Partner
|
Partner | Total investments: 4 | Find email | |
Chuka Esiobu
Senior Associate and Investor
|
Senior Associate and Investor | Total investments: 0 | Find email | |
Garrett Howard
Senior Associate and Investor
|
Senior Associate and Investor | Total investments: 0 | Find email | |
Hong Truong
Principal
|
Principal | Total investments: 0 | Find email | |
Agneta Breitenstein
venture partner
|
venture partner | Total investments: 2 | Find email | |
| See all 10 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Nuance Labs, an AI research company, is developing the first human foundation model that understands and displays emotion in real time using voice, facial emotions, and body language. | $50M / Series A / Sep 14, 2026 | ||
| Arintra provides an AI-powered autonomous medical coding platform to streamline hospital and clinic revenue cycle management. The platform processes clinical documentation to generate accurate diagnostic and procedural codes (e.g., ICD‑10, CPT) within electronic health records like Epic or Cerner, requiring zero manual input. It offers explainableaudit trails and analytics dashboards that track coding accuracy, denial trends, and workflow efficiency. Clients report measurable improvements such as a 5% increase in revenue and over 50% reduction in aged accounts receivable days following implementation. | $25M / Series B / Aug 21, 2026 | ||
| Blank Bio develops a computational toolkit for RNA therapeutics that applies foundation models. | $7.2M / Seed / May 19, 2026 | ||
| 9amHealth is a virtual healthcare company focused on managing chronic cardiometabolic conditions such as diabetes, obesity, high blood pressure, and high cholesterol. The platform connects patients with licensed healthcare providers, pharmacists, nutritionists, prescription delivery services, and at-home laboratory testing through a digital caremodel. Its services include personalized treatment plans, medication management, ongoing monitoring, and remote consultations designed to support long-term condition management. The company also works with employers, health plans, and pharmacy benefit managers to provide healthcare support programs for individuals living with chronic illnesses. 9am.health’s care approach combines medical treatment, behavioral support, and digital tools to help patients access healthcare services remotely and manage their conditions more consistently. | $26M / Series B / May 12, 2026 | ||
| Luminai automates internal workflows by taking any multi-click process and making it one click. | $38M / Series B / Apr 09, 2026 | ||
| Valius Sciences offers maximalist oncology diagnostics for personalized cancer treatment. | $10M / Seed / Apr 09, 2026 | ||
| Hyro creates plug-and-play conversational AI assistants by seamlessly ingesting data on digital channels to allow users to interact with information via voice or chat simply and intuitively, allowing for increased engagement and conversions. Unlike existing solutions, Hyro provides organisations with frictionless deployment and maintenanceprocesses by automatically building a knowledge graph out of their existing content without any integration, playbooks, or training data. | $45M / Oct 21, 2025 | ||
| Foundation Health is a telehealth and nationwide pharmacies and diagnostic distribution centre | $20M / Series A / Oct 09, 2025 | ||
| Cohere Health is a healthcare technology company, focused on improving the efficiency and effectiveness of healthcare delivery. Cohere Health aims to simplify the complexities of the healthcare system by leveraging technology to streamline processes, enhance communication, and ultimately improve patient outcomes. The company may provide solutionsto various stakeholders in the healthcare ecosystem, including patients, providers, and payers. | $90M / Series C / May 14, 2025 | ||
| Layer Health focuses on resolving the healthcare information problem by utilizing artificial intelligence to execute any clinical, administrative, or research work that involves chart review from unstructured data. | $29.5M / Series A / Mar 27, 2025 | ||
| See all 62 investments → | |||
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FAQ
What does Define Ventures invest in?
Define Ventures invests primarily in Health Care, Medical and Wellness startups, most often at Series A and Series B stage. Most of the 62 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Define Ventures's check size?
Define Ventures typically joins rounds of $3.2M–$8M at Seed, $10M–$35M at Series A and $15M–$140M at Series B. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Define Ventures participates in.
How do I contact Define Ventures?
Public channels for Define Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Define Ventures?
The team at Define Ventures includes Chirag Shah (Partner), Chuka Esiobu (Senior Associate and Investor) and Garrett Howard (Senior Associate and Investor), among 10 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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