645 Ventures
VC Fund
New York, United States
645 Ventures is an early-stage venture capital firm that partners with exceptional founders who are building iconic companies. We invest at the Seed and Series A stages and leverage our Voyager software platform to enable our Success team and Connected Network to help founders scale to the growth stage. Select portfolio companies that have reached the growth stage include Iterable, Goldbelly, Resident, Eden Health, FiscalNote, and Squire. We invest in four main areas: SaaS for the Second Wave, Citizen Professionals, The Engineering Value Chain Revolution, and Personalized Consumer Applications. You can read more here: https://645ventures.com/themes/ 645 Ventures has $200m+ in AUM and is growing fast with backing from leading institutional investors, including university endowments, funds of funds, and pension funds. We have over 35 active companies in our portfolio in the areas of enterprise SaaS, infrastructure software, and consumer technology. Several of our portfolio companies have been acquired by Google, Facebook, Expedia, and private equity firms.
- Total investments:
- 156
- Last investment:
- Lead investor:
- 29%
- Fund size:
- $194M
- Last fund:
Last updated:
For AI agents: llms.txt
Industries 645 Ventures invests in
Stages 645 Ventures invests in
Countries 645 Ventures invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 17 contacts → | |||
Round size
- Seed
- $1.2M–$8.5M
- Series A
- $6.6M–$22M
- Series B
- $20M–$100M
Investment Focus
Industry
- Software 40 (26%)
- Artificial Intelligence 21 (13%)
- Information Technology 20 (13%)
- SaaS 17 (11%)
- Enterprise Software 11 (7%)
Stage
- Seed 67 (43%)
- Series A 43 (28%)
- Series B 12 (8%)
- Pre-Seed 7 (4%)
- Series C 3 (2%)
Country
- United States 93 (60%)
- United Kingdom 4 (3%)
- Spain 1 (1%)
- Mexico 1 (1%)
- Singapore 1 (1%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Alessio Fanelli
Principal, Investment & Research
|
Principal, Investment & Research | Total investments: 9 | Find email | |
Blake Jennelle
CTO In Residence
|
CTO In Residence | Total investments: 2 | Find email | |
Guerin Schwarberg
Vice President
|
Vice President | Total investments: 0 | Find email | |
Justin Fargione
Senior Full Stack Engineer
|
Senior Full Stack Engineer | Total investments: 0 | Find email | |
Matt Hawes
Associate
|
Associate | Total investments: 1 | Find email | |
| See all 17 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Lightsprint provides an AI-native product development platform that supports collaborative software development on a shared codebase. The platform offers a web-based workspace where product managers, designers, and engineers describe changes in plain English, review visual plans, and guide fleets of background coding agents. Its Visual Plan Modeturns requirements into structured task breakdowns, mockups, and codebase-aware specifications before any code is written. Parallel cloud agents then execute these plans in isolated environments, running tests and generating pull requests against existing repositories. Each change includes a live preview URL so non-technical teammates can review behavior before merge. Lightsprint is model- and tool-agnostic, integrates with systems such as GitHub, Linear, and Slack, and is designed to preserve institutional context about code patterns and product decisions over time. | $6.1M / Seed / Oct 13, 2026 | ||
| Gimlet Labs is an applied research lab focused on developing next-generation AI infrastructure. | $300M / Series B / Sep 04, 2026 | ||
| Rivo is a consumer fintech that sits on top of users’ existing bank accounts and automates idle cash management. It links to checking, keeps a user-set safe balance, sweeps excess cash into higher-yield instruments, and moves funds back before bills hit. | $2.7M / Seed / Aug 04, 2026 | ||
| Fish Audio is an AI platform for expressive text‑to‑speech and voice cloning with pro‑grade voices and multilingual support. | $52M / Seed / Jul 27, 2026 | ||
| Upside is the only nationally scalable housing stability platform purpose-built for healthcare. The company partners with health plans and employers to identify and stabilize members and employees experiencing housing instability, connecting them to safe, supportive housing while reducing avoidable emergency utilization and improving healthoutcomes. Upside pairs dedicated Care Guides with AI-supported housing orchestration to deliver measurable results at scale. The platform serves Medicaid, Medicare Advantage, D-SNP, commercial, and employer-sponsored populations across the full housing continuum, from crisis intervention to long-term tenancy support. Founded in 2020 and headquartered in Fort Lauderdale, FL, Upside is redefining how healthcare addresses housing as a foundation of care. | $20M / Series A / Jun 25, 2026 | ||
| Sekai is an AI‑powered content platform that enables users to create and live immersive, interactive stories | $20M / Series A / Jun 01, 2026 | ||
| AIVA is an intelligence layer for hotels. | $1.5M / Pre-Seed / Jun 01, 2026 | ||
| General Analysis provides a comprehensive suite of AI safety tools, including run-time guardrails, red-teaming frameworks and more. | $10M / Seed / Apr 29, 2026 | ||
| Pomo (pomohq) is a small, AI‑powered marketing‑tech startup that builds a unified platform of AI agents to plan, create, and optimize cross‑channel marketing campaigns for growth‑focused brands. It aims to replace fragmented tools and manual workflows with an integrated system that scales marketing operations and insights in one stack. | $4.5M / Seed / Apr 08, 2026 | ||
| Intrinsic is a software company that provides safety tools and API. | $21.5M / Series A / Mar 31, 2026 | ||
| See all 156 investments → | |||
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FAQ
What does 645 Ventures invest in?
645 Ventures invests primarily in Software, Artificial Intelligence and Information Technology startups, most often at Seed and Series A stage. Most of the 156 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What round sizes does 645 Ventures invest in?
645 Ventures typically joins rounds of $1.2M–$8.5M at Seed, $6.6M–$22M at Series A and $20M–$100M at Series B. These are whole funding-round sizes, not 645 Ventures's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds 645 Ventures took part in.
How do I contact 645 Ventures?
Public channels for 645 Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at 645 Ventures?
The team at 645 Ventures includes Alessio Fanelli (Principal, Investment & Research), Blake Jennelle (CTO In Residence) and Guerin Schwarberg (Vice President), among 17 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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