# Zcube

> Zcube is a VC fund in Bresso backing Health Care and Medical Device. See 5 investments, check sizes, portfolio and contact details. Updated Aug 2026.

- Type: VC Fund
- Location: Bresso, Italy
- Total investments: 5
- Last investment: Sep 2024
- Lead investor: 60%
- Last updated: Aug 2026
- X (Twitter): https://www.twitter.com/cubeaccelerator
- Website: https://www.zambon.com/en/innovation/zcube

Zcube is a VC fund in Bresso focused on Health Care and Medical Device. Zcube is the Research Venture of the Zambon Group. It was established in 2003 to explore innovation and research in the Life Science field on a global level. Zcube has three work streams: Zcare, Open Accelerator, investments in national and international funds. It supports the development and acceleration of innovative startups

## Contacts

5 contacts available for Zcube. Shizune tracks 2 team members at Zcube. Sign up free to unlock them: https://app.shizune.co/sign-up/investor-profiles/find-team-emails/z-cube?utm_source=investor_profile

## Round sizes

| Stage | Round size |
| --- | --- |
| Seed | $56k–$1.5M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 2 | 40% |
| Medical Device | 2 | 40% |
| Medical | 1 | 20% |
| mHealth | 1 | 20% |
| Biopharma | 1 | 20% |

10 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 2 | 40% |
| Pre-Seed | 1 | 20% |
| Series B | 1 | 20% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| Italy | 1 | 20% |
| Canada | 1 | 20% |
| Lithuania | 1 | 20% |

## Team

| Name | Title | Investments | Profile |
| --- | --- | --- | --- |
| Elena Zambon | President | 2 | https://shizune.co/investors/profile/elena-zambon |
| Orientina Di Giovanni | Chief of Zcare Division | 0 | https://shizune.co/investors/profile/orientina-di-giovanni |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Hyivy Health | Hyivy Health creates an intelligent and holistic pelvic rehabilitation device for the 1 in 3 women worldwide who will experience a pelvic health complication in their lifetime. Our device provides the first quantifiable data set on the pelvic floor and 3 different therapies from multiple sensors and mechanical functions to help keep track ofprogress, adapt treatment plans and provide more effective, comfortable rehab experiences. | $1.5M | Seed | Sep 24, 2024 |  |
| Hyivy Health | Hyivy Health creates an intelligent and holistic pelvic rehabilitation device for the 1 in 3 women worldwide who will experience a pelvic health complication in their lifetime. Our device provides the first quantifiable data set on the pelvic floor and 3 different therapies from multiple sensors and mechanical functions to help keep track ofprogress, adapt treatment plans and provide more effective, comfortable rehab experiences. | $1.5M | Seed | Sep 24, 2024 |  |
| Vilimed | Vilimed specialises in the development of medical devices like Vilim ball which is a therapeutic device developed for hand tremor reduction. | $55.6K | Seed | Mar 02, 2022 |  |
| Hyivy Health | Hyivy Health creates an intelligent and holistic pelvic rehabilitation device for the 1 in 3 women worldwide who will experience a pelvic health complication in their lifetime. Our device provides the first quantifiable data set on the pelvic floor and 3 different therapies from multiple sensors and mechanical functions to help keep track ofprogress, adapt treatment plans and provide more effective, comfortable rehab experiences. | $1M | Pre-Seed | Jan 18, 2022 |  |
| PharmEste | PharmEste s.r.l., a biopharmaceutical company, engages in the discovery and development of transient receptor potential (TRP) channel therapeutics for the treatment of neuropathic pain, overactive bladder, and other TRP-mediated diseases. It develops PHE377, a TRPV1 antagonist for the treatment of neuropathic pain. | $5.3M | Series B | Jun 01, 2011 |  |

5 of 5 investments shown.

## Co-investors
- [Beresford Ventures](https://shizune.co/investors/profile/beresford-ventures) — VC Fund, 3 deals together
- [Equation Angels](https://shizune.co/investors/profile/equation-angels) — VC Fund, 3 deals together
- [Chai Ventures](https://shizune.co/investors/profile/chai-ventures) — VC Fund, 2 deals together
- [FACIT](https://shizune.co/investors/profile/facit-prospects-oncology-fund) — VC Fund, 2 deals together
- [mHUB](https://shizune.co/investors/profile/mhub-3) — VC Fund, 2 deals together
- [Women's Equity Lab](https://shizune.co/investors/profile/women-s-equity-lab) — VC Fund, 2 deals together

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## FAQ

### What does Zcube invest in?

Zcube invests primarily in Health Care, Medical Device and Medical startups, most often at Seed and Pre-Seed stage. Most of the 5 investments tracked by Shizune back companies in Italy. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Zcube's check size?

Zcube typically joins rounds of $56k–$1.5M at Seed. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Zcube participates in.

### How do I contact Zcube?

Public channels for Zcube include X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

### Who are the partners at Zcube?

The team at Zcube includes Elena Zambon (President) and Orientina Di Giovanni (Chief of Zcare Division). The Team section lists each member with their title, investment count and links.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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