# Wireframe Ventures

> Wireframe Ventures is a VC fund backing Biotechnology and Software. See 59 investments, check sizes, portfolio and contact details. Updated Aug 2026.

- Type: VC Fund
- Location: Mill Valley, United States
- Total investments: 59
- Last investment: Apr 2026
- Lead investor: 29%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/wireframe-ventures
- X (Twitter): https://twitter.com/WireframeVC
- Website: http://www.wireframevc.com/

Wireframe Ventures is a venture capital firm investing at the seed and pre-seed stage. We back missionary founders using technology to positively impact people & planet.

## Contacts

5 contacts available for Wireframe Ventures. Shizune tracks 3 team members at Wireframe Ventures. Sign up free to unlock them: https://app.shizune.co/sign-up/investor-profiles/find-team-emails/wireframevc?utm_source=investor_profile

## Round sizes

| Stage | Round size |
| --- | --- |
| Seed | $2.3M–$11M |
| Pre-Seed | $120k–$5.5M |
| Series A | $8.5M–$51M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Biotechnology | 9 | 15% |
| Software | 8 | 14% |
| SaaS | 4 | 7% |
| Energy | 4 | 7% |
| Therapeutics | 4 | 7% |

72 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 28 | 47% |
| Series A | 15 | 25% |
| Pre-Seed | 4 | 7% |
| Series B | 3 | 5% |
| Venture - Series Unknown | 3 | 5% |

6 stages tracked in total.

### Country

| Country | Investments | Share |
| --- | --- | --- |
| United States | 34 | 58% |
| United Kingdom | 3 | 5% |

## Team

| Name | Title | Investments | Profile |
| --- | --- | --- | --- |
| Lily Bernicker | Principal | 3 | https://shizune.co/investors/profile/lily-bernicker |
| Harsh Patel | Co-Founder & Managing Partner | 4 | https://shizune.co/investors/profile/harsh-patel-3 |
| Paul Straub | Managing Partner, Director & Co-founder | 14 | https://shizune.co/investors/profile/paul-straub |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Sora Fuel | Sora Fuel makes jet fuel from just air, water, and renewable energy. Sora Fuel combine carbon capture and utilization into a single process, dramatically reducing the amount of energy required to produce SAF, enabling a truly affordable, carbon-negative drop-in solution. | $14.6M | Venture - Series Unknown | Apr 08, 2026 |  |
| Cocoon | Cocoon provides environmental consulting services to businesses and develops solutions to analyze and eradicate industrial waste. | $15M | Series A | Mar 18, 2026 |  |
| Great Sky | Great Sky combines photonics, superconductors, and semiconductors. to develop AI hardware. | $14M | Seed | Mar 14, 2026 |  |
| Ezra | Ezra is an AI-powered infrastructure platform built to transform capital markets. By replacing manual processes with automated data structuring and smart matching, it helps operators raise capital and lenders deploy funds efficiently within the private credit and project finance landscapes. | $8M | Seed | Feb 25, 2026 |  |
| C.Scale | C.Scale is predictive SaaS enabling zero carbon building at scale. Our lightweight AI and ML models democratizes access to data around carbon mitigation strategies without the high cost of expert consulting or full-time salaried experts. When highly-detailed energy modeling and life cycle assessment aren't affordable or practicable, teams useC.Scale.C.Scale is the data model behind our open access and free Early-Phase Integrated Carbon Assessment tool (EPIC) currently helping 4,000+ users aim for carbon neutrality in their buildings, and available for all at epic.ehdd.com. We developed EPIC internally at the architecture firm EHDD to solve a problem that we had as we moved away from net zero energy design towards zero carbon design. There were no tools available to get us beyond intuition in weighing embodied and operational carbon decisions early in the design process. EPIC solved that problem so well that we decided to share it freely with the world in order to increase the speed and scale of climate impact the tool could have.C.Scale enables the full range of actors in the built environment low-friction access to data and insights in an intuitive and welcoming user interface. In this way we are democratizing access to data and expertise. Currently only design firms and owners willing and able to invest the time and money into custom consulting or detailed analysis are able to integrate data-driven insights into their work. Climate action should not and cannot be the domain of the few if we are to meet our climate action targets.C.Scale is an outgrowth of the culture of innovation at EHDD, an architecture firm with offices in San Francisco and Seattle. | $2M | Pre-Seed | Nov 04, 2025 |  |
| Argon AI | Argon AI is a platform that allows biopharmacy and life sciences experts to conduct complicated, data-driven operations using natural language. Argon AI helps professionals acquire detailed answers to inquiries about clinical trials, existing medicines, the healthcare landscape, and the competitive market in minutes, not months. | $5.5M | Seed | Jul 02, 2025 |  |
| Tyba | Tyba provides end-to-end modeling of standalone and hybrid storage projects from early-stage development through operations, giving your business the edge to build and operate the best projects faster and more profitably. | $13.9M | Series A | Feb 06, 2025 |  |
| Bedrock Energy | Bedrock Energy is developing drilling technology and advanced subsurface simulation software to enable geothermal heating and cooling. The company develops autonomous drilling technology and advanced subsurface simulation software to make geothermal heating and cooling more widespread, affordable, and accessible. | $12M | Series A | Jan 22, 2025 |  |
| Passkey | Passkey Therapeutics is pioneering a new class of medicines, Synergistic Multifunctional Therapeutics (SMThs). It is designed to address complex diseases by targeting rare combinations of proteins that work together. | $20M | Seed | Oct 22, 2024 |  |
| Cocoon | Cocoon provides environmental consulting services to businesses and develops solutions to analyze and eradicate industrial waste. | $5.4M | Pre-Seed | Aug 08, 2024 |  |

10 of 59 investments shown.

## Co-investors
- [True Ventures](https://shizune.co/investors/profile/true-ventures) — VC Fund, 6 deals together
- [Congruent Ventures](https://shizune.co/investors/profile/congruent-ventures) — VC Fund, 5 deals together
- [Mayfield Fund](https://shizune.co/investors/profile/mayfield-fund) — VC Fund, 5 deals together
- [Prelude Ventures](https://shizune.co/investors/profile/prelude-ventures-llc) — VC Fund, 5 deals together
- [SOSV](https://shizune.co/investors/profile/sosv) — VC Fund, 5 deals together
- [Celsius Industries](https://shizune.co/investors/profile/celsius-industries) — VC Fund, 4 deals together

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## FAQ

### What does Wireframe Ventures invest in?

Wireframe Ventures invests primarily in Biotechnology, Software and SaaS startups, most often at Seed and Series A stage. Most of the 59 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Wireframe Ventures's check size?

Wireframe Ventures typically joins rounds of $2.3M–$11M at Seed, $120k–$5.5M at Pre-Seed and $8.5M–$51M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Wireframe Ventures participates in.

### How do I contact Wireframe Ventures?

Public channels for Wireframe Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

### Who are the partners at Wireframe Ventures?

The team at Wireframe Ventures includes Lily Bernicker (Principal), Harsh Patel (Co-Founder & Managing Partner) and Paul Straub (Managing Partner, Director & Co-founder). The Team section lists each member with their title, investment count and links.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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