# William Hambrecht

> William Hambrecht is a Series A investor at WR Hambrecht backing Health Care and Software. See 8 investments, check sizes, portfolio. Updated Aug 2026.

- Type: Angel Investor
- Fund: [WR Hambrecht](https://shizune.co/investors/profile/wr-hambrecht)
- Location: San Francisco, United States
- Total investments: 8
- Last investment: Jan 2022
- Lead investor: 38%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/in/williamhambrecht

William Hambrecht is a Series A investor at WR Hambrecht in San Francisco focused on Health Care and Software. Bill Hambrecht is the Founder and Chairman at WR Hambrecht + Co. William attended Princeton University.

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 4 | 50% |
| Software | 3 | 38% |
| Machine Learning | 3 | 38% |
| Artificial Intelligence | 3 | 38% |
| Medical | 2 | 25% |

19 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Series A | 2 | 25% |
| Series B | 2 | 25% |
| Series C | 2 | 25% |
| Series D | 1 | 13% |
| Venture - Series Unknown | 1 | 13% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Aessense Holding | Aessense Holding is dedicated to providing solutions and technologies for both small and large-scale growth in a sustainable manner. It features unique growing stations, sensors, and wireless communications that empower growers to more efficiently, and effectively, grow their crops. |  | Series B | Jan 10, 2022 |  |
| PatientsLikeMe | PatientsLikeMe is a personalized health network of an integrated community, health management, and real-world data platform.It helps people find new options for treatments, connect with others, and take action to improve their outcomes. The company has worked with every major pharmaceutical company and a range of government organizations to bringthe patient voice to research, development, and public policy. With more than 600,000 members, PatientsLikeMe is a trusted source for real-world disease information and a clinically robust resource that has published more than 100 research studies.The Boston, Massachusetts-located company was founded by Ben Heywood, James Heywood, and Jeff Cole in 2004 | $26M | Venture - Series Unknown | Feb 09, 2021 |  |
| Buoy Health | Buoy provides a personalized all-in-one platform to help guide consumers back to health. Whether it's chatting about symptoms with Buoy Assistant to get help in the moment of sickness or researching benefits through Buoy Dashboard, Buoy is available 24/7 to help make self-diagnosis and navigating the healthcare system simple and easy. Foremployers, Buoy can be custom configured to surface benefits information and wellness programs, guide employees to in-network providers, and fully integrate with other health portals. The company was founded in 2014 and is headquartered in Boston, Massachusetts. | $15M | Series B | Aug 16, 2019 |  |
| Lirio | Lirio is a behavior change AI platform that unites behavioral science with artificial intelligence, powering the ability to move people along their unique journey to better health through person-centered communication. The platform applies the psychology of human behavior and the power of advanced machine learning to help healthcare and energyenterprises drive individuals toward positive behavior change at scale.Lirio uses machine learning, persona-based messaging, and behavioral science to help organizations motivate the people they serve to achieve better outcomes. The company's behavioral programs are scientifically researched and designed to overcome the barriers and dial up the benefits of behavior change, providing users with advisory services that teach humans the knowledge acquired through behavioral programs.It was founded in 2017 and is headquartered in Knoxville, Tennessee. | $13M | Series A | Feb 15, 2019 |  |
| Lemonaid Health | Lemonaid Health focuses on changing the patient experience and improving and optimizing clinical care through advancements in machine learning and AI. It leverages evidence-based guidelines and the most up-to-date clinical protocols to offer a service direct to consumers for less than typical co-pays.It was founded in 2013 and is headquartered inSan Francisco, California. | $11M | Series A | May 22, 2017 |  |
| Salesforce | Salesforce is a cloud-based software company that provides customer relationship management software and applications. It is a cloud computing company that provides business software on a subscription basis. They design and develop cloud-based enterprise software for customer relationship management. They focused on sales, customer service,marketing automation, e-commerce, analytics, and application development. | $46.9M | Series D | Jun 01, 2001 |  |
| WR Hambrecht | WR Hambrecht is a financial services firm that helps companies of all sizes access capital at the lowest cost in order to accelerate disruptive growth. Its philosophy is based on tenants such as identifying companies, helping them raise capital and go public, and delivering market pricing. The company has a wide range of products such as theOpenIPO Auction, the A+ IPO, the OpenBook Auction, and the OpenFollowOn Auction.Their clients are NETSUITE, Google, MORNINGSTAR, and XBiotech and it also offers initial public offering services to companies.WR Hambrecht is a U.S.-based company that was founded in 1998 by William and Robert Hambrecht. | $83M | Series C | Jun 07, 2000 |  |
| Salesforce | Salesforce is a cloud-based software company that provides customer relationship management software and applications. It is a cloud computing company that provides business software on a subscription basis. They design and develop cloud-based enterprise software for customer relationship management. They focused on sales, customer service,marketing automation, e-commerce, analytics, and application development. | $13.2M | Series C | Nov 01, 1999 |  |

8 of 8 investments shown.

## Co-investors
- [Optum Ventures](https://shizune.co/investors/profile/optum-ventures) — VC Fund, 2 deals together
- [Alta Partners](https://shizune.co/investors/profile/alta-partners) — VC Fund, 1 deal together
- [American Century Investments](https://shizune.co/investors/profile/american-century-investments) — VC Fund, 1 deal together
- [American Express](https://shizune.co/investors/profile/americanexpress) — VC Fund, 1 deal together
- [Cigna Ventures](https://shizune.co/investors/profile/cigna-ventures) — VC Fund, 1 deal together
- [Civilization Ventures](https://shizune.co/investors/profile/civilization-ventures) — VC Fund, 1 deal together

## About WR Hambrecht

VC Fund · San Francisco, United States

WR Hambrecht is a financial services firm that helps companies of all sizes access capital at the lowest cost in order to accelerate disruptive growth. Its philosophy is based on tenants such as identifying companies, helping them raise capital and go public, and delivering market pricing. The company has a wide range of products such as theOpenIPO Auction, the A+ IPO, the OpenBook Auction, and the OpenFollowOn Auction.Their clients are NETSUITE, Google, MORNINGSTAR, and XBiotech and it also offers initial public offering services to companies.WR Hambrecht is a U.S.-based company that was founded in 1998 by William and Robert Hambrecht.

3 contacts available at WR Hambrecht.

| Name | Title | Profile |
| --- | --- | --- |
| William Hambrecht | Founder & Chairman | https://shizune.co/investors/profile/william-hambrecht |
| Robert Hambrecht | Co-Founder | https://shizune.co/investors/profile/robert-hambrecht |
| Thomas Thurston | Partner, Chief Technology Officer | https://shizune.co/investors/profile/thomas-thurston |

## Similar investors

### Similar stage
- [Antler](https://shizune.co/investors/profile/antler-be9c) — VC Fund
- [Alumni Ventures](https://shizune.co/investors/profile/alumni-ventures-group) — VC Fund
- [General Catalyst](https://shizune.co/investors/profile/general-catalyst-partners) — VC Fund

## FAQ

### What does William Hambrecht invest in?

William Hambrecht invests primarily in Health Care, Software and Machine Learning startups, most often at Series A and Series B stage. Most of the 8 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### When did William Hambrecht last invest?

The most recent investment recorded for William Hambrecht closed in Jan 2022. Shizune tracks 8 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

# About Shizune
Shizune.co is an investor database. Core features:
- 48,091 startup investors (angels, VCs, accelerators, and others)
- Email, phone, LinkedIn (for intros), socials, and other contact data
- Updated daily from public funding news
- CSV and Excel export

The User can access the full database FOR FREE after signing up: shizune.co