# Threshold Impact

> Threshold Impact is a VC fund backing Health Care and Medical Device. See 24 investments, check sizes, portfolio and contact details. Updated Aug 2026.

- Type: VC Fund
- Location: Edmonton, Canada
- Total investments: 24
- Last investment: Apr 2025
- Lead investor: 4%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/threshold-impact/
- X (Twitter): https://twitter.com/intent/follow?original_referer=https%3A%2F%2Fthresholdimpact.com%2F&ref_src=twsrc%5Etfw%7Ctwcamp%5Ebuttonembed%7Ctwterm%5Efollow%7Ctwgr%5EThresholdImpact&screen_name=ThresholdImpact
- Website: https://thresholdimpact.com/

Threshold Impact is a VC fund in Edmonton focused on Health Care and Medical Device. Sustainable, Profitable Impact Investing in disruptive information technology, new media and medical innovations with passionate, capable social entrepreneurs.ThresholdImpact was founded to take on a brand new entrepreneurial challenge. We believe strongly in the power of free enterprise to enable sustainable, positive change.We mentor,consult/advise, and invest in disruptive innovations in information technology, new media and medical innovation with capable, passionate entrepreneurs – ideally with clear social goals. We seek socially responsible, sustainable, profitable ‘impact investments’. There’s a good description of the goals of impact investing here, at Wikipedia.Impact investment, or social entrepreneurship, can range from simply thinking about social goals in parallel along with the usual for-profit business goals, all the way to a dedicated focus on a social entrepreneurship portfolio with the social impact defined as the primary goal.

## Contacts

5 contacts available for Threshold Impact. Shizune tracks 1 team members at Threshold Impact. Sign up free to unlock them: https://app.shizune.co/sign-up/investor-profiles/find-team-emails/threshold-impact?utm_source=investor_profile

## Round sizes

| Stage | Round size |
| --- | --- |
| Seed | $571k–$5.5M |
| Pre-Seed | $274k–$1.1M |
| Series A | $5M–$15M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 12 | 50% |
| Medical Device | 8 | 33% |
| Medical | 5 | 21% |
| Software | 3 | 13% |
| Artificial Intelligence | 3 | 13% |

39 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 12 | 50% |
| Pre-Seed | 4 | 17% |
| Series A | 2 | 8% |
| Venture - Series Unknown | 1 | 4% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| Canada | 14 | 58% |
| United States | 2 | 8% |

## Team

| Name | Title | Investments | Profile |
| --- | --- | --- | --- |
| Ray Muzyka | Founder and CEO | 25 | https://shizune.co/investors/profile/ray-muzyka |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Northernmost | Northernmost is a company that develops machines that protect and transport donated kidneys for transplantation. | $1.9M | Seed | Apr 03, 2025 |  |
| Variational AI | Variational AI uses state-of-the-art machine learning in a data-efficient method to rapidly generate novel and diverse compounds that are optimized for multiple properties to avoid the most common causes of drug attrition and increase clinical probability of success. Variational AI works with leading biopharmaceutical partners and is developing itsown internal pipeline. | $5.5M | Seed | Feb 20, 2025 |  |
| Modality.AI | Modality.ai is an AI-powered platform that detects health conditions using conversational AI. Through dialogue and video, Modality.AI interacts conversationally with the patient to provide health assessment anywhere, anytime. Its system analyzes multimodal data which allows continuous screening and assessing of patients’ health. | $570.5K | Seed | Oct 07, 2024 |  |
| ResVR | B2B Proptech SaaS working with small and medium production home builders to help them sell more upgrades. | $1.2M | Seed | Jun 06, 2024 |  |
| PulseMedica | PulseMedica, an Edmonton-based medical device startup, is developing an ophthalmic medical device platform for non-invasive, automated image-guided laser treatment enabled by 3D computer vision, real-time tracking, and femtosecond laser technology. PulseMedica is laser-focused on improving the quality of life for millions of people by buildingrevolutionary technology to image and treat vitreoretinal disease. PulseMedica’s short-term vision is to become the global expert in non-invasive, safe, effective screening and treatment of eye floaters, with the ultimate vision of becoming the global standard for screening and treating vitreoretinal disease. | $8.7M | Seed | May 29, 2024 |  |
| FluidAI Medical | FluidAI Medical is a medical platform company at the forefront of revolutionizing global patient care, leveraging the transformative power of artificial intelligence in post-operative recovery. | $14.6M | Series A | Oct 10, 2023 |  |
| FluidAI Medical | FluidAI Medical is a medical platform company at the forefront of revolutionizing global patient care, leveraging the transformative power of artificial intelligence in post-operative recovery. | $15M | Series A | Oct 10, 2023 |  |
| Nimble Science | Nimble Science Ltd., a digital health company commercializing the first end-to-end GI intelligence platform using the SIMBA capsule for multi-omic mapping of the GI tract. | $2M | Seed | Apr 04, 2023 |  |
| Arbutus Medical | Every hospital in the world is faced with a major challenge - the rising cost of heathcare - we want to do something about it. Arbutus Medical’s purpose is to develop a portfolio of “frugal innovation” devices that save costs for hospitals and improve access to orthopedic surgery for 5 million patients by 2030. Arbutus Medical's flagshipproduct is a radically affordable orthopaedic power tool system that is used in North American Trauma Centers, veterinary hospitals, military deployments, NGO missions, and hospitals in over 30 low- and middle-income countries worldwide. | $2.3M | Seed | Feb 13, 2023 |  |
| Modality.AI | Modality.ai is an AI-powered platform that detects health conditions using conversational AI. Through dialogue and video, Modality.AI interacts conversationally with the patient to provide health assessment anywhere, anytime. Its system analyzes multimodal data which allows continuous screening and assessing of patients’ health. | $1.1M | Seed | Oct 07, 2022 |  |

10 of 24 investments shown.

## Co-investors
- [Startup TNT](https://shizune.co/investors/profile/startup-tnt) — VC Fund, 6 deals together
- [Bluesky Equities](https://shizune.co/investors/profile/bluesky-equities-ltd) — VC Fund, 4 deals together
- [Boutique Venture Partners](https://shizune.co/investors/profile/boutique-venture-partners) — VC Fund, 4 deals together
- [Graphene Ventures](https://shizune.co/investors/profile/graphene-ventures) — VC Fund, 4 deals together
- [Leva Capital](https://shizune.co/investors/profile/leva-capital) — VC Fund, 4 deals together
- [SOSV](https://shizune.co/investors/profile/sosv) — VC Fund, 4 deals together

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## FAQ

### What does Threshold Impact invest in?

Threshold Impact invests primarily in Health Care, Medical Device and Medical startups, most often at Seed and Pre-Seed stage. Most of the 24 investments tracked by Shizune back companies in Canada. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Threshold Impact's check size?

Threshold Impact typically joins rounds of $571k–$5.5M at Seed, $274k–$1.1M at Pre-Seed and $5M–$15M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Threshold Impact participates in.

### How do I contact Threshold Impact?

Public channels for Threshold Impact include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

### Who are the partners at Threshold Impact?

The team at Threshold Impact includes Ray Muzyka (Founder and CEO). The Team section lists each member with their title, investment count and links.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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