# SF500

> SF500 is a VC fund in Rosario backing Medical, Biopharma and Biotechnology. See 23 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Rosario, Argentina
- Total investments: 23
- Last investment: Nov 2024
- Lead investor: 91%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/sf500
- Website: https://x.com/sf500f?lang=en

SF500 is a BioTech accelerator and VC fund. Founded in 2022. We turn science projects into Biotech startups. We search for outstanding science ideas and strong scientific and business people to build successful teams. We run a 12-week intensive program for 15 candidates with focus on science, team and product. A selection of the participants of ourprogram receive a pre-seed investment of $200k. Our in-house dedicated portfolio management team keeps working with the founders, supporting all our portfolio startups from investment to the next stages. From legal and IP services to peer-to-peer support, lab facilities and connections to our network of international investors.

## Round sizes

| Stage | Round size |
| --- | --- |
| Pre-Seed | $250k–$500k |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Medical | 1 | 4% |
| Biopharma | 1 | 4% |
| Biotechnology | 1 | 4% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| PILL.AR | PILL.AR is a biotechnology company that offers personalised medication for people. | $250K | Pre-Seed | Nov 06, 2024 |  |
| NotFossil | NotFossil is a biotechnology company that offers hydrocarbon bioremediation services for wastewater treatment. | $250K | Pre-Seed | Jul 30, 2024 |  |
| Gameet | Gameet is a biotechnology startup that emulates the natural processes of sperm selection and growth in a device printed with 3D technology. | $250K | Pre-Seed | Jul 08, 2024 |  |
| Tintte | We revolutionize the textile dyeing industry, innovating the way of creating colors and dyeing. We apply biotechnology to specifically selected bacteria to produce Bio dyes and Bio compounds. We eliminate the use of chemicals, toxics and reduce the use of drinking water and energy. | $450K | Pre-Seed | Apr 24, 2024 |  |
| MesencHyal-T | MesencHyal-T is a biotechnology company that develops cellular medical therapies for the treatment of tissue regeneration. | $250K | Pre-Seed | Jan 01, 2024 |  |
| SoyGreen | SoyGreen is an agtech company that offers emission reduction agbiologicals for sustainable agriculture. | $250K | Seed | Dec 01, 2023 |  |
| BioMetallum | BioMetallum is a biomining company that designs and develops solutions for extracting lithium and other metals. | $160K | Pre-Seed | Oct 11, 2023 |  |
| Inmet | Inmet S.A. is a biotechnological company that specializes in optimizing microorganisms for the bio-transformation of agro-industrial residues into high-value compounds. The company focuses on developing environmentally friendly technologies to convert waste into valuable products. Inmet S.A. employs a multidisciplinary approach in synthetic biologyto design and genetically optimize microorganisms for various industrial applications. | $500K | Pre-Seed | Oct 06, 2023 |  |
| Trebe Biotech | Trebe Biotech offers an innovative, high-throughput platform for the production of high-quality and complex recombinant proteins. | $500K | Pre-Seed | Oct 01, 2023 |  |
| Mycorium Biotech | Mycorium Biotech is upcycling waste into bioleather. We are the only startup in the world efficiently managing waste for the production of this biodegradable material.The fashion industry is in the midst of a sustainability crisis; it's the second most polluting on the planet, and it demands abandoning plastics. In line with SDG 12, we aimto promote responsible production and consumption through science.info@mycoriumbiotech.com | $350K | Pre-Seed | May 10, 2023 |  |

10 of 23 investments shown.

## Co-investors
- [Bioceres Crop Solutions](https://shizune.co/investors/profile/bioceres-crop-solutions) — VC Fund, 1 deal together
- [Brinc](https://shizune.co/investors/profile/brinc-io) — VC Fund, 1 deal together
- [Cites](https://shizune.co/investors/profile/cites-startups-2014) — VC Fund, 1 deal together
- [SOSV SF & NY (Fka IndieBio)](https://shizune.co/investors/profile/synbio-axlr8r) — VC Fund, 1 deal together
- [Time Partners Limited](https://shizune.co/investors/profile/time-partners-limited) — VC Fund, 1 deal together
- [Zentynel Frontier Investments](https://shizune.co/investors/profile/zentynel-frontier-investments) — VC Fund, 1 deal together

## Similar investors

### Similar industry
- [SOSV](https://shizune.co/investors/profile/sosv) — VC Fund
- [ARCH Venture Partners](https://shizune.co/investors/profile/arch-venture-partners) — VC Fund
- [OrbiMed](https://shizune.co/investors/profile/orbimed-advisors) — VC Fund

### Similar stage
- [Antler](https://shizune.co/investors/profile/antler-be9c) — VC Fund
- [Right Side Capital Management](https://shizune.co/investors/profile/right-side-capital-management) — VC Fund
- [Everywhere Ventures](https://shizune.co/investors/profile/everywhere-ventures) — VC Fund

### Similar country
- [Newtopia VC](https://shizune.co/investors/profile/newtopia-vc) — VC Fund
- [NXTP Ventures](https://shizune.co/investors/profile/nxtp-ventures) — VC Fund
- [Alaya Capital](https://shizune.co/investors/profile/alaya-capital) — VC Fund

## Featured in investor lists
- [Biotechnology Investors in LATAM](https://shizune.co/investors/biotechnology-investors-latam)
- [Biotechnology VC Funds in LATAM](https://shizune.co/investors/biotechnology-vc-funds-latam)
- [Biotech VC Funds in LATAM](https://shizune.co/investors/biotech-vc-funds-latam)
- [All Investors in Argentina](https://shizune.co/investors/investors-argentina)
- [All VC Funds in Argentina](https://shizune.co/investors/vc-funds-argentina)
- [Biotechnology Investors in Argentina](https://shizune.co/investors/biotechnology-investors-argentina)

## FAQ

### What does SF500 invest in?

SF500 invests primarily in Medical, Biopharma and Biotechnology startups, most often at Pre-Seed stage. Most of the 23 investments tracked by Shizune back companies in Argentina. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is SF500's check size?

SF500 typically joins rounds of $250k–$500k at Pre-Seed. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds SF500 participates in.

### When did SF500 last invest?

The most recent investment recorded for SF500 closed in Nov 2024. Shizune tracks 23 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

# About Shizune
Shizune.co is an investor database. Core features:
- 48,091 startup investors (angels, VCs, accelerators, and others)
- Email, phone, LinkedIn (for intros), socials, and other contact data
- Updated daily from public funding news
- CSV and Excel export

The User can access the full database FOR FREE after signing up: shizune.co