# Santo Holding

> Santo Holding is a VC fund in Zürich backing Biotechnology, Energy and Medical. See 6 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Zürich, Switzerland
- Total investments: 6
- Last investment: Mar 2019
- Lead investor: 50%
- Last updated: Aug 2026
- Website: http://santoholding.ch

Santo Holding is a Zurich-based investment firm funding biotechnology, pharmaceutical, life sciences, and healthcare companies.

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Biotechnology | 2 | 33% |
| Energy | 1 | 17% |
| Medical | 1 | 17% |
| CleanTech | 1 | 17% |
| GreenTech | 1 | 17% |

11 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Funding Round | 2 | 33% |
| Series B | 1 | 17% |
| Series C | 1 | 17% |
| Series D | 1 | 17% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| Germany | 2 | 33% |
| Austria | 1 | 17% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Efficient Energy | Efficient Energy GmbH is an innovative manufacturer and system supplier of environmentally friendly refrigeration technology, based in Feldkirchen near Munich, Germany. The company developed the Bluezero-technology, which uses water as a refrigerant and and thereby entirely avoids fluorinated refrigerants (HFCs). Efficient Energy helps itscustomers overcome the increasing regulatory challenges of refrigeration technology, and offers them long-term, sustainable solutions with its eChiller model range. The eChiller chilled water units are ideally suited for process cooling, machine cooling and the cooling of technical equipment and data centres and provide cooling capacities from 35 kW to 120 kW, depending on the model. With its outstanding cost efficiency and low CO2 footprint, companies benefit on many fronts. The pioneering technology has also been noticed by politics and the media, and has received multiple awards for the eChiller. These include among others the European Business Award for the Environment 2018/2019 from the European Comission and the Red Herring Europe Top 100 in 2020. | $8M |  | Mar 13, 2019 |  |
| Efficient Energy | Efficient Energy GmbH is an innovative manufacturer and system supplier of environmentally friendly refrigeration technology, based in Feldkirchen near Munich, Germany. The company developed the Bluezero-technology, which uses water as a refrigerant and and thereby entirely avoids fluorinated refrigerants (HFCs). Efficient Energy helps itscustomers overcome the increasing regulatory challenges of refrigeration technology, and offers them long-term, sustainable solutions with its eChiller model range. The eChiller chilled water units are ideally suited for process cooling, machine cooling and the cooling of technical equipment and data centres and provide cooling capacities from 35 kW to 120 kW, depending on the model. With its outstanding cost efficiency and low CO2 footprint, companies benefit on many fronts. The pioneering technology has also been noticed by politics and the media, and has received multiple awards for the eChiller. These include among others the European Business Award for the Environment 2018/2019 from the European Comission and the Red Herring Europe Top 100 in 2020. | $7.4M |  | Jun 28, 2018 |  |
| AFFiRiS | AFFiRiS AG, a Vienna, Austria-based developer of tailor-made peptide vaccines for Alzheimer's disease, Atherosclerosis, Parkinson's disease, hypertension and several other conditions. | $10M |  | Jun 28, 2016 |  |
| SuppreMol | SuppreMol is a privately held biotechnology company that pioneers a novel approach for the treatment of autoimmune diseases which could lead to the cure of these disorders instead of merely treating their symptoms. | $10.4M | Series D | May 21, 2013 |  |
| SuppreMol | SuppreMol is a privately held biotechnology company that pioneers a novel approach for the treatment of autoimmune diseases which could lead to the cure of these disorders instead of merely treating their symptoms. | $17M | Series C | Dec 17, 2010 |  |
| SuppreMol | SuppreMol is a privately held biotechnology company that pioneers a novel approach for the treatment of autoimmune diseases which could lead to the cure of these disorders instead of merely treating their symptoms. | $17.2M | Series B | Jul 15, 2008 |  |

6 of 6 investments shown.

## Co-investors
- [MIG Capital](https://shizune.co/investors/profile/mig-ag) — VC Fund, 6 deals together
- [BioMedPartners](https://shizune.co/investors/profile/biomedpartners) — VC Fund, 3 deals together
- [Bayern Kapital](https://shizune.co/investors/profile/bayern-kapital) — VC Fund, 2 deals together
- [FCP Biotech Holding](https://shizune.co/investors/profile/fcp-biotech-holding) — VC Fund, 2 deals together
- [KfW](https://shizune.co/investors/profile/kfw) — VC Fund, 2 deals together
- [Arax Capital Partners](https://shizune.co/investors/profile/arax-capital-partners) — VC Fund, 1 deal together

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## Featured in investor lists
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## FAQ

### What does Santo Holding invest in?

Santo Holding invests primarily in Biotechnology, Energy and Medical startups, most often at Funding Round and Series B stage. Most of the 6 investments tracked by Shizune back companies in Germany. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### When did Santo Holding last invest?

The most recent investment recorded for Santo Holding closed in Mar 2019. Shizune tracks 6 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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