# Sam Palmisano

> Sam Palmisano is a Series A investor backing Artificial Intelligence. See 9 investments, round sizes, portfolio and contact details. Updated Aug 2026.

- Type: Angel Investor
- Location: Southport, United States
- Total investments: 9
- Last investment: May 2025
- Lead investor: 0%
- Last updated: Aug 2026

Sam Palmisano is a Series A investor in Southport focused on Artificial Intelligence and Machine Learning. Palmisano was promoted to CEO in March 2002 and named chairman effective January 1, 2003, succeeding the retiring Louis V. Gerstner, Jr. after the Dot-com bubble bust. While his predecessor had saved the company from bankruptcy by downsizing the work force and cutting costs, and then leading IBM's resurgence with systems integration andservices consulting (such as e-commerce), Palmisano's goal was to reestablish IBM as a standard-setting company. He was influenced by the Watsons, the company founders who "always defined I.B.M. as a company that did more than sell computers; they believed that it had an important role to play in solving societal challenges

## Contacts

5 contacts available for Sam Palmisano: work email, personal email, work phone, personal phone and socials. Sign up free to unlock them: https://app.shizune.co/sign-up/investor-profiles/find-email/sam-palmisano?utm_source=investor_profile

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Artificial Intelligence | 6 | 67% |
| Machine Learning | 5 | 56% |
| Health Care | 2 | 22% |
| Mobile | 1 | 11% |
| Banking | 1 | 11% |

25 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Series A | 3 | 33% |
| Seed | 2 | 22% |
| Series B | 1 | 11% |
| Series D | 1 | 11% |
| Funding Round | 1 | 11% |

6 stages tracked in total.

## Investments

| Company | Description | Round size | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Catena Labs | Catena Labs incubate independent products spanning identity, communications, AI, and commerce. The company's mission is to empower people with agency, safety, value, and joy online. | $18M | Seed | May 20, 2025 | https://catena.xyz/ |
| Somewear Labs | Somewear is a satellite communications solution designed for the increasingly digital world. Somewear is building a satellite-powered platform to keep people safe. Somewear gives any remote operative a reliable line to safety and keeps organizations compliant at a fraction of the traditional cost with a combination of compact satellite hotspots andsoftware designed for low-bandwidth applications.It was founded in 2017 and is based in San Francisco, California. | $13.7M | Series A | Sep 22, 2022 | https://www.somewearlabs.com/ |
| Biocogniv | More than a decade since the HITECH Act established a timeline for EHR adoption, US hospitals today find themselves generating more clinical and administrative data on any given day than previously thought possible. Yet clinical operations are still based on subjective decision-making and traditional processes that ignore not only the raw data, butalso the valuable efficiency improvements that can be automatically derived from them.Biocogniv picks up where the EHR transformation left off and introduces real-time intelligence on top of this vast backdrop of data, to improve the quality, cost, and ultimately access to care in US health systems. | $6M | Seed | Mar 16, 2022 | https://biocogniv.com/ |
| Pryon | Pryon is an artificial intelligence company focused on enterprise knowledge management. Its natural language processing platform transforms unstructured data into experiences that increase productivity with unmatched accuracy and speed. Pryon’s automated machine learning engines deliver rapid time to value by enriching existing content. Thisno-code approach prevents operational disruption and allows organizations to quickly maximize the business value trapped within their information assets. Pryon was founded by Igor Jablokov, whose previous company defined the state of the art for AI assistants and was acquired by Amazon to form the basis for Alexa. | $12M |  | Nov 24, 2021 | https://pryon.com |
| Pryon | Pryon is an artificial intelligence company focused on enterprise knowledge management. Its natural language processing platform transforms unstructured data into experiences that increase productivity with unmatched accuracy and speed. Pryon’s automated machine learning engines deliver rapid time to value by enriching existing content. Thisno-code approach prevents operational disruption and allows organizations to quickly maximize the business value trapped within their information assets. Pryon was founded by Igor Jablokov, whose previous company defined the state of the art for AI assistants and was acquired by Amazon to form the basis for Alexa. | $12M | Venture - Series Unknown | Sep 27, 2021 | https://pryon.com |
| ClosedLoop | ClosedLoop is healthcare's data science platform. We make it easy for healthcare organizations to use AI to improve outcomes and reduce costs. Purpose-built for healthcare, ClosedLoop combines an intuitive end-to-end machine learning platform with a comprehensive library of healthcare-specific features and model templates. Customers useClosedLoop's Explainable AI to drive clinical excellence, operational efficiency, value-based contracts, and enhanced revenue. Winner of the CMS AI Health Outcomes Challenge and named Best in KLAS for Healthcare AI: Data Science Solutions 2022 and 2023, ClosedLoop is headquartered in Austin, Texas. | $34M | Series B | Aug 17, 2021 | http://closedloop.ai |
| LitLingo | LitLingo reduces a company's risk and improves compliance by providing patented AI-powered monitoring, prevention, and training solutions in real-time. We allow customers to target known risks, identify blind spots, and maximize the productivity of their compliance team. LitLingo is the best in the world at identifying potentially harmfulantitrust, anti-bribery & anti-corruption content in digital communications. We improve audits and investigations, replacing keyword search with machine learning and language models, reviewing 100% of desired communications and identifying the highest risk messages. | $7.5M | Series A | Jul 07, 2021 | https://www.litlingo.com/ |
| Craft.co | Craft is a machine-learning powered data and analytics platform building the “Source of Truth” on companies and mapping the global economy. The company organizes financial, operating and human capital data from thousands of sources to provide comprehensive, up-to-date sector and company profiles, ranging from early-stage to the largest companies inthe world, with analytics and tools such as signal alerts, trends and benchmarking. | $10M | Series A | Aug 21, 2020 | http://www.craft.co |
| Circle | Circle is a financial technology company that develops and manages digital currencies and blockchain-based financial infrastructure. It issues USD Coin (USDC) and Euro Coin (EURC), both fully backed stablecoins designed for global payments and digital transactions. Circle's platform supports businesses in integrating stablecoins into theiroperations, including cross-border payments and financial applications. Through the Circle Payments Network, it enables real-time settlement for financial institutions using USDC and EURC. | $60M | Series D | May 13, 2016 | https://www.circle.com |

9 of 9 investments shown.

## Co-investors
- [Breyer Capital](https://shizune.co/investors/profile/breyer-capital) — VC Fund, 8 deals together
- [Greycroft](https://shizune.co/investors/profile/greycroft) — VC Fund, 5 deals together
- [High Alpha](https://shizune.co/investors/profile/high-alpha-llc) — VC Fund, 4 deals together
- [Gaingels](https://shizune.co/investors/profile/gaing) — VC Fund, 3 deals together
- [Good Growth Capital](https://shizune.co/investors/profile/good-growth-capital) — VC Fund, 3 deals together
- [Revolution’s Rise of the Rest Seed Fund](https://shizune.co/investors/profile/rise-of-the-rest) — VC Fund, 3 deals together

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## FAQ

### What does Sam Palmisano invest in?

Sam Palmisano invests primarily in Artificial Intelligence, Machine Learning and Health Care startups, most often at Series A and Seed stage. Most of the 9 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### How do I contact Sam Palmisano?

For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

### When did Sam Palmisano last invest?

The most recent investment recorded for Sam Palmisano closed in May 2025. Shizune tracks 9 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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