# Missouri Technology Corporation

> Missouri Technology Corporation is a VC fund backing Health Care and Biotechnology. See 127 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Jefferson City, United States
- Total investments: 127
- Last investment: Mar 2026
- Lead investor: 44%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/missouri-technology-corporation
- X (Twitter): http://twitter.com/MoTechCorp
- Website: http://www.missouritechnology.com

Missouri Technology Corporation is an American venture capital firm that promotes entrepreneurship and the growth of high-tech companies. Promoting entrepreneurship and fostering the growth of emerging, high-tech companies in Missouri

## Round sizes

| Stage | Round size |
| --- | --- |
| Seed | $100k–$1.8M |
| Grant | $50k–$9.5M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 32 | 25% |
| Biotechnology | 30 | 24% |
| Software | 20 | 16% |
| Information Technology | 12 | 9% |
| Mobile | 9 | 7% |

152 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 49 | 39% |
| Grant | 23 | 18% |
| Funding Round | 11 | 9% |
| Series A | 10 | 8% |
| Pre-Seed | 4 | 3% |

9 stages tracked in total.

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Endeavor Heartland | Endeavor Heartland is a nonprofit organization that provides entrepreneur support and economic development services. | $250K | Grant | Mar 27, 2026 |  |
| Plastomics | Plastomics is a biotechnology startup that focuses in developing the next generation of crops by using chloroplast genetic engineering. Its technology platform is applicable to different crops and traits. Plastomics provides solutions for the many current industry challenges.The company was founded in 2016 and headquartered in St. Louis,Missouri. | $5.8M | Series B | Oct 15, 2025 |  |
| Aegis Digital Health | Aegis Digital Health delivers solutions in virtual care and remote patient monitoring to healthcare providers. | $1M | Seed | Sep 11, 2025 |  |
| OpsCompanion | Your team is shipping with AI. Agents are writing code, changing your infrastructure, pushing to production. Nobody tracks what those agents did last week, or why a similar change broke production three months ago. OpsCompanion does. It maps how your systems behave over time, so when an AI coding tool is about to repeat a mistake or cross aboundary your team set, it catches the problem before your customers do. Every agent action, every incident, every fix builds operational memory specific to your environment. That memory feeds back into agent sessions, giving your AI tools the guardrails and context they need to make better decisions automatically.We built OpsCompanion for mid-market engineering teams that need AI agent governance, monitoring, and audit trails without hiring a dedicated SRE or building internal tooling from scratch. Connect your tools and go live in under two weeks.You started building because you had something worth making. OpsCompanion makes sure it stays that way. |  | Pre-Seed | Sep 05, 2025 |  |
| Solis Agrosciences | Solis Agrosciences provides R&D crop development services to Agtech companies. Founded in 2021, Solis Agrosciences is a plant science services company on a mission to accelerate the pace of scientific discovery and commercialization. | $1.3M | Series A | Jul 10, 2025 |  |
| Aferna Bio | Aferna Bio is a biotechnology research company. | $500K | Seed | Feb 07, 2025 |  |
| Agragene | Agragene operates as a sustainable agricultural technology company developing novel biological crop pest protection products. Agragene is advancing Precision-Guided Sterile Insect Technology (pgSIT), an eco-friendly CRISPR-based approach to engineer sterile male crop pests that mate with wild female crop pests.The company uses advanced genomeengineering to create and commercialize sustainable products that are applicable to thousands of insect pests worldwide, thereby enabling farmers to enhance the quality and productivity of economically important foods and crops.Agragene was established in 2017 and is based in San Diego, CA. |  | Venture - Series Unknown | Aug 06, 2024 |  |
| Edison Agrosciences | Edison Agrosciences is an agricultural biotechnology company dedicated to developing and commercializing innovative solutions for the production of plant-based industrial materials, with a primary focus on the development of alternative rubber crops. They are engineering yield improvements and the novel production of industrial materials insuitable plant systems. Edison has an emerging IP portfolio covering multiple technical strategies and they are developing strategic partnerships to mitigate the risk of pilot scale crop and product validation. Edison’s strong leadership team has a track record of success in industry. | $600K | Seed | Jul 25, 2024 |  |
| Maximum Fidelity Surgical Simulations | Maximum Fidelity Surgical Simulations manufactures medical, surgical, ophthalmic, and veterinary instruments and apparatus. It prepares medical personnel for military trauma, test biomedical devices, and provides hyper-realistic medical education using a lifelike patient and without endangering human life. | $2.3M | Seed | Jul 09, 2024 |  |
| Maximum Fidelity Surgical Simulations | Maximum Fidelity Surgical Simulations manufactures medical, surgical, ophthalmic, and veterinary instruments and apparatus. It prepares medical personnel for military trauma, test biomedical devices, and provides hyper-realistic medical education using a lifelike patient and without endangering human life. | $2.3M | Seed | Jul 09, 2024 |  |

10 of 127 investments shown.

## Co-investors
- [BioGenerator](https://shizune.co/investors/profile/biogenerator) — VC Fund, 21 deals together
- [St. Louis Arch Angels](https://shizune.co/investors/profile/st-louis-arch-angels) — VC Fund, 16 deals together
- [Cultivation Capital](https://shizune.co/investors/profile/cultivation-capital) — VC Fund, 15 deals together
- [iSelect Fund](https://shizune.co/investors/profile/iselectfund) — VC Fund, 7 deals together
- [BioGenerator Ventures](https://shizune.co/investors/profile/biogenerator-ventures) — VC Fund, 6 deals together
- [The Yield Lab](https://shizune.co/investors/profile/the-yield-lab) — VC Fund, 6 deals together

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## FAQ

### What does Missouri Technology Corporation invest in?

Missouri Technology Corporation invests primarily in Health Care, Biotechnology and Software startups, most often at Seed and Grant stage. Most of the 127 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Missouri Technology Corporation's check size?

Missouri Technology Corporation typically joins rounds of $100k–$1.8M at Seed and $50k–$9.5M at Grant. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Missouri Technology Corporation participates in.

### When did Missouri Technology Corporation last invest?

The most recent investment recorded for Missouri Technology Corporation closed in Mar 2026. Shizune tracks 127 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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