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Mike Spadafore, Angel Investor at The Blue Venture Fund

Mike Spadafore

Angel Investor @ The Blue Venture Fund

Chicago, United States

Mike Spadafore is an Analyst with the BlueCross BlueShield Venture Funds at Sandbox Industries. Prior to joining Sandbox, Mike was an Experienced Associate with PwC and an Analyst with Diamond Management and Technology Consultants in their Healthcare Strategy practices. During Mike’s management consulting career, he led projects and work tracksfor a number of projects in IT strategy, mobile strategy, and information strategy. Mike holds a BBA from the University of Michigan Ross School of Business.

Total investments:
18
Last investment:
Lead investor:
50%

Last updated:

Industries Mike Spadafore invests in

Health CareInformation TechnologyWellnessMobileFinTech

Stages Mike Spadafore invests in

Series ASeries BSeries CSeries DSeries E

Countries Mike Spadafore invests in

United States

Contacts

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Investment Focus

Industry

  • Health Care 5 (28%)
  • Information Technology 3 (17%)
  • Wellness 2 (11%)
  • Mobile 1 (6%)
  • FinTech 1 (6%)
See all 11 industries →

Stage

  • Series A 3 (17%)
  • Series B 3 (17%)
  • Series C 1 (6%)
  • Series D 1 (6%)
  • Series E 1 (6%)
See all 6 stages →

Investments

CompanyDescriptionRoundLinks
Arbital Health is a healthcare company that offers a third-party adjudication utility to help bolster outcomes-based healthcare contracts. $31M / Series B / Jul 29, 2025
Autonomize AI is a human-centric AI platform that learns from multi-structured clinical and biomedical data and pairs it with human context to aid decision-making and data discovery. They extract contextual information from multi-structured healthcare data, enrich with human know-how, and aid decision-making and data discovery. $28M / Series A / Jun 12, 2025
Atropos Health rapidly provides personalized real-world evidence for any clinical decision $33M / Series B / May 23, 2024
First Dollar is a healthcare savings platform with a focus on HSAs (health savings accounts) that targets millennials and Gen Z. $14M / Series A / Jan 27, 2022
axialHealthcare connects patients, providers, and health plans with an end-to-end platform that covers the entire substance use spectrum. Our high-tech, high-touch approach mends fractured ecosystems, identifies at-risk patients, and provides timely, interactive tools for clinical decision-making. For patients with substance use disorder, we offera clear path with continuity of care. $75M / Series D / Sep 28, 2021
Prove is a smartphone-based identity verification startup that specializes in providing phone-centric and API marketplace solutions. Its phone-centric solutions enable its customers to acquire new consumers and engage with their existing consumers by removing friction while bolstering security and enhancing consumer privacy and consumer choice. $100M / Series H / Jun 18, 2020
axialHealthcare connects patients, providers, and health plans with an end-to-end platform that covers the entire substance use spectrum. Our high-tech, high-touch approach mends fractured ecosystems, identifies at-risk patients, and provides timely, interactive tools for clinical decision-making. For patients with substance use disorder, we offera clear path with continuity of care. $15M / Series C / Feb 27, 2020
Prove is a smartphone-based identity verification startup that specializes in providing phone-centric and API marketplace solutions. Its phone-centric solutions enable its customers to acquire new consumers and engage with their existing consumers by removing friction while bolstering security and enhancing consumer privacy and consumer choice. $23.5M / Series E / Jan 05, 2017
axialHealthcare connects patients, providers, and health plans with an end-to-end platform that covers the entire substance use spectrum. Our high-tech, high-touch approach mends fractured ecosystems, identifies at-risk patients, and provides timely, interactive tools for clinical decision-making. For patients with substance use disorder, we offera clear path with continuity of care. $16.5M / Series B / Oct 12, 2016
axialHealthcare connects patients, providers, and health plans with an end-to-end platform that covers the entire substance use spectrum. Our high-tech, high-touch approach mends fractured ecosystems, identifies at-risk patients, and provides timely, interactive tools for clinical decision-making. For patients with substance use disorder, we offera clear path with continuity of care. $8M / Series A / Jul 14, 2015
See all 18 investments →

Co-Investors

The Blue Venture Fund

About The Blue Venture Fund

VC Fund · Chicago, United States

The Blue Venture Fund is a strategic investment vehicle that aims to foster innovation within the healthcare system. The Blue Venture Fund invests in emerging healthcare companies that have the potential to improve the quality of care, enhance patient experience, and reduce costs. It seeks to support companies that align with the needs andpriorities of Blue Cross Blue Shield (BCBS) member companies and their policyholders.

The Blue Venture Fund Contacts

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John Banta
John Banta President and Managing Director

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FAQ

What does Mike Spadafore invest in?

Mike Spadafore invests primarily in Health Care, Information Technology and Wellness startups, most often at Series A and Series B stage. Most of the 18 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Mike Spadafore?

Public channels for Mike Spadafore include LinkedIn and X (Twitter). For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Mike Spadafore last invest?

The most recent investment recorded for Mike Spadafore closed in Jul 2025. Shizune tracks 18 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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