# Lena Krzyzak

> Lena Krzyzak is a seed investor at HTGF (High-Tech Gruenderfonds) backing Biotechnology. See 3 investments, check sizes, portfolio. Updated Aug 2026.

- Type: Angel Investor
- Fund: [HTGF (High-Tech Gruenderfonds)](https://shizune.co/investors/profile/high-tech-gr%C3%BCnderfonds)
- Location: Frankfurt, Germany
- Total investments: 3
- Last investment: Apr 2026
- Lead investor: 33%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/in/lena-krzyzak-419159b4/

Lena Krzyzak is a seed investor at HTGF (High-Tech Gruenderfonds) in Frankfurt focused on Biotechnology and Commercial. Lena Krzyzak - Principal @ HTGF (High-Tech Gruenderfonds)

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Biotechnology | 2 | 67% |
| Commercial | 1 | 33% |
| Health Care | 1 | 33% |
| Life Science | 1 | 33% |
| Therapeutics | 1 | 33% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| Germany | 1 | 33% |
| United States | 1 | 33% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Tacalyx | Tacalyx develops therapeutics targeting cancer-specific carbohydrate antigens on the surface of metastatic malignant tumors where no satisfactory treatments exist.The name Tacalyx is derived from TACA (Tumor Associated Carbohydrate Antigen) and ‘lyx’ from the term Glycocalyx, the glycan-containing layer covering cells. Cancer cells differ fromnormal cells by displaying aberrant carbohydrate structures on their surfaces promoting metastasis, angiogenesis or suppression of the immune system. TACAs result from the aberrant glycosylation that is seen with transformation to a tumor cell and represent attractive targets for cancer treatment since they are displayed with high cancer specificity and enhance tumor virulence via the mentioned diverse mechanisms. | $12.9M | Seed | Apr 29, 2026 |  |
| Tacalyx | Tacalyx develops therapeutics targeting cancer-specific carbohydrate antigens on the surface of metastatic malignant tumors where no satisfactory treatments exist.The name Tacalyx is derived from TACA (Tumor Associated Carbohydrate Antigen) and ‘lyx’ from the term Glycocalyx, the glycan-containing layer covering cells. Cancer cells differ fromnormal cells by displaying aberrant carbohydrate structures on their surfaces promoting metastasis, angiogenesis or suppression of the immune system. TACAs result from the aberrant glycosylation that is seen with transformation to a tumor cell and represent attractive targets for cancer treatment since they are displayed with high cancer specificity and enhance tumor virulence via the mentioned diverse mechanisms. | $7.4M | Seed | Sep 25, 2019 |  |
| NAVAN Technologies | NAVAN Technologies, Inc., (NAVAN) is a pre-clinical stage biotechnology company developing and commercializing its proprietary NanoStraw platform technology, which establishes a direct, physical connection into cells to overcome a huge challenge faced by researchers globally: delivering material into hard-to-transfect-cells in an efficient yetgentle and non-perturbative manne |  | Seed | Apr 25, 2019 |  |

3 of 3 investments shown.

## Co-investors
- [Boehringer Ingelheim Venture Fund](https://shizune.co/investors/profile/boehringer-ingelheim-venture-fund) — VC Fund, 2 deals together
- [Creathor Ventures](https://shizune.co/investors/profile/creathor-venture-management) — VC Fund, 2 deals together
- [Kurma Partners](https://shizune.co/investors/profile/kurma-life-science-partners) — VC Fund, 2 deals together
- [Amgen Ventures](https://shizune.co/investors/profile/amgen-ventures) — VC Fund, 1 deal together
- [coparion](https://shizune.co/investors/profile/coparion) — VC Fund, 1 deal together
- [Eurazeo](https://shizune.co/investors/profile/eurazeo-com) — VC Fund, 1 deal together

## About HTGF (High-Tech Gruenderfonds)

VC Fund · Bonn, Germany

High-Tech Grunderfonds finances startups with growth potential. Its team of investment managers supports young companies with expertise, entrepreneurial spirit, and passion. The company focuses in the fields of digital tech, industrial tech, life sciences, chemistry, and related business areas. It also focuses on financial services in varioussectors.

5 contacts available at HTGF (High-Tech Gruenderfonds).

| Name | Title | Profile |
| --- | --- | --- |
| Alexander Hölz | Investment Controller | https://shizune.co/investors/profile/alexander-hlz |
| Cornelia Klug | Marketing & Communications | https://shizune.co/investors/profile/cornelia-klug |
| Irina Gerlach | Head of Office | https://shizune.co/investors/profile/irina-gerlach |
| Kristin Müller | Investment Manager | https://shizune.co/investors/profile/kristin-muller |
| Lena Krzyzak | Principal | https://shizune.co/investors/profile/lena-krzyzak |

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## FAQ

### What does Lena Krzyzak invest in?

Lena Krzyzak invests primarily in Biotechnology, Commercial and Health Care startups, most often at Seed stage. Most of the 3 investments tracked by Shizune back companies in Germany. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### When did Lena Krzyzak last invest?

The most recent investment recorded for Lena Krzyzak closed in Apr 2026. Shizune tracks 3 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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