# Hawktail Management

> Hawktail Management is a VC fund in Palo Alto backing Biotechnology and Artificial Intelligence. See 29 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Palo Alto, United States
- Total investments: 29
- Last investment: Feb 2026
- Lead investor: 0%
- Last fund: Mar 2021
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/hawktailvc/
- Website: https://hawktail.com/

Hawktail Management is a VC fund in Palo Alto focused on Biotechnology and Artificial Intelligence. Hawktail Management operates as an investment firm.

## Round sizes

| Stage | Round size |
| --- | --- |
| Seed | $4.6M–$15M |
| Pre-Seed | $2.7M–$4M |
| Series A | $20M–$78M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Biotechnology | 11 | 38% |
| Artificial Intelligence | 7 | 24% |
| Software | 6 | 21% |
| Life Science | 4 | 14% |
| Information Technology | 4 | 14% |

49 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Seed | 17 | 59% |
| Pre-Seed | 6 | 21% |
| Series A | 3 | 10% |
| Series B | 1 | 3% |
| Venture - Series Unknown | 1 | 3% |

### Country

| Country | Investments | Share |
| --- | --- | --- |
| United States | 19 | 66% |
| Sweden | 2 | 7% |
| United Kingdom | 2 | 7% |
| Canada | 1 | 3% |
| Australia | 1 | 3% |

6 countries tracked in total.

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| LuminosAI | Luminos AI provides software for legal and governance teams to assess and manage AI risk. The platform supports compliance testing, evaluation workflows, and automated reporting across classical, generative, and agentic AI systems. | $7.8M | Venture - Series Unknown | Feb 24, 2026 |  |
| Transformer Lab | Open source platform for training large language models |  | Pre-Seed | Feb 02, 2026 |  |
| Biologica | Biologica provides supplements designed to support women through the reproductive years, perimenopause, and post menopause stages. | $7M | Seed | Dec 09, 2025 |  |
| Vulcan | Vulcan builds AI tools that map U.S. laws and regulations, helping users draft, review, and stay compliant with legal documents. | $10.9M | Seed | Oct 09, 2025 |  |
| Atmanity | Brining AI to life. | $4M | Pre-Seed | Jul 01, 2025 |  |
| Terrain Bio | Terrain BioSciences is in the field of RNA-based therapeutics and vaccine development. Leveraging advanced AI and proprietary manufacturing platforms, Terrain BioSciences addresses the challenges of designing, selecting, manufacturing, and delivering optimal RNA sequences. Terrain BioSciences collaborates with over a dozen biotech firms to enhancethe expression, durability, and manufacturability of RNA sequences, significantly accelerating their path to clinical application. With a focus on personalized cancer vaccines and other RNA-based modalities, Terrain BioSciences is at the forefront of the next generation of programmable medicines. | $9M | Seed | Feb 12, 2025 |  |
| ExpressionEdits | ExpressionEdits operates in the biotechnology industry, focusing on the redesign of synthetic DNA instructions. The company utilizes an AI-driven approach to redefine the status quo of protein expression. It is involved in building biology similar to nature. The team at ExpressionEdits includes scientists and engineers who are dedicated todeveloping new technologies. Proteins, a foundational pillar in healthcare and behind every major advancement in biotech and synthetic biology, are at the core of their work. | $13M | Seed | May 29, 2024 |  |
| Cache | Biomolecules are the next bits of the 21st century. So we're developing the first wet operating system for storing, accessing, and computing biomolecules at scale to make them widely accessible and useful. We're enabling the storage and access to the whole data universe—digital and biological—forever so that we don't have to deleteor dispose of anything ever again. |  | Seed | May 07, 2024 |  |
| OverT Bio | OverT Bio operates as a biotech company that provide cell therapy for cancers.. The company's cell therapies identify and develop novel genetic modifications that will help immune cells overcome barriers created by tumors and lead to effective and durable immunotherapies, helping the healthcare industry to identify and cure cancer. | $16M | Seed | May 06, 2024 |  |
| SKYE | SKYE is a renewable energy company intended for enterprise segment | $3.3M | Pre-Seed | Feb 27, 2024 |  |

10 of 29 investments shown.

## Co-investors
- [Liquid 2 Ventures](https://shizune.co/investors/profile/liquid2-ventures) — VC Fund, 6 deals together
- [SV Angel](https://shizune.co/investors/profile/sv-angel) — VC Fund, 6 deals together
- [Acequia Capital (AceCap)](https://shizune.co/investors/profile/acequia-capital) — VC Fund, 3 deals together
- [Lowercarbon Capital](https://shizune.co/investors/profile/lowercarbon-capital) — VC Fund, 3 deals together
- [Olive Capital](https://shizune.co/investors/profile/olive-capital-f743) — VC Fund, 3 deals together
- [Tencent](https://shizune.co/investors/profile/tencent) — VC Fund, 3 deals together

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## FAQ

### What does Hawktail Management invest in?

Hawktail Management invests primarily in Biotechnology, Artificial Intelligence and Software startups, most often at Seed and Pre-Seed stage. Most of the 29 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Hawktail Management's check size?

Hawktail Management typically joins rounds of $4.6M–$15M at Seed, $2.7M–$4M at Pre-Seed and $20M–$78M at Series A. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Hawktail Management participates in.

### When did Hawktail Management last invest?

The most recent investment recorded for Hawktail Management closed in Feb 2026. Shizune tracks 29 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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