# Flanders Innovation & Entrepreneurship (VLAIO)

> Flanders Innovation & Entrepreneurship (VLAIO) is a VC fund backing Artificial Intelligence. See 12 investments, check sizes, portfolio. Updated Aug 2026.

- Type: VC Fund
- Location: Brussels, Belgium
- Total investments: 12
- Last investment: Jun 2026
- Lead investor: 67%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/company/vlaio-be
- Website: https://www.vlaio.be/en

Flanders Innovation & Entrepreneurship (VLAIO) is a VC fund in Brussels focused on Artificial Intelligence and Biotechnology. Flanders Innovation & Entrepreneurship (VLAIO) focuses on the implementation of economic and enterprise policies. VLAIO provides financial support through grants to help local businesses grow, innovate, and transform, including subsidies for SMEs.

## Round sizes

| Stage | Round size |
| --- | --- |
| Grant | $58k–$2.2M |

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Artificial Intelligence | 4 | 33% |
| Biotechnology | 3 | 25% |
| Software | 2 | 17% |
| Health Care | 2 | 17% |
| Therapeutics | 2 | 17% |

37 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Grant | 9 | 75% |
| Seed | 1 | 8% |
| Pre-Seed | 1 | 8% |
| Debt Financing | 1 | 8% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| Zymofix | Zymofix facilitates sustainable and circular agriculture by developing creative, effective, and commercially feasible microbial products that reduce farmers' reliance on agrochemicals while maintaining high productivity. | $2.2M | Grant | Jun 24, 2026 |  |
| Astracite | Astracite designs next-generation, climate-positive graphite-silicon composite anode materials explicitly engineered for lithium-ion batteries. The business model addresses global supply chain and environmental vulnerabilities by transforming captured carbon dioxide emissions into high-performing battery components via an eco-friendly processpowered by green electricity. By structurally embedding silicon into a specialized carbon matrix, the company delivers a fivefold capacity boost over traditional synthetic graphite while maintaining an ultra-low manufacturing footprint. | $441.2K | Grant | Jun 16, 2026 |  |
| Orion Intelligence | Orion Intelligence provides AI voice operators purpose-built for alarm monitoring centers. Its flagship solution automates routine and high-volume calls—both inbound and outbound—while integrating directly with central station platforms such as Manitou and Stages (Bold Group), MAS (Honeywell), Horus (Azursoft) and others.By fitting into existingtelephony and operational workflows, Orion enables monitoring centers to scale efficiently without increasing headcount. The company operates globally, including through its U.S. entity, Orion Intelligence USA, Inc.Orion Intelligence is a fully bootstrapped company with no external investors and generates between €1.5M and €2.5M in annual recurring revenue (ARR). | $550K | Grant | May 19, 2026 |  |
| Vectis.ai | Vectis.ai is building the Hardware Creation Engine, a new software category that converts natural language specifications into certified, manufacturable electronics. Our platform pairs reinforcement learning and Bayesian optimisation with deterministic physics simulation and regulatory verification to eliminate the prototype-fail-redesign loop inPCB development. We deliver Zero-Iteration Hardware: from natural language to first-pass CE marking, backed by a compounding compliance dataset and regulatory constraint library. | $57.7K | Grant | Mar 20, 2026 |  |
| Vertical Compute | Vertical Compute offers chiplet-based technology that cuts data movement to achieve up to 80% energy savings. |  | Grant | Mar 04, 2026 |  |
| Confo Therapeutics | Confo Therapeutics is a drug discovery company building internal drug discovery programs on GPCRs addressing unmet medical need. Confo Therapeutics employs its proprietary CONFO technology to lock inherent unstable functional conformations of GPCRs as a superior starting point for drug discovery. CONFO body-stabilized active state conformations ofthese receptors disclose previously inaccessible structural features empowering the discovery of novel agonists for better therapeutic intervention. | $1.2M | Grant | Oct 08, 2025 |  |
| OnTracx | OnTracx combines wearable technology and intelligent load management software to support runners and professionals to avoid running injuries & return to run safely. |  | Grant | Sep 16, 2025 |  |
| Cashfeed | Automating e-invoicing | $1.5M | Pre-Seed | Jul 08, 2025 |  |
| Taglayer | Taglayer offers easy-to-use online personalisation software that enables websites to present the right content to the right visitor at the right time. They help companies to increase on-site conversion and revenue, by showing more relevant content to their customers. | $909.8K | Debt Financing | Apr 17, 2025 |  |
| ClimateCamp | ClimateCamp offers precise information on the supply chain's carbon emissions. | $3.8M | Seed | Mar 25, 2025 |  |

10 of 12 investments shown.

## Co-investors
- [PMV](https://shizune.co/investors/profile/pmv-eu) — VC Fund, 2 deals together
- [Bpifrance](https://shizune.co/investors/profile/bpifrance) — VC Fund, 1 deal together
- [Expon Capital](https://shizune.co/investors/profile/expon-capital) — VC Fund, 1 deal together
- [KBC](https://shizune.co/investors/profile/kbc) — VC Fund, 1 deal together
- [KBC Bank & Verzekering](https://shizune.co/investors/profile/kbc-bank-verzekering) — VC Fund, 1 deal together
- [Luxembourg Ministry of Economy](https://shizune.co/investors/profile/luxembourg-ministry-of-economy) — VC Fund, 1 deal together

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## FAQ

### What does Flanders Innovation & Entrepreneurship (VLAIO) invest in?

Flanders Innovation & Entrepreneurship (VLAIO) invests primarily in Artificial Intelligence, Biotechnology and Software startups, most often at Grant and Seed stage. Most of the 12 investments tracked by Shizune back companies in Belgium. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### What is Flanders Innovation & Entrepreneurship (VLAIO)'s check size?

Flanders Innovation & Entrepreneurship (VLAIO) typically joins rounds of $58k–$2.2M at Grant. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Flanders Innovation & Entrepreneurship (VLAIO) participates in.

### When did Flanders Innovation & Entrepreneurship (VLAIO) last invest?

The most recent investment recorded for Flanders Innovation & Entrepreneurship (VLAIO) closed in Jun 2026. Shizune tracks 12 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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