# Alyssa Jaffee

> Alyssa Jaffee is a Series A investor at 7wire Ventures (Chicago) backing Health Care and Wellness. See 11 investments, check sizes, portfolio. Updated Aug 2026.

- Type: Angel Investor
- Fund: [7wire Ventures](https://shizune.co/investors/profile/7wire-ventures)
- Location: Chicago, United States
- Total investments: 11
- Last investment: Aug 2024
- Lead investor: 27%
- Last updated: Aug 2026
- LinkedIn: https://www.linkedin.com/in/alyssa-jaffee-71095011/

Alyssa Jaffee is a Partner of 7wire Ventures. Alyssa joined PGVC in August 2016 where she focuses on enterprise software and digital health. Most recently, she was the co-founder of TransparentC, 2016 NVC winning company focused on helping people make more data-driven career decisions with the first platform, www.transparentmba.com.Alyssa’s priorexperience in venture capital includes time at Hyde Park Angels (HPA), one of the Midwest’s largest angel organizations, focusing on B2B SaaS, as well as Healthbox, an early stage healthcare innovation firm, supporting their accelerator program called the Studio.Prior to business school, Alyssa worked as the Senior Director of Performance Technologies for the Advisory Board Company. There, Alyssa was charged with expanding new business through the sales of healthcare technology platforms. With an extensive travel regimen, Alyssa met with hundreds of hospital executive teams to understand their strategic needs and recommend various solutions. She has copious amounts of experience in launching new products and thinking about go-to-market strategies.Alyssa holds a bachelor degree with honors in Marketing and Spanish from the University of Wisconsin-Madison and an M.B.A. from the University of Chicago – Booth School of Business.

## Investment focus

### Industry

| Industry | Investments | Share |
| --- | --- | --- |
| Health Care | 5 | 45% |
| Wellness | 3 | 27% |
| Medical | 2 | 18% |
| FinTech | 1 | 9% |
| Fitness | 1 | 9% |

17 industries tracked in total.

### Stage

| Stage | Investments | Share |
| --- | --- | --- |
| Series A | 5 | 45% |
| Series B | 2 | 18% |
| Seed | 1 | 9% |

## Investments

| Company | Description | Amount | Stage | Date | Website |
| --- | --- | --- | --- | --- | --- |
| PayZen | PayZen is a healthcare fintech startup that aims to tackle the growing patient payment responsibility problem. The mission-driven company together with its superior technology and a new approach enables patients to pay their out-of-pocket medical bills over time with convenience and transparency. While Medical Providers should be able to focus onproviding healthcare services rather than financial services. The company achieves better financial outcomes for both patients and providers through Smart Medical Payment Plans And Non-Recourse Patient Financing.Ariel Rosenthal, Itzik Cohen, and Tobias Mezger co-founded the company in San Francisco, California in 2019. | $32M | Series B | Aug 13, 2024 |  |
| Summer Health | Summer Health is the first step and ongoing tool for anyone navigating health concerns, offering timely text access to high-quality healthcare professionals who provide expert answers and reliable advice over text. | $11.7M | Series A | Apr 23, 2024 |  |
| Caraway | Caraway is a digital healthcare company for college women+ that provides integrated mental, reproductive and physical healthcare services. Built with students for students, Caraway arms women+ with the first personalized, equitable and digitally-accessible care solution that prioritizes their needs and concerns. With an unprecedented need formental health resources and new barriers and persistent inequities in women’s+ health, Caraway provides access to trusted, holistic, and compassionate healthcare so women+ can get the care they need when they need it. | $16.8M | Series A | Jun 20, 2023 |  |
| NOCD | NOCD is an online OCD therapy platform that helps people with OCD get better and then stay better. With NOCD, users can have face-to-face video therapy sessions with licensed therapists that specialize in OCD, as well as get 24/7 support between sessions from self-help tools and peer communities. | $34M | Series B | Jan 31, 2023 |  |
| PayZen | PayZen is a healthcare fintech startup that aims to tackle the growing patient payment responsibility problem. The mission-driven company together with its superior technology and a new approach enables patients to pay their out-of-pocket medical bills over time with convenience and transparency. While Medical Providers should be able to focus onproviding healthcare services rather than financial services. The company achieves better financial outcomes for both patients and providers through Smart Medical Payment Plans And Non-Recourse Patient Financing.Ariel Rosenthal, Itzik Cohen, and Tobias Mezger co-founded the company in San Francisco, California in 2019. | $20M | Series B | Nov 15, 2022 |  |
| Summer Health | Summer Health is the first step and ongoing tool for anyone navigating health concerns, offering timely text access to high-quality healthcare professionals who provide expert answers and reliable advice over text. | $7.5M | Seed | Jul 25, 2022 |  |
| Jasper Health | Jasper Health provides personalized support to patients living with cancer, regardless of income. It provides access to valuable tools and resources free of charge. It was founded in 2020 and is based in New York, New York. | $25M | Series A | Feb 01, 2022 |  |
| MedArrive | MedArrive is a startup that connects a workforce of EMS professionals to patients from their homes and within their existing health systems. It enables healthcare providers to seamlessly extend care services into the home, unlocking access to high-quality healthcare for more people at a fraction of the cost. The startup's platform allowsproviders and payors to bridge the virtual care gap by connecting physician-led telemedicine with hands-on care from EMS professionals. This unique approach means that patients can access trusted medical expertise from the comfort and safety of their homes without any interruption to the continuity of care, ultimately resulting in better patient outcomes, a better-utilized healthcare workforce, and significant cost savings for patients and providers alike.MedArrive was founded in 2020 and is headquartered in New York, USA. | $25M | Series A | Nov 17, 2021 |  |
| NOCD | NOCD is an online OCD therapy platform that helps people with OCD get better and then stay better. With NOCD, users can have face-to-face video therapy sessions with licensed therapists that specialize in OCD, as well as get 24/7 support between sessions from self-help tools and peer communities. | $33M | Series B | Sep 21, 2021 |  |
| NOCD | NOCD is an online OCD therapy platform that helps people with OCD get better and then stay better. With NOCD, users can have face-to-face video therapy sessions with licensed therapists that specialize in OCD, as well as get 24/7 support between sessions from self-help tools and peer communities. | $12M | Series A | Oct 08, 2020 |  |

10 of 11 investments shown.

## Co-investors
- [Chicago Ventures](https://shizune.co/investors/profile/chicago-ventures) — VC Fund, 4 deals together
- [Health Enterprise Partners](https://shizune.co/investors/profile/health-enterprise-partners) — VC Fund, 4 deals together
- [General Catalyst](https://shizune.co/investors/profile/general-catalyst-partners) — VC Fund, 3 deals together
- [BoxGroup](https://shizune.co/investors/profile/boxgroup) — VC Fund, 2 deals together
- [Eight Roads Ventures](https://shizune.co/investors/profile/eight-roads-ventures) — VC Fund, 2 deals together
- [F-Prime](https://shizune.co/investors/profile/f-prime-capital-partners) — VC Fund, 2 deals together

## About 7wire Ventures

VC Fund · Chicago, United States

7wire ventures focuses on investing in early and growth-stage companies focused on healthcare IT, digital healtcare and mobile health.

5 contacts available at 7wire Ventures.

| Name | Title | Profile |
| --- | --- | --- |
| Lee Shapiro | Co-Founder & Managing Partner | https://shizune.co/investors/profile/lee-shapiro |
| Robert Garber | Managing Partner | https://shizune.co/investors/profile/robert-garber |
| Alyssa Jaffee | Partner | https://shizune.co/investors/profile/alyssa-jaffee |
| David Schonthal | Operating Partner | https://shizune.co/investors/profile/david-schonthal |
| Glen Tullman | Co-Founder & Managing Partner | https://shizune.co/investors/profile/glen-tullman |

## Similar investors

### Similar stage
- [Antler](https://shizune.co/investors/profile/antler-be9c) — VC Fund
- [Alumni Ventures](https://shizune.co/investors/profile/alumni-ventures-group) — VC Fund
- [General Catalyst](https://shizune.co/investors/profile/general-catalyst-partners) — VC Fund

## FAQ

### What does Alyssa Jaffee invest in?

Alyssa Jaffee invests primarily in Health Care, Wellness and Medical startups, most often at Series A and Series B stage. Most of the 11 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

### When did Alyssa Jaffee last invest?

The most recent investment recorded for Alyssa Jaffee closed in Aug 2024. Shizune tracks 11 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

### Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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