# Top 50 Machine Learning Startup Investors in United States in June 2026 ## Alumni Ventures - Type: VC Fund - Location: Manchester, New Hampshire, United States - Relevant deals: 81 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Information Technology Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors. ## Andreessen Horowitz - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 42 - Stages: Series A, Seed, Series B - Focus: Software, Information Technology, Artificial Intelligence Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology. ## SV Aangel - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 38 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Internet SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward. ## Khosla Ventures - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 36 - Stages: Series A, Series B, Seed - Focus: Software, Artificial Intelligence, Health Care Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies. ## Right Side Capital Management - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 35 - Stages: Seed, Pre-Seed, Convertible Note - Focus: Software, SaaS, Health Care Systematic Pre-Seed Startup Capital ## Accel - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 34 - Stages: Series A, Series B, Seed - Focus: Software, SaaS, Information Technology First partner to exceptional teams everywhere ## DCVC - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 33 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Machine Learning We are deep tech venture capital. ## AME Cloud Ventures - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 33 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, Health Care AME Cloud Ventures invests in seed to later-stage tech companies that build infrastructure and value chains around data. ## Bloomberg Beta - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 32 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Information Technology Bloomberg Beta is an early-stage venture capital firm with $450M under management, capitalized solely by Bloomberg. The fund exists to expand Bloomberg’s horizons by investing in companies built by extraordinary founders that make business work better, with a focus on machine intelligence. ## Greycroft - Type: VC Fund - Location: New York, New York, United States - Relevant deals: 32 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, E-Commerce Venture capital and technology investments ## Madrona - Type: VC Fund - Location: Seattle, Washington, United States - Relevant deals: 32 - Stages: Series A, Series B, Seed - Focus: Software, Artificial Intelligence, SaaS A venture capital firm that teams with technology entrepreneurs to nurture ideas from startup to market success. ## New Enterprise Associates - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 30 - Stages: Series A, Series B, Series C - Focus: Software, Health Care, Biotechnology Foundational partners to ambitious founders at every stage of company-building. ## Hyperplane - Type: VC Fund - Location: Boston, Massachusetts, United States - Relevant deals: 30 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Machine Learning Hyperplane Venture Capital is an investment firm focused on exceptional founders building machine intelligence and data companies. They partner with exceptional founders who are leveraging machine intelligence, sensor technology, and cloud computing to solve the world’s hardest problems uncovering the underlying structure for each problem andcreating solutions at the nexus of perception, communication, intelligence, and insight.The company was founded by Vivjan Myrto, John Murphy and Brendan Kohler in 2015; and is headquartered in Boston, Massachusetts. ## First Round Capital - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 30 - Stages: Seed, Series A, Series B - Focus: Software, Information Technology, Artificial Intelligence First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies. ## General Catalyst - Type: VC Fund - Location: Cambridge, Massachusetts, United States - Relevant deals: 29 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, Health Care Investing in powerful, positive change that endures ## Intel Capital - Type: VC Fund - Location: Santa Clara, California, United States - Relevant deals: 29 - Stages: Series B, Series A, Series C - Focus: Software, Information Technology, Enterprise Software Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies. ## Sierra Ventures - Type: VC Fund - Location: San Mateo, California, United States - Relevant deals: 28 - Stages: Series A, Seed, Series B - Focus: Software, Information Technology, Artificial Intelligence Sierra Ventures is an early-stage venture capital firm investing in the future of enterprise, healthcare, infrastructure, and more. ## Lux Capital - Type: VC Fund - Location: New York, New York, United States - Relevant deals: 26 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, Health Care Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors. ## Morado Ventures - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 26 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Enterprise Software A tech-forward seed fund backing exceptional founders building the next generation of transformative companies ## Lightspeed Venture Partners - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 25 - Stages: Series A, Series B, Seed - Focus: Software, Information Technology, Artificial Intelligence Lightspeed Venture Partners is a multi-stage venture capital firm focused on accelerating disruptive innovations and trends. ## Gradient - Type: VC Fund - Location: Mountain View, California, United States - Relevant deals: 25 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Information Technology Gradient is a seed fund that focuses on supporting founders in the artificial intelligence sector. The firm collaborates closely with innovators to integrate AI into various business processes and drive technological advancements. Gradient aims to foster disruptive ideas that can redefine industries and enhance operational capabilities. ## Uncork Capital - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 25 - Stages: Seed, Series A, Series B - Focus: Software, SaaS, Analytics For more than 20 years, Uncork has focused on one stage: seed. Our partners have invested in over 290 companies, with more than 100 meaningful outcomes and $60B+ in enterprise value created — including Fitbit (NYSE: FIT, Google), Sendgrid (NYSE: SEND, Twilio), Eventbrite (NYSE: EB), Poshmark (NASD: POSH), and Postmates (UBER), as well asfast-growing startups like We invest in companies using AI and emerging technologies to create leverage, unlock scale, and push industries forward. We're typically the first major check on the cap table, often leading seed rounds with an initial investment of $3M-$5M. We keep terms simple and transparent, because a clean term sheet makes a strong partnership.We look for team, TAM, and tailwinds, but conviction in founder–market fit comes above all else. We back founders who bring sharp insight into their markets and the drive to build what others can’t yet see.There’s no single playbook for building a company. Every journey looks different, but our role stays the same: a steady partner who shows up early, knows when to deliver hard truths, and stays engaged long after the round closes.Learn more at ## Bain Capital Ventures - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 25 - Stages: Series A, Series B, Seed - Focus: Software, Information Technology, FinTech Bain Capital Ventures helps founders build iconic businesses that transform the way we live and work. ## BootstrapLabs - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 24 - Stages: Seed, Series A, Pre-Seed - Focus: Artificial Intelligence, Machine Learning, Software BootstrapLabs is a leading early-stage Venture Capital firm based in San Francisco focused on Applied AI - that was founded by entrepreneurs for entrepreneurs. The firm understands firsthand the needs and challenges of building a startup, and invests early in potentially disruptive Applied AI technology startups with global potential. And isuncovering the future by investing in Applied AI. Key sectors of interest include Transportation, Logistic, Energy, FinTech, Future of Work (FoW), Security, Internet of Things (IoT), HealthTech, and others. ## Sequoia Capital - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 24 - Stages: Series A, Series B, Series C - Focus: Software, Information Technology, Artificial Intelligence We help the daring build We help the daring build legendary companies from idea to IPO and beyond. companies. ## Homebrew - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 24 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Information Technology Seed venture capital and operational expertise for mission-driven entrepreneurs ## Zetta Venture Partners - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 24 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Machine Learning Venture Capital for AI Native Startups ## Amplify Partners - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 24 - Stages: Series A, Seed, Series B - Focus: Software, Information Technology, Artificial Intelligence Amplify is the first investor for technical founders building the next generation of technical applications, tools, and platforms. ## Two Sigma Ventures - Type: VC Fund - Location: New York, New York, United States - Relevant deals: 24 - Stages: Series A, Series B, Seed - Focus: Software, Artificial Intelligence, Machine Learning We are an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power to change the world. ## Founders Fund - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 23 - Stages: Series A, Seed, Series B - Focus: Software, Health Care, Information Technology Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies. ## 8VC - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 23 - Stages: Series A, Seed, Series B - Focus: Software, Health Care, Artificial Intelligence 8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics. ## Kleiner Perkins - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 23 - Stages: Series B, Series A, Series C - Focus: Software, Information Technology, Health Care Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley. ## Streamlined - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 23 - Stages: Seed, Series A - Focus: Software, Artificial Intelligence, Information Technology We partner with seed-stage founders to build exceptional companies. ## Liquid 2 Ventures - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 22 - Stages: Seed, Series A, Pre-Seed - Focus: Software, Artificial Intelligence, Information Technology Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma. ## Ulu Ventures - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 22 - Stages: Seed, Series A - Focus: Software, Financial Services, FinTech With deep connections to Stanford and Silicon Valley, Ulu Ventures is a venture capital firm that actively seeks and funds women and diverse founder teams. ## Google Ventures - Type: VC Fund - Location: Mountain View, California, United States - Relevant deals: 22 - Stages: Series A, Series B, Seed - Focus: Software, Health Care, Biotechnology GV supports innovative founders moving the world forward. ## M12 - Microsoft's Venture Fund - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 21 - Stages: Series A, Series B, Series C - Focus: Software, Artificial Intelligence, Machine Learning M12 are a venture capital fund, by Microsoft. Our investment teams are based globally to support your business from start up funding to Series C investment. ## SignalFire - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 21 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, Information Technology Engineered to ignite your growth, SignalFire is the first venture capital firm built as a technology company. Data, advice, and support from seed to scale. ## BoxGroup - Type: VC Fund - Location: New York, New York, United States - Relevant deals: 21 - Stages: Seed, Series A, Series B - Focus: Software, Health Care, Artificial Intelligence BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com ## TSVC - Type: VC Fund - Location: Los Altos, California, United States - Relevant deals: 21 - Stages: Seed, Series A - Focus: Software, Artificial Intelligence, Health Care Founded in 2010, TSVC (formerly TEEC Angel Fund) is proud to be a leading early-stage venture capital fund in Silicon Valley. ## Emergent Ventures - Type: VC Fund - Location: San Mateo, California, United States - Relevant deals: 20 - Stages: Seed, Series A, Pre-Seed - Focus: Software, Artificial Intelligence, Information Technology Day 0 backers for ambitious founders. Based in Silicon Valley, Emergent Ventures partners closely, provides deep GTM support and helps build category-defining companies in enterprise AI, Cloud, and beyond. ## Social Starts - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 20 - Stages: Seed, Series A - Focus: Software, Health Care, Artificial Intelligence Social Starts is a $60M+ venture capital partnership with a uniquely data-driven approach to investing in moment-of-inception and Series A financing rounds. ## Felicis - Type: VC Fund - Location: Menlo Park, California, United States - Relevant deals: 20 - Stages: Series A, Seed, Series B - Focus: Software, Artificial Intelligence, SaaS Backing founders building iconic companies that transcend boundaries ## Costanoa Ventures - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 20 - Stages: Seed, Series A, Series B - Focus: Software, Artificial Intelligence, Information Technology Bold Ideas Enduring Companies ## Foundation Capital - Type: VC Fund - Location: Palo Alto, California, United States - Relevant deals: 20 - Stages: Seed, Series A, Series B - Focus: Software, Information Technology, Artificial Intelligence For 30 years we've backed extraordinary founders from day zero. ## Matrix - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 20 - Stages: Series B, Series A, Series C - Focus: Software, Artificial Intelligence, Information Technology We're an early stage VC firm that leads pre-seed through Series A rounds and works with founders to help them win. ## Cultivation Capital - Type: VC Fund - Location: St Louis, Missouri, United States - Relevant deals: 19 - Stages: Seed, Series A - Focus: Software, SaaS, Health Care Cultivation Capital invests in young companies whose ideas have potential to transform the way we live and work. ## RRE Ventures - Type: VC Fund - Location: New York, New York, United States - Relevant deals: 19 - Stages: Series A, Seed, Series B - Focus: Software, Financial Services, Internet RRE is a boutique venture capital firm with 30 years of experience, backing bold early-stage founders across diverse sectors. We provide deep expertise, AI-driven insights, and committed partnerships to help companies build and persevere for the long term. ## 1984 Ventures - Type: VC Fund - Location: San Francisco, California, United States - Relevant deals: 19 - Stages: Seed, Series A, Pre-Seed - Focus: Software, Health Care, Artificial Intelligence 1984 Ventures is an early-stage venture capital firm that seeks to invest in fintech, healthcare, SaaS, e-commerce, and consumer sectors. ## Flying Fish Partners - Type: VC Fund - Location: Seattle, Washington, United States - Relevant deals: 19 - Stages: Seed, Series A - Focus: Software, Artificial Intelligence, Machine Learning Investing in the transformative power of Artificial Intelligence and Machine Learning.